Ultrasensitive detection of low-abundance surface-marker protein using isothermal rolling circle amplification in a microfluidic nanoliter platform

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Volumn 7, Issue 3, 2011, Pages 395-400

  Konry, Tania ^a   Smolina, Irina ^b   Yarmush, Joel M ^c   Irimia, Daniel ^a   Yarmush, Martin L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Boston University   (United States)

^c NEW YORK METHODIST HOSPITAL   (United States)

Author keywords

antibodies; antigens; biomedical applications; microfluidics; RCA; single molecule detection; tumor markers

Indexed keywords

ANTIBODY RECOGNITION; BIOMEDICAL APPLICATIONS; CANCER BIOLOGY; CELL MARKERS; CELL SURFACES; DNA DETECTION; EARLY DIAGNOSIS; EXISTING METHOD; HIGHLY SENSITIVE; ISOTHERMAL ROLLING; LABELING METHODS; MARKER PROTEINS; MICROFLUIDIC TECHNOLOGIES; NANOLITERS; PROTEIN MARKERS; RCA; REAGENT CONSUMPTION; SENSITIVE SYSTEMS; SIGNAL AMPLIFICATIONS; SINGLE-MOLECULE DETECTION; THERAPEUTIC TOOLS; TUMOR MARKERS; ULTRASENSITIVE DETECTION;

ANTIBODIES; ANTIGENS; CELL MEMBRANES; CHEMICAL DETECTION; DISEASES; DROP FORMATION; MOLECULES; NUCLEIC ACIDS; SIGNAL PROCESSING; SURFACE REACTIONS; TUMORS;

MICROFLUIDICS;

MEMBRANE PROTEIN; TUMOR MARKER;

ANIMAL; ARTICLE; HUMAN; METHODOLOGY; MICROFLUIDICS; NANOTECHNOLOGY;

ANIMALS; HUMANS; MEMBRANE PROTEINS; MICROFLUIDICS; NANOTECHNOLOGY; TUMOR MARKERS, BIOLOGICAL;

EID: 79751513905     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201001620     Document Type: Article

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