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Volumn 13, Issue 1, 2013, Pages 1-4

Integrated clinical genomics: New horizon for diagnostic and biomarker discoveries in cancer

Author keywords

breast cancer; colorectal cancer; copy number changes; genome sequencing; heterogeneity; integrated analysis; mutations; transcriptomics

Indexed keywords

TRANSCRIPTOME; TUMOR MARKER;

EID: 84871555703     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.12.132     Document Type: Review
Times cited : (4)

References (20)
  • 1
    • 79952395270 scopus 로고    scopus 로고
    • Cancer genomics: From discovery science to personalized medicine
    • Chin L, Andersen JN, Futreal PA. Cancer genomics: from discovery science to personalized medicine. Nat. Med. 17(3), 297-303 (2011).
    • (2011) Nat. Med , vol.17 , Issue.3 , pp. 297-303
    • Chin, L.1    Andersen, J.N.2    Futreal, P.A.3
  • 2
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Oslo Breast Cancer Consortium (OSBREAC)
    • Stephens PJ, Tarpey PS, Davies H et al.; Oslo Breast Cancer Consortium (OSBREAC). The landscape of cancer genes and mutational processes in breast cancer. Nature 486(7403), 400-404 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3
  • 3
    • 84862584058 scopus 로고    scopus 로고
    • Wholegenome analysis informs breast cancer response to aromatase inhibition
    • Ellis MJ, Ding L, Shen D et al. Wholegenome analysis informs breast cancer response to aromatase inhibition. Nature 486(7403), 353-360 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 353-360
    • Ellis, M.J.1    Ding, L.2    Shen, D.3
  • 4
    • 84862523863 scopus 로고    scopus 로고
    • Sequence analysis of mutations and translocations across breast cancer subtypes
    • Banerji S, Cibulskis K, Rangel-Escareno C et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 486(7403), 405-409 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 405-409
    • Banerji, S.1    Cibulskis, K.2    Rangel-Escareno, C.3
  • 5
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • Shah SP, Roth A, Goya R et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 486(7403), 395-399 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 395-399
    • Shah, S.P.1    Roth, A.2    Goya, R.3
  • 6
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    • METABRIC Group
    • Curtis C, Shah SP, Chin SF et al.; METABRIC Group. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486(7403), 346-352 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 346-352
    • Curtis, C.1    Shah, S.P.2    Chin, S.F.3
  • 7
    • 84856008906 scopus 로고    scopus 로고
    • Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
    • Ross-Innes CS, Stark R, Teschendorff AE et al. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature 481(7381), 389-393 (2012).
    • (2012) Nature , vol.481 , Issue.7381 , pp. 389-393
    • Ross-Innes, C.S.1    Stark, R.2    Teschendorff, A.E.3
  • 8
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 487(7407), 330-337 (2012).
    • (2012) Nature , vol.487 , Issue.7407 , pp. 330-337
  • 9
    • 84865459654 scopus 로고    scopus 로고
    • Recurrent R-spondin fusions in colon cancer
    • Seshagiri S, Stawiski EW, Durinck S et al. Recurrent R-spondin fusions in colon cancer. Nature 488(7413), 660-664 (2012).
    • (2012) Nature , vol.488 , Issue.7413 , pp. 660-664
    • Seshagiri, S.1    Stawiski, E.W.2    Durinck, S.3
  • 10
    • 77955596399 scopus 로고    scopus 로고
    • Next-generation, genome sequencing-based biomarkers: Concerns and challenges for medical practice
    • Roukos DH. Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice. Biomark. Med. 4(4), 583-586 (2010).
    • (2010) Biomark. Med , vol.4 , Issue.4 , pp. 583-586
    • Roukos, D.H.1
  • 11
    • 78149381840 scopus 로고    scopus 로고
    • Next-generation sequencing and epigenome technologies: Potential medical applications
    • Roukos DH. Next-generation sequencing and epigenome technologies: potential medical applications. Expert Rev. Med. Devices 7(6), 723-726 (2010).
    • (2010) Expert Rev. Med. Devices , vol.7 , Issue.6 , pp. 723-726
    • Roukos, D.H.1
  • 13
    • 84865812140 scopus 로고    scopus 로고
    • ENCODE project writes eulogy for junk DNA
    • Genomics
    • Pennisi E. Genomics. ENCODE project writes eulogy for junk DNA. Science 337(6099), 1159-1161 (2012).
    • (2012) Science , vol.337 , Issue.6099 , pp. 1159-1161
    • Pennisi, E.1
  • 14
    • 84865739425 scopus 로고    scopus 로고
    • Architecture of the human regulatory network derived from ENCODE data
    • Gerstein MB, Kundaje A, Hariharan M et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489(7414), 91-100 (2012).
    • (2012) Nature , vol.489 , Issue.7414 , pp. 91-100
    • Gerstein, M.B.1    Kundaje, A.2    Hariharan, M.3
  • 15
    • 77955591497 scopus 로고    scopus 로고
    • Complete genome sequencing and network modeling to overcome trastuzumab resistance
    • Roukos DH. Complete genome sequencing and network modeling to overcome trastuzumab resistance. Pharmacogenomics 11(8), 1039-1043 (2010).
    • (2010) Pharmacogenomics , vol.11 , Issue.8 , pp. 1039-1043
    • Roukos, D.H.1
  • 16
    • 79953066553 scopus 로고    scopus 로고
    • Trastuzumab and beyond: Sequencing cancer genomes and predicting molecular networks
    • Roukos DH. Trastuzumab and beyond: sequencing cancer genomes and predicting molecular networks. Pharmacogenomics J. 11(2), 81-92 (2011).
    • (2011) Pharmacogenomics J , vol.11 , Issue.2 , pp. 81-92
    • Roukos, D.H.1
  • 17
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: A network-based approach to human disease
    • Barabási AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nat. Rev. Genet. 12(1), 56-68 (2011).
    • (2011) Nat. Rev. Genet , vol.12 , Issue.1 , pp. 56-68
    • Barabási, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 18
    • 84866342003 scopus 로고    scopus 로고
    • Disrupting cancer cells' biocircuits with interactome-based drugs: Is 'clinical' innovation realistic?
    • Roukos DH. Disrupting cancer cells' biocircuits with interactome-based drugs: is 'clinical' innovation realistic? Expert Rev. Proteomics 9(4), 349-353 (2012).
    • (2012) Expert Rev. Proteomics , vol.9 , Issue.4 , pp. 349-353
    • Roukos, D.H.1
  • 19
    • 84861119813 scopus 로고    scopus 로고
    • Disrupting the networks of cancer
    • Camacho DF, Pienta KJ. Disrupting the networks of cancer. Clin. Cancer Res. 18(10), 2801-2808 (2012).
    • (2012) Clin. Cancer Res , vol.18 , Issue.10 , pp. 2801-2808
    • Camacho, D.F.1    Pienta, K.J.2
  • 20
    • 84861123691 scopus 로고    scopus 로고
    • Ten years of pathway analysis: Current approaches and outstanding challenges
    • Khatri P, Sirota M, Butte AJ. Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput. Biol. 8(2), e1002375 (2012).
    • (2012) PLoS Comput. Biol , vol.8 , Issue.2
    • Khatri, P.1    Sirota, M.2    Butte, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.