The pharmacological NF-κB inhibitor BAY11-7082 induces cell apoptosis and inhibits the migration of human uveal melanoma cells

International Journal of Molecular Sciences

Volumn 13, Issue 12, 2012, Pages 15653-15667

  Hu, Shuiqing ^a   Luo, Qingqiong ^a   Cun, Biyun ^a   Hu, Dan ^a   Ge, Shengfang ^a   Fan, Xianqun ^a   Chen, Fuxiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; BAY11 7082; Cell migration; NF B; Uveal melanoma

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; BAX PROTEIN, MOUSE; BCL2 PROTEIN, MOUSE; NITRILE; SULFONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL MIGRATION; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOMA CELL; MIGRATION INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UVEA MELANOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; MELANOMA; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; UVEAL NEOPLASMS;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MELANOMA; MICE; MICE, INBRED BALB C; MICE, NUDE; NF-KAPPA B; NITRILES; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONES; UVEAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84871676255     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131215653     Document Type: Article

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