Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64

Integrative Biology (United Kingdom)

Volumn 5, Issue 1, 2013, Pages 231-238

  Bhatnagar, Parijat ^a   Li, Zheng ^b   Choi, Yoonsu ^c   Guo, Jianfeng ^b   Li, Feng ^b   Lee, Daniel Y ^b   Figliola, Matthew ^c   Huls, Helen ^c   Lee, Dean A ^c,d   Zal, Tomasz ^c   Li, King C ^b   Cooper, Laurence J N ^c,d  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; CHIMERIC PROTEIN; COPPER 64; GOLD NANOPARTICLE; MACROGOL; T LYMPHOCYTE RECEPTOR; TETRAXETAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; IN VIVO STUDY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 84871758126     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib20093g     Document Type: Article

References (44)

1. N. P. Restifo M. E. Dudley S. A. Rosenberg Adoptive immunotherapy for cancer: harnessing the T cell response Nat. Rev. Immunol. 2012 12 269 281
2. S. A. Rosenberg Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know Nat. Rev. Clin. Oncol. 2011 8 577 585
3. S. A. Grupp and C. H. June, in Cancer Immunology and Immunotherapy, ed., G. Dranoff, 2011, vol. 344, pp. 149-172
4. C. Bonini M. K. Brenner H. E. Heslop R. A. Morgan Genetic Modification of T Cells Biol. Blood Marrow Transplant. 2011 17 S15 S20
5. B. Jena G. Dotti L. J. N. Cooper Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor Blood 2010 116 1035 1044
6. L. Gattinoni D. J. Powell S. A. Rosenberg N. P. Restifo Adoptive immunotherapy for cancer: building on success Nat. Rev. Immunol. 2006 6 383 393
7. D. B. Kohn G. Dotti R. Brentjens B. Savoldo M. Jensen L. J. N. Cooper C. H. June S. Rosenberg M. Sadelain H. E. Heslop CARs on track in the clinic Mol. Ther. 2011 19 432 438
8. E. D. Nair-Gill C. J. Shu C. G. Radu O. N. Witte Non-invasive imaging of adaptive immunity using positron emission tomography Immunol. Rev. 2008 221 214 228
9. B. A. Rabinovich Y. Ye T. Etto J. Q. Chen H. I. Levitsky W. W. Overwijk L. J. N. Cooper J. Gelovani P. Hwu Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer Proc. Natl. Acad. Sci. U. S. A. 2008 105 14342 14346
10. H. Singh A. M. Najjar S. Olivares R. Nishii U. Mukhopadhyay M. Alauddin P. R. Manuri H. Huls D. A. Lee G. Dotti C. Bollard P. J. Simmons E. J. Shpall R. E. Champlin J. G. Gelovani L. J. N. Cooper PET imaging of T cells derived from umbilical cord blood Leukemia 2009 23 620 622
11. G. Dotti M. Tian B. Savoldo A. Najjar L. J. N. Cooper J. Jackson A. Smith O. Mawlawi R. Uthamanthil A. Borne D. Brammer V. Paolillo M. Alauddin C. Gonzalez D. Steiner W. K. Decker F. Marini S. Kornblau C. M. Bollard E. J. Shpall J. G. Gelovani Repetitive Noninvasive Monitoring of HSV1-tk-Expressing T Cells Intravenously Infused into Nonhuman Primates Using Positron Emission Tomography and Computed Tomography with F-18-FEAU Mol. Imaging 2009 8 230 237
12. S. S. Yaghoubi M. C. Jensen N. Satyamurthy S. Budhiraja D. Paik J. Czernin S. S. Gambhir Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma Nat. Clin. Pract. Oncol. 2009 6 53 58
13. K. Dobrenkov M. Olszewska Y. Likar L. Shenker G. Gunset S. Cai N. Pillarsetty H. Hricak M. Sadelain V. Ponomarev Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging J. Nucl. Med. 2008 49 1162 1170
14. S. A. Collins K. Hiraoka A. Inagaki N. Kasahara M. Tangney PET imaging for gene & cell therapy Curr. Gene Ther. 2012 12 20 32
15. N. Adonai K. N. Nguyen J. Walsh M. Iyer T. Toyokuni M. E. Phelps T. McCarthy D. W. McCarthy S. S. Gambhir Ex vivo cell labeling with Cu-64-pyruvaldehyde-bis(N-4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography Proc. Natl. Acad. Sci. U. S. A. 2002 99 3030 3035
16. E. Oh J. B. Delehanty K. E. Sapsford K. Susumu R. Goswami J. B. Blanco-Canosa P. E. Dawson J. Granek M. Shoff Q. Zhang P. L. Goering A. Huston I. L. Medintz Cellular Uptake and Fate of PEGylated Gold Nanoparticles Is Dependent on Both Cell-Penetration Peptides and Particle Size ACS Nano 2011 5 6434 6448
17. D. B. Chithrani Intracellular uptake, transport, and processing of gold nanostructures Mol. Membr. Biol. 2010 27 299 311
18. P. Nativo I. A. Prior M. Brust Uptake and intracellular fate of surface-modified gold nanoparticles ACS Nano 2008 2 1639 1644
19. M. A. Swartz S. Hirosue J. A. Hubbell Engineering approaches to immunotherapy Sci. Transl. Med. 2012 4 148
20. M. F. Kircher S. S. Gambhir J. Grimm Noninvasive cell-tracking methods Nat. Rev. Clin. Oncol. 2011 8 677 688
21. A. C. Parente-Pereira J. Burnet D. Ellison J. Foster D. M. Davies S. van der Stegen S. Burbridge L. Chiapero-Stanke S. Wilkie S. Mather J. Maher Trafficking of CAR-Engineered Human T Cells Following Regional or Systemic Adoptive Transfer in SCID Beige Mice J. Clin. Immunol. 2011 31 710 718
