메뉴 건너뛰기




Volumn 13, Issue 3, 2012, Pages 1043-1048

Silencing of the COPS3 gene by siRNA reduces proliferation of lung cancer cells most likely via induction of cell cycle arrest and apoptosis

Author keywords

Apoptosis; Cell cycle arrest; Cell proliferation; COPS3; Lung cancer

Indexed keywords

COPS3 PROTEIN, HUMAN; ONCOPROTEIN; SMALL INTERFERING RNA;

EID: 84871679186     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.3.1043     Document Type: Article
Times cited : (11)

References (17)
  • 1
    • 0035794541 scopus 로고    scopus 로고
    • COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
    • Bech-Otschir D, Kraft R, Huang X, et al (2001). COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J, 20, 1630-9.
    • (2001) EMBO J , vol.20 , pp. 1630-1639
    • Bech-Otschir, D.1    Kraft, R.2    Huang, X.3
  • 2
    • 0036892178 scopus 로고    scopus 로고
    • The role of new agents in the treatment of non-small cell lung cancer
    • Broker LE, Giaccone G (2002). The role of new agents in the treatment of non-small cell lung cancer. Eur J Cancer, 38, 2347-61.
    • (2002) Eur J Cancer , vol.38 , pp. 2347-2361
    • Broker, L.E.1    Giaccone, G.2
  • 3
    • 79651469214 scopus 로고    scopus 로고
    • Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC
    • Chen L, Liang Z, Tian Q, et al (2011). Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC. J Exp Clin Cancer Res, 30, 18.
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 18
    • Chen, L.1    Liang, Z.2    Tian, Q.3
  • 4
    • 33747226732 scopus 로고    scopus 로고
    • siRNA-based approaches in cancer therapy
    • Devi G R (2006). siRNA-based approaches in cancer therapy. Cancer Gene Ther, 13, 819-29.
    • (2006) Cancer Gene Ther , vol.13 , pp. 819-829
    • Devi, G.R.1
  • 5
    • 0036232986 scopus 로고    scopus 로고
    • Etiology of osteosarcoma
    • Fuchs B, Pritchard DJ (2002). Etiology of osteosarcoma. Clin Orthop, 397, 40-52.
    • (2002) Clin Orthop , vol.397 , pp. 40-52
    • Fuchs, B.1    Pritchard, D.J.2
  • 6
    • 0035886552 scopus 로고    scopus 로고
    • Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma
    • Gokgoz N, Wunder JS, Mousses S, et al (2001). Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma. Cancer, 92, 2181-9.
    • (2001) Cancer , vol.92 , pp. 2181-2189
    • Gokgoz, N.1    Wunder, J.S.2    Mousses, S.3
  • 7
    • 0042355199 scopus 로고    scopus 로고
    • Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
    • Henriksen J, Aagesen TH, Maelandsmo GM, et al (2003). Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation. Oncogene, 22, 5358-61.
    • (2003) Oncogene , vol.22 , pp. 5358-5361
    • Henriksen, J.1    Aagesen, T.H.2    Maelandsmo, G.M.3
  • 8
    • 66149091940 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
    • Luo J, Emanuele MJ, Li D, et al (2009). A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell, 137, 835-48.
    • (2009) Cell , vol.137 , pp. 835-848
    • Luo, J.1    Emanuele, M.J.2    Li, D.3
  • 9
    • 0141502041 scopus 로고    scopus 로고
    • siRNAs and shRNAs: skeleton keys to the human genome
    • Paddison PJ, Hannon GJ (2003). siRNAs and shRNAs: skeleton keys to the human genome. Curr Opin Mol Ther, 5, 217-24.
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 217-224
    • Paddison, P.J.1    Hannon, G.J.2
  • 11
    • 54249087596 scopus 로고    scopus 로고
    • RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
    • Singh A, Boldin-Adamsky S, Thimmulappa RK, et al (2008). RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res, 68, 7975-84.
    • (2008) Cancer Res , vol.68 , pp. 7975-7984
    • Singh, A.1    Boldin-Adamsky, S.2    Thimmulappa, R.K.3
  • 12
    • 82755187248 scopus 로고    scopus 로고
    • MicroRNA in lung cancer diagnostics and treatment
    • Skrzypski M, Dziadziuszko R, Jassem J (2011). MicroRNA in lung cancer diagnostics and treatment. Mutat Res, 17, 25-31.
    • (2011) Mutat Res , vol.17 , pp. 25-31
    • Skrzypski, M.1    Dziadziuszko, R.2    Jassem, J.3
  • 13
    • 2942534115 scopus 로고    scopus 로고
    • Overexpression through amplification of genes in chromosome region 17p11.2 approximately p12 in high-grade osteosarcoma
    • van Dartel M, Redeker S, Bras J, Kool M, Hulsebos TJ (2004). Overexpression through amplification of genes in chromosome region 17p11.2 approximately p12 in high-grade osteosarcoma. Cancer Genet Cytogenet, 152, 8-14.
    • (2004) Cancer Genet Cytogenet , vol.152 , pp. 8-14
    • van Dartel, M.1    Redeker, S.2    Bras, J.3    Kool, M.4    Hulsebos, T.J.5
  • 15
    • 0141669190 scopus 로고    scopus 로고
    • COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast
    • Yan J, Walz K, Nakamura H, et al (2003). COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol Cell Biol, 23, 6798-808.
    • (2003) Mol Cell Biol , vol.23 , pp. 6798-6808
    • Yan, J.1    Walz, K.2    Nakamura, H.3
  • 16
    • 34247603882 scopus 로고    scopus 로고
    • COPS3 amplification and clinical outcome in osteosarcoma
    • Yan T, Wunder JS, Gokgoz N, et al (2007). COPS3 amplification and clinical outcome in osteosarcoma. Cancer, 109, 1870-6.
    • (2007) Cancer , vol.109 , pp. 1870-1876
    • Yan, T.1    Wunder, J.S.2    Gokgoz, N.3
  • 17
    • 79956098940 scopus 로고    scopus 로고
    • RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells
    • Yan T, Tang G, Ren T, et al (2011). RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells. Cancer Gene Ther, 18, 450-6.
    • (2011) Cancer Gene Ther , vol.18 , pp. 450-456
    • Yan, T.1    Tang, G.2    Ren, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.