Role of inhibition of p38 mitogen-activated protein kinase in liver dysfunction after hemorrhagic shock and resuscitation

Journal of Surgical Research

Volumn 178, Issue 2, 2012, Pages 827-832

  Lv, Kai Yang ^a   Yu, Xi Ya ^a   Bai, Yu Shu ^a   Zhu, Shi Hui ^a   Tang, Hong Tai ^a   Ben, Dao Feng ^a   Xiao, Shi Chu ^a   Wang, Guang Yi ^a   Ma, Bing ^a   Xia, Zhao Fan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Liver dysfunction; p38 mitogen activated protein kinase; Resuscitation; Shock

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; HEMORRHAGIC SHOCK; LIVER CELL DAMAGE; LIVER DYSFUNCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESUSCITATION;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; IMIDAZOLES; INTERLEUKIN-1BETA; LIVER; MALE; MICE; MICE, INBRED C57BL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIMIDINES; RESUSCITATION; SHOCK, HEMORRHAGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84869090202     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.04.006     Document Type: Article

References (24)

1. E.M. Bulger, C.M. Tower, and K.J. Warner Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients Shock 36 2011 435
2. R.J. Haywood-Watson, J.B. Holcomb, and E.A. Gonzalez Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation PLoS One 6 2011 e23530
3. H. Sato, T. Tanaka, and K. Kasai Role of p38 mitogen-activated protein kinase on renal dysfunction after hemorrhagic shock in rats Shock 24 2005 488
4. H. Sato, T. Tanaka, and K. Kasai Role of p38 mitogen-activated protein kinase on cardiac dysfunction after hemorrhagic shock in rats Shock 28 2007 291
5. D. Jarrar, P. Wang, and W.G. Cioffi Critical role of oxygen radicals in the initiation of hepatic depression after trauma hemorrhage J Trauma 49 2000 879
6. J. Fan, Y. Li, and R.M. Levy Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: Role of HMGB1-TLR4 signaling J Immunol 178 2007 6573
7. Y. Carter, G. Liu, and A. Fier Effects of tolerizing sublethal hemorrhage on p44/42 and SAPK/JNK Map-kinase activation Shock 18 2002 132
8. D. Jarrar, P. Wang, and G.Y. Song Inhibition of tyrosine kinase signaling after trauma-hemorrhage: A novel approach for improving organ function and decreasing susceptibility to subsequent sepsis Ann Surg 231 2000 399
9. F.C. Barone, E.A. Irving, and A.M. Ray SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia J Pharmacol Exp Ther 296 2001 312
10. M. Asaduzzaman, Y. Wang, and H. Thorlacius Critical role of p38 mitogen-activated protein kinase signaling in septic lung injury Crit Care Med 36 2008 482
11. D. Klintman, X. Li, and S. Santen p38 mitogen-activated protein kinase-dependent chemokine production, leukocyte recruitment, and hepatocellular apoptosis in endotoxemic liver injury Ann Surg 242 2005 830
12. J.M. Prince, R.M. Levy, and R. Yang Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock J Am Coll Surg 202 2006 407
13. Y.T. Jia, W. Wei, and B. Ma Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury J Immunol 179 2007 7808
14. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402
15. H.R. van den Berg, N.A. Khan, and M. van der Zee Synthetic oligopeptides related to the [beta]-subunit of human chorionic gonadotropin attenuate inflammation and liver damage after (trauma) hemorrhagic shock and resuscitation Shock 31 2009 285
16. Y.C. Hsieh, M. Frink, and B.M. Thobe 17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage Mol Immunol 44 2007 2165
17. B.M. Thobe, M. Frink, and F. Hildebrand The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage J Cell Physiol 210 2007 667
18. D. Yoshinari, I. Takeyoshi, and M. Kobayashi Effects of a p38 mitogen-activated protein kinase inhibitor as an additive to university of wisconsin solution on reperfusion injury in liver transplantation Transplantation 72 2001 22
19. M. Kobayashi, I. Takeyoshi, and D. Yoshinari P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver Surgery 131 2002 344
20. A. Cuadrado, and A.R. Nebreda Mechanisms and functions of p38 MAPK signalling Biochem J 429 2010 403
21. L. Devey, D. Ferenbach, and E. Mohr Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism Mol Ther 17 2009 65
22. Y. Yokoyama, W.C. Kitchens, and B. Toth Role of IL-10 in regulating proinflammatory cytokine release by Kupffer cells following trauma-hemorrhage Am J Physiol Gastrointest Liver Physiol 286 2004 G942
23. F. Hildebrand, W.J. Hubbard, and M.A. Choudhry Kupffer cells and their mediators: The culprits in producing distant organ damage after trauma-hemorrhage Am J Pathol 169 2006 784
24. G. Schindler, M. Kincius, and R. Liang Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury Microcirculation 16 2009 593