Gleevec, an Abl Family Inhibitor, Produces a Profound Change in Cell Shape and Migration

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Chen, Zaozao ^a   Lessey, Elizabeth ^a   Berginski, Matthew E ^b   Cao, Li ^c   Li, Jonathan ^c   Trepat, Xavier ^d   Itano, Michelle ^a   Gomez, Shawn M ^a,b,f   Kapustina, Maryna ^a   Huang, Cai ^e   Burridge, Keith ^a   Truskey, George ^c   Jacobson, Ken ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c Duke University   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e UNIVERSITY OF KENTUCKY   (United States)

^f Brooks Computer Science Building   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; IMATINIB; INTEGRIN; MYOSIN; PROTEIN TYROSINE KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; BLADDER TUMOR; CELL ADHESION; CELL MIGRATION; CELL SHAPE; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; FLUORESCENCE MICROSCOPY; INTERFERENCE REFLECTION MICROSCOPY; LAMINAR FLOW; NONHUMAN; RAT; TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY; TUMOR CELL;

ACTINS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CELL ADHESION; CELL MOVEMENT; CELL SHAPE; MICROSCOPY, INTERFERENCE; MYOSINS; PHENOTYPE; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; RATS; RHOA GTP-BINDING PROTEIN; SHEAR STRENGTH; STRESS, MECHANICAL; TUMOR CELLS, CULTURED; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

RATTUS;

EID: 84871805640     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052233     Document Type: Article

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