Comparison of compound administration methods in biochemical assays: Effects on apparent compound potency using either assay-ready compound plates or pin tool-delivered compounds

Journal of Biomolecular Screening

Volumn 18, Issue 1, 2013, Pages 14-25

  Smith, Thