Metabotropic glutamate receptor 5 activation enhances tyrosine phosphorylation of the N-methyl-D-aspartate (NMDA) receptor and NMDA-induced cell death in hippocampal cultured neurons

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 12, 2012, Pages 2224-2229

  Takagi, Norio ^a   Besshoh, Shintaro ^a   Marunouchi, Tetsuro ^a   Takeo, Satoshi ^a   Tanonaka, Kouichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Cell injury; Metabotropic glutamate receptor; N methyl D aspartate receptor

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN TYROSINE KINASE; TYROSINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVE SITE; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DEATH; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HIPPOCAMPUS; N-METHYLASPARTATE; NEURONS; PHOSPHORYLATION; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SRC-FAMILY KINASES; TYROSINE; UP-REGULATION;

EID: 84871600678     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00691     Document Type: Article

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