Protective Effect of Tropisetron on Rodent Hepatic Injury after Trauma-Hemorrhagic Shock through P38 MAPK-Dependent Hemeoxygenase-1 Expression

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Liu, Fu Chao ^a,b   Yu, Huang Ping ^a,b   Hwang, Tsong Long ^c   Tsai, Yung Fong ^a,b,c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHROMIUM MESOPORPHYRIN; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 3; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESOPORPHYRIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; TROPISETRON; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME ACTIVITY; FLUID RESUSCITATION; HEMORRHAGIC SHOCK; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; TREATMENT OUTCOME;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOPROTECTION; HEME OXYGENASE-1; INDOLES; LIVER; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; WOUNDS AND INJURIES;

ANIMALIA; RATTUS; RODENTIA;

EID: 84871675373     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053203     Document Type: Article

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