ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney

Nature Communications

Volumn 3, Issue , 2012, Pages

  Naguro, Isao ^a   Umeda, Tsuyoshi ^a   Kobayashi, Yumie ^a   Maruyama, Junichi ^a   Hattori, Kazuki ^a   Shimizu, Yutaka ^a   Kataoka, Keiichiro ^b   Kim Mitsuyama, Shokei ^b   Uchida, Shinichi ^c   Vandewalle, Alain ^d   Noguchi, Takuya ^a   Nishitoh, Hideki ^a   Matsuzawa, Atsushi ^a   Takeda, Kohsuke ^a   Ichijo, Hidenori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 3; OXIDATIVE STRESS RESPONSIVE KINASE 1; PHOSPHOTRANSFERASE; PROTEIN KINASE WNK1; PROTEIN SERINE THREONINE KINASE; STE20 SPS1 RELATED PROLINE ALANINE RICH KINASE; UNCLASSIFIED DRUG;

BLOOD SYSTEM DISORDER; BODY FLUID; ENZYME ACTIVITY; HOMEOSTASIS; OSMOSIS; PHENOTYPE; SIGNAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; KIDNEY TUBULE; MALE; MOUSE; NONHUMAN; OSMOTIC STRESS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD PRESSURE; HELA CELLS; HUMANS; KIDNEY; KIDNEY TUBULES; MALE; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; OSMOTIC PRESSURE; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

MAMMALIA; MUS;

EID: 84871765729     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2283     Document Type: Article

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