22. R. C. Koya S. Mok B. Comin-Anduix T. Chodon C. G. Radu M. I. Nishimura O. N. Witte A. Ribas Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses Proc. Natl. Acad. Sci. U. S. A. 2010 107 14286 14291
23. K. Matsui Z. Wang T. J. McCarthy P. M. Allen D. E. Reichert Quantitation and visualization of tumor-specific T cells in the secondary lymphoid organs during and after tumor elimination by PET Nucl. Med. Biol. 2004 31 1021 1031
24. P. B. Hackett D. A. Largaespada L. J. N. Cooper A Transposon and Transposase System for Human Application Mol. Ther. 2010 18 674 683
25. H. Singh M. J. Figliola M. J. Dawson H. Huls S. Olivares K. Switzer T. J. Mi S. Maiti P. Kebriaei D. A. Lee R. E. Champlin L. J. N. Cooper Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies Cancer Res. 2011 71 3516 3527
26. H. Singh P. R. Manuri S. Olivares N. Dara M. J. Dawson H. Huls P. B. Hackett D. B. Kohn E. J. Shpall R. E. Champlin L. J. N. Cooper Redirecting specificity of T-cell populations for CD19 using the sleeping beauty system Cancer Res. 2008 68 2961 2971
27. A. Cid-Arregui V. Juarez H. zur Hausen A synthetic E7 gene of human papillomavirus type 16 that yields enhanced expression of the protein in mammalian cells and is useful for DNA immunization studies J. Virol. 2003 77 4928 4937
28. S. S. Patterson H. M. Dionisi R. K. Gupta G. S. Sayler Codon optimization of bacterial luciferase (lux) for expression in mammalian cells J. Ind. Microbiol. Biotechnol. 2005 32 115 123
29. P. V. R. Manuri M. H. Wilson S. N. Maiti T. J. Mi H. Singh S. Olivares M. J. Dawson H. Huls D. A. Lee P. H. Rao J. M. Kaminski Y. Nakazawa S. Gottschalk P. Kebriaei E. J. Shpall R. E. Champlin L. J. N. Cooper piggyBac Transposon/Transposase System to Generate CD19-Specific T Cells for the Treatment of B-Lineage Malignancies Hum. Gene Ther. 2010 21 427 437
30. T. K. Nayak M. W. Brechbiel Radioimmunoimaging with Longer-Lived Positron-Emitting Radionuclides: Potentials and Challenges Bioconjugate Chem. 2009 20 825 841
31. M. Shokeen C. J. Anderson Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET) Acc. Chem. Res. 2009 42 832 841
32. H. S. Choi W. Liu P. Misra E. Tanaka J. P. Zimmer B. Itty Ipe M. G. Bawendi J. V. Frangioni Renal clearance of quantum dots Nat. Biotechnol. 2007 25 1165 1170
33. B. D. Chithrani A. A. Ghazani W. C. W. Chan Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells Nano Lett. 2006 6 662 668
34. C. Chen S. W. Smye M. P. Robinson J. A. Evans Membrane electroporation theories: a review Med. Biol. Eng. Comput. 2006 44 5 14
35. C. Favard D. S. Dean M. P. Rols Electrotransfer as a non-viral method of gene delivery Curr. Gene Ther. 2007 7 67 77
36. W. D. James L. R. Hirsch J. L. West P. D. O'Neal J. D. Payne Application of INAA to the build-up and clearance of gold nanoshells in clinical studies in mice J. Radioanal. Nucl. Chem. 2007 271 455 459
37. T. Niidome M. Yamagata Y. Okamoto Y. Akiyama H. Takahashi T. Kawano Y. Katayama Y. Niidome PEG-modified gold nanorods with a stealth character for in vivo applications J. Controlled Release 2006 114 343 347
38. L. C. Kennedy A. S. Bear J. K. Young N. A. Lewinski J. Kim A. E. Foster R. A. Drezek T cells enhance gold nanoparticle delivery to tumors in vivo Nanoscale Res. Lett. 2011 6 283
39. M. R. Choi K. J. Stanton-Maxey J. K. Stanley C. S. Levin R. Bardhan D. Akin S. Badve J. Sturgis J. P. Robinson R. Bashir N. J. Halas S. E. Clare A cellular Trojan horse for delivery of therapeutic nanoparticles into tumors Nano Lett. 2007 7 3759 3765
40. K. Harrington L. Alvarez-Vallina M. Crittenden M. Gough H. Chong R. M. Diaz G. Vassaux N. Lemoine R. Vile Cells as vehicles for cancer gene therapy: the missing link between targeted vectors and systemic delivery? Hum. Gene Ther. 2002 13 1263 1280
41. W. J. Lesterhuis J. Haanen C. J. A. Punt Cancer immunotherapy-revisited Nat. Rev. Drug Discovery 2011 10 591 600
42. J. K. Davies H. Singh H. Huls D. Yuk D. A. Lee P. Kebriaei R. E. Champlin L. M. Nadler E. C. Guinan L. J. N. Cooper Combining CD19 Redirection and Alloanergization to Generate Tumor-Specific Human T Cells for Allogeneic Cell Therapy of B-Cell Malignancies Cancer Res. 2010 70 3915 3924
43. G. D. Zhang Z. Yang W. Lu R. Zhang Q. Huang M. Tian L. Li D. Liang C. Li Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice Biomaterials 2009 30 1928 1936
44. Z. B. Li W. B. Cai Q. Z. Cao K. Chen Z. H. Wu L. N. He X. Y. Chen 64Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression J. Nucl. Med. 2007 48 1162 1171