Risk factors for mixed complicated skin and skin structure infections to help tailor appropriate empiric therapy

Surgical Infections

Volumn 13, Issue 6, 2012, Pages 377-382

  Zilberberg, Marya ^a,b   Micek, Scott T ^c   Kollef, Marin H ^c   Shelbaya, Ahmed ^d   Shorr, Andrew F ^e  

^a EviMed Research Group LLC   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c BARNES JEWISH HOSPITAL   (United States)

^d PFIZER INC   (United States)

^e WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSCESS; ACCURACY; ADULT; ALGORITHM; ANTIBIOTIC THERAPY; ARTICLE; DISEASE CLASSIFICATION; FEMALE; HEALTHCARE ASSOCIATED INFECTION; HIGH RISK PATIENT; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; NURSING HOME; PATIENT IDENTIFICATION; PRACTICE GUIDELINE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SKIN INFECTION;

ADULT; AGED; ALGORITHMS; ANTI-BACTERIAL AGENTS; COINFECTION; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HOSPITALIZATION; HUMANS; LENGTH OF STAY; LOGISTIC MODELS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SKIN DISEASES, BACTERIAL; TREATMENT OUTCOME;

EID: 84871626579     PISSN: 10962964     EISSN: 15578674     Source Type: Journal    
DOI: 10.1089/sur.2011.101     Document Type: Article

References (28)

1. Klein E, Smith DL, Laxminarayan R. Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005. Emerg Infect Dis 2007;13:1840-1846. (Pubitemid 350248484)
2. Lipsky BA, Weigelt JA, Gupta V, et al. Skin, soft tissue, bone, and joint infections in hospitalized patients: Epidemiology and microbiological, clinical, and economic outcomes. Infect Control Hosp Epidemiol 2007;28:1290-1298. (Pubitemid 47596568)
3. National Nosocomial Infections Surveillance (NNIS) System Report. Am J Infect Control 2004;32:470.
4. Obritsch MD, Fish DN, MacLaren R, Jung R. National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob Agents Chemother 2004;48:4606-4610. (Pubitemid 39577660)
5. Zilberberg MD, Shorr AF, Micek ST, et al. Epidemiology and outcomes of hospitalizations with complicated skin and skin structure infections: Implications of healthcare-associated infection risk factors. Infect Control Hosp Epidemiol 2009;30:1203-1210.
6. Zilberberg MD, Shorr AF, Micek ST, et al. Hospitalizations with healthcare-associated complicated skin and skin structure infections: Impact of inappropriate empiric therapy on outcomes. J Hosp Med 2010;5:535-540.
7. Micek ST, Hoban AP, Pham V, et al. Bacteremia increases the risk of death among patients with soft tissue infections. Surg Infect 2010;11:169-176.
8. Edelsberg J, Berger A, Weber DJ, et al. Clinical and economic consequences of failure of initial antibiotic therapy for hospitalized patients with complicated skin and skinstructure infections. Infect Control Hosp Epidemiol 2008;29: 160-169. (Pubitemid 351269212)
9. Micek ST, Kollef KE, Reichley RM, et al. Health careassociated pneumonia and community-acquired pneumonia: A single-center experience. Antimicrob Agents Chemother 2007;51:3568-3573. (Pubitemid 47519345)
10. Kollef MH, Shorr A, Tabak YP, et al. Epidemiology and outcomes of health-care-associated pneumonia: Results from a large US database of culture-positive pneumonia. Chest 2005;128:3854-3862. (Pubitemid 43062645)
11. Carratala J, Mykietiuk A, Fernandez-Sabe N, et al. Health care-associated pneumonia requiring hospital admission: Epidemiology, antibiotic therapy and clinical outcomes. Arch Intern Med 2007;167:1393-1399. (Pubitemid 47052438)
12. Shindo Y, Sato S, Muruyama E, et al. Health-care-associated pneumonia among hospitalized patients in a Japanese community hospital. Chest 2009;135:633-640.
13. Alvarez-Lerma F, ICU-Acquired Pneumonia Study Group. Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit. Intensive Care Med 1996;22:387-394. (Pubitemid 26174308)
14. Iregui M, Ward S, Sherman G, et al. Clinical importance of delays in the initiation of appropriate antibiotic treatment for ventilator-associated pneumonia. Chest 2002;122:262-268. (Pubitemid 34754172)
15. Morin CA, Hadler JL. Population-based incidence and characteristics of community-onset Staphylococcus aureus infections with bacteremia in 4 metropolitan Connecticut areas, 1998. J Infect Dis 2001;184:1029-1034. (Pubitemid 32955120)
16. Friedman ND, Kaye KS, Stout JE, et al. Health careassociated bloodstream infections in adults: A reason to change the accepted definition of community-acquired infections. Ann Intern Med 2002;137:791-797. (Pubitemid 35334450)
17. Siegman-Igra Y, Fourer B, Orni-Wasserlauf R, et al. Reappraisal of community-acquired bacteremia: A proposal of a new classification for the spectrum of acquisition of bacteremia. Clin Infect Dis 2002;34:1431-4319.
18. McDonald JR, Friedman ND, Stout JE, et al. Risk factors for ineffective therapy in patients with bloodstream infections. Arch Intern Med 2005;165:308-313. (Pubitemid 40216285)
19. Naimi TS, LeDell KH, Como-Sabetti K, et al. Comparison of community-and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA 2003;290:2976-2984. (Pubitemid 37505530)
20. Tambyah PA, Habib AG, Ng TM, et al. Communityacquired methicillin-resistant Staphylococcus aureus infection in Singapore is usually ''healthcare associated.'' Infect Control Hosp Epidemiol 2003;24:436-438. (Pubitemid 36818513)
21. Shorr AF, Tabak YP, Killian AD, et al. Healthcare-associated bloodstream infection: A distinct entity? Insights from a large US database. Crit Care Med 2006;34:2588-2595. (Pubitemid 44413057)
22. Ibrahim EH, Sherman G, Ward S, et al. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000;118: 146-155. (Pubitemid 30485502)
23. Schramm GE, Johnson JA, Doherty JA, et al. Methicillinresistant Staphylococcus aureus sterile-site infection: The importance of appropriate initial antimicrobial treatment. Crit Care Med 2006;34:2069-2074. (Pubitemid 44305607)
24. Zilberberg MD, Shorr AF, Micek MT, et al. Antimicrobial therapy escalation and hospital mortality among patients with HCAP: A single center experience. Chest 2008:134:963-968.
25. Hospital-Acquired Pneumonia Guideline Committee of the American Thoracic Society and Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired pneumonia, ventilator-associated pneumonia, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
26. Kett DH, Cano E, Quartin AA, et al. Implementation of guidelines for management of possible multidrugresistant pneumonia in intensive care: An observational, multicentre cohort study. Lancet Infect Dis 2011;11: 181-189.
27. Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and softtissue infections. Clin Infect Dis 2005;41:1373-1406. (Pubitemid 41581713)
28. Jenkins TC, Sabel AL, Sarcone EE, et al. Skin and soft tissue infections requiring hospitalization at an academic medical center: Opportunities for antimicrobial stewardship. Clin Infect Dis 2010;51:895-903.