Stereoselective interaction between tetrahydropalmatine enantiomers and CYP enzymes in human liver microsomes

Chirality

Volumn 25, Issue 1, 2013, Pages 43-47

  Sun, Si Yuan ^a   Wang, Yu Qing ^a   Li, Li Ping ^a   Wang, Lu ^a   Zeng, Su ^a   Zhou, Hui ^a   Jiang, Hui Di ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

cytochrome P450; human liver microsomes; stereoselective; tetrahydropalmatine

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; FLUVOXAMINE; KETOCONAZOLE; RECOMBINANT ENZYME; TETRAHYDROPALMATINE;

ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER MICROSOME; METABOLIC RATE; PRIORITY JOURNAL; STEREOCHEMISTRY;

BERBERINE ALKALOIDS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; HUMANS; ISOENZYMES; MICROSOMES, LIVER; STEREOISOMERISM;

EID: 84871614215     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.22110     Document Type: Article

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