Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44173-44183

  Mishra, Arun K ^a   Alves, Joana E ^b   Krumbach, Karin ^c   Nigou, Jerome ^d,e   Castro, António G ^b   Geurtsen, Jeroen ^f   Eggeling, Lothar ^c   Saraiva, Margarida ^b   Besra, Gurdyal S ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF MINHO   (Portugal)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^e UNIVERSITÉ DE TOULOUSE   (France)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARABINANS; BIOCHEMICAL ANALYSIS; CELL DIFFERENTIATION; CELL RESPONSE; CORYNEBACTERIUM GLUTAMICUM; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOKINES; DENDRITIC CELLS; GLYCOSYL TRANSFERASE; IMMUNE RESPONSE; IN-VITRO; IN-VIVO; INNATE IMMUNE RESPONSE; LIPOARABINOMANNANS; LIPOMANNAN; MYCOBACTERIUM TUBERCULOSIS; PATHOGEN-ASSOCIATED MOLECULAR PATTERNS; PATTERN RECOGNITION RECEPTORS; STRUCTURAL VARIATIONS; TOLL-LIKE RECEPTORS; WILD TYPES;

BIOCHEMISTRY; IMMUNOLOGY; PATTERN RECOGNITION;

LIGANDS;

ALPHA (1-2) ARABINOFURANOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; LIPOARABINOMANNAN; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FEMALE; GENE LOCUS; HELPER CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CORYNEBACTERIUM GLUTAMICUM; CORYNEBACTERIUM INFECTIONS; FEMALE; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; POLYSACCHARIDES; TH17 CELLS;

CORYNEBACTERIUM GLUTAMICUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 84871782017     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.402396     Document Type: Article

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