Time-dependent biodistribution and transgene expression of a recombinant human adenovirus serotype 5-luciferase vector as a surrogate for rAd5-FMDV vaccines in cattle

Veterinary Immunology and Immunopathology

Volumn 151, Issue 1-2, 2013, Pages 37-48

  Montiel, N A ^a   Smoliga, G ^a   Arzt, J ^a  

^a PLUM ISLAND ANIMAL DISEASE CENTER   (United States)

Author keywords

Adenovirus; Biodistribution; Cattle; Foot and mouth disease; Luciferase vector

Indexed keywords

FOOT AND MOUTH DISEASE VACCINE; LUCIFERASE; MESSENGER RNA; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN DETECTION; ANTIGEN PRESENTING CELL; ARTICLE; CATTLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; FOOT AND MOUTH DISEASE; GENE EXPRESSION; HUMAN ADENOVIRUS 5; IN VITRO STUDY; INFLAMMATORY INFILTRATE; INOCULATION; MICROSCOPY; MOLECULAR DYNAMICS; NONHUMAN; RNA TRANSCRIPTION; TRANSGENE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; CAPSID PROTEINS; CATTLE; CATTLE DISEASES; CELLS, CULTURED; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GENE EXPRESSION; GENETIC VECTORS; HUMANS; LUCIFERASES; MALE; TIME FACTORS; TISSUE DISTRIBUTION; VACCINES, SYNTHETIC; VIRAL VACCINES;

ADENOVIRIDAE; BOS; BOVINAE; FOOT-AND-MOUTH DISEASE VIRUS; HUMAN ADENOVIRUS; HUMAN ADENOVIRUS TYPE 5;

EID: 84871686437     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.10.003     Document Type: Article

References (36)

