Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing plasmodium parasites based on enzyme activity measurement

ACS Nano

Volumn 6, Issue 12, 2012, Pages 10676-10683

  Juul, Sissel ^a   Nielsen, Christine J F ^b   Labouriau, Rodrigo ^b   Roy, Amit ^b   Tesauro, Cinzia ^c   Jensen, Pia W ^b   Harmsen, Charlotte ^b   Kristoffersen, Emil L ^b   Chiu, Ya Ling ^a   Frohlich, Rikke ^b   Fiorani, Paola ^d   Cox Singh, Janet ^e,h   Tordrup, David ^b   Koch, Jorn ^f   Bienvenu, Anne Lise ^g   Desideri, Alessandro ^c   Picot, Stephane ^g   Petersen, Eskild ^f   Leong, Kam W ^a   Ho, Yi Ping ^b   Stougaard, Magnus ^b,f   Knudsen, Birgitta R ^b   more..

^a Duke University   (United States)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d INSTITUTE OF TRANSLATIONAL PHARMACOLOGY   (Italy)

^e UNIVERSITY OF ST ANDREWS   (United Kingdom)

^f AARHUS UNIVERSITY HOSPITAL   (Denmark)

^g HOSPICES CIVILS DE LYON   (France)

^h UNIVERSITI MALAYSIA SARAWAK   (Malaysia)

Author keywords

diagnosis; droplet microfluidics; enzyme activity detection; lab on a chip; malaria; rolling circle amplification

Indexed keywords

ACTIVITY DETECTION; ACTIVITY MEASUREMENTS; BASIC SCIENCE; DETECTION LIMITS; DROPLET MICROFLUIDICS; FRESH WATER; GENERIC PLATFORMS; HIGH POTENTIAL; INFECTED PATIENTS; LAB-ON-A-CHIP; MALARIA; MALARIA TRANSMISSION; PARASITE; PLASMODIUM PARASITES; POINT OF CARE; QUANTITATIVE DETECTION; SENSITIVE DETECTION; SINGLE DROPS; SINGLE MOLECULE LEVEL; TOPOISOMERASE I;

DIAGNOSIS; DROPS; MICROFLUIDICS;

DISEASES;

ARTICLE; ENZYME ASSAY; ENZYMOLOGY; EQUIPMENT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; METHODOLOGY; MICROFLUIDIC ANALYSIS; NUCLEOTIDE SEQUENCE; PARASITOLOGY; PLASMODIUM FALCIPARUM; SPECIES DIFFERENCE;

BASE SEQUENCE; ENZYME ASSAYS; HUMANS; MALARIA, FALCIPARUM; MICROFLUIDIC ANALYTICAL TECHNIQUES; PLASMODIUM FALCIPARUM; SPECIES SPECIFICITY;

EID: 84871597688     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn3038594     Document Type: Article

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