1. Alesci S., Perera S.M., Lai E.W., Kukura C., Abu-Asab M., Tsokos M., Morris J.C., Pacak K. Adenoviral gene transfer in bovine adrenomedullary and murine pheochromocytoma cells: potential clinical and therapeutic relevance. Endocrinology 2007, 148:3900-3907.
2. Arzt J., Gregg D.A., Clavijo A., Rodriguez L.L. Optimization of immunohistochemical and fluorescent antibody techniques for localization of foot-and-mouth disease virus in animal tissues. J. Vet. Diagn. Invest. 2009, 21:779-792.
3. Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature 1998, 392:245-252.
4. Bernt K.M., Ni S., Gaggar A., Li Z.Y., Shayakhmetov D.M., Lieber A. The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors. Mol. Ther. 2003, 8:746-755.
5. Doel T.R. FMD vaccines. Virus Res. 2003, 91:81-99.
6. Duncan S.J., Gordon F.C., Gregory D.W., McPhie J.L., Postlethwaite R., White R., Willcox H.N. Infection of mouse liver by human adenovirus type 5. J. Gen. Virol. 1978, 40:45-61.
7. Everett R.S., Gerrard D.E., Grant A.L. Factors affecting production of luciferase and epitope-tagged IGF-I in porcine muscle after DNA injection. J. Endocrinol. 2000, 166:255-263.
8. Fauquet C., Mayo M., Maniloff J., Desselberger U., Ball L. Virus Taxonomy: VIIIth Report of the International Committee on Taxonomy of Viruses 2005, Elsevier/Academic Press, San Diego, CA.
9. Frucht D.M., Fukao T., Bogdan C., Schindler H., O'Shea J.J., Koyasu S. IFN-gamma production by antigen-presenting cells: mechanisms emerge. Trends Immunol. 2001, 22:556-560.
10. Graham F.L., Smiley J., Russell W.C., Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 1977, 36:59-74.
11. Grubman M., Moraes M., Schutta C., Barrera J., Neilan J., Ettyreddy D., Butman B., Brough D., Brake D. Adenovirus serotype 5-vectored foot-and-mouth disease subunit vaccines: the first decade. Future Virol. 2010, 5:51-64.
12. Grubman M.J., Baxt B. Foot-and-mouth disease. Clin. Microbiol. Rev. 2004, 17:465-493.
13. Guidotti L.G., Chisari F.V. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 2001, 19:65-91.
14. Jackson S.S., Schmitz J.E., Letvin N.L. Anti-gamma interferon antibodies enhance the immunogenicity of recombinant adenovirus vectors. Clin. Vaccine Immunol. 2011, 18.
15. Manthorpe M., Cornefert-Jensen F., Hartikka J., Felgner J., Rundell A., Margalith M., Dwarki V. Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum. Gene Ther. 1993, 4:419-431.
16. Mayr G.A., Chinsangaram J., Grubman M.J. Development of replication-defective adenovirus serotype 5 containing the capsid and 3C protease coding regions of foot-and-mouth disease virus as a vaccine candidate. Virology 1999, 263:496-506.
17. Montiel N., Smoliga G., Arzt J. Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues. Vaccine 2012.
18. Moraes M.P., Mayr G.A., Mason P.W., Grubman M.J. Early protection against homologous challenge after a single dose of replication-defective human adenovirus type 5 expressing capsid proteins of foot-and-mouth disease virus (FMDV) strain A24. Vaccine 2002, 20:1631-1639.
19. Moraes M.P., Segundo F.D., Dias C.C., Pena L., Grubman M.J. Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response. Vaccine 2011, 29:9431-9440.
20. Pacheco J.M., Brum M.C., Moraes M.P., Golde W.T., Grubman M.J. Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit vaccine. Virology 2005, 337:205-209.
21. Pacheco J.M., Piccone M.E., Rieder E., Pauszek S.J., Borca M.V., Rodriguez L.L. Domain disruptions of individual 3B proteins of foot-and-mouth disease virus do not alter growth in cell culture or virulence in cattle. Virology 2010, 405:149-156.
22. Rodriguez L.L., Gay C.G. Development of vaccines toward the global control and eradication of foot-and-mouth disease. Expert Rev. Vaccines 2011, 10:377-387.
23. Rodriguez L.L., Grubman M.J. Foot and mouth disease virus vaccines. Vaccine 2009, 27(Suppl. 4):D90-D94.
24. Sanz-Parra A., Jimenez-Clavero M.A., Garcia-Briones M.M., Blanco E., Sobrino F., Ley V. Recombinant viruses expressing the foot-and-mouth disease virus capsid precursor polypeptide (P1) induce cellular but not humoral antiviral immunity and partial protection in pigs. Virology 1999, 259:129-134.
25. Sanz-Parra A., Vazquez B., Sobrino F., Cox S.J., Ley V., Salt J.S. Evidence of partial protection against foot-and-mouth disease in cattle immunized with a recombinant adenovirus vector expressing the precursor polypeptide (P1) of foot-and-mouth disease virus capsid proteins. J. Gen. Virol. 1999, 80(Pt 3):671-679.
26. Schiaffino S., Partridge T. Skeletal muscle repair and regeneration. Adv. Muscle Res. 2008, 3:380.
27. Senoo M., Matsubara Y., Fujii K., Nagasaki Y., Hiratsuka M., Kure S., Uehara S., Okamura K., Yajima A., Narisawa K. Adenovirus-mediated in utero gene transfer in mice and guinea pigs: tissue distribution of recombinant adenovirus determined by quantitative TaqMan-polymerase chain reaction assay. Mol. Genet. Metab. 2000, 69:269-276.
28. Shayakhmetov D.M., Li Z.Y., Ni S., Lieber A. Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectors. J. Virol. 2004, 78:5368-5381.
29. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985, 150:76-85.
30. Steinman R.M., Inaba K., Turley S., Pierre P., Mellman I. Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Hum. Immunol. 1999, 60:562-567.
31. Sung R.S., Qin L., Bromberg J.S. TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression. Mol. Ther. 2001, 3:757-767.
32. Swaney L.M. A continuous bovine kidney cell line for routine assays of foot-and-mouth disease virus. Vet. Microbiol. 1988, 18:1-14.
33. Torres J.M., Alonso C., Ortega A., Mittal S., Graham F., Enjuanes L. Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus. J. Virol. 1996, 70:3770-3780.
34. Wang Y., Groot-Wassink T., Lemoine N.R., Vassaux G. Cellular characterization of the tropism of recombinant adenovirus for the adrenal glands. Eur. J. Clin. Invest. 2003, 33:794-798.
35. Wolff J.A., Malone R.W., Williams P., Chong W., Acsadi G., Jani A., Felgner P.L. Direct gene transfer into mouse muscle in vivo. Science 1990, 247:1465-1468.
36. Ying B., Toth K., Spencer J.F., Meyer J., Tollefson A.E., Patra D., Dhar D., Shashkova E.V., Kuppuswamy M., Doronin K., Thomas M.A., Zumstein L.A., Wold W.S., Lichtenstein D.L. INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies. Cancer Gene Ther. 2009, 16:625-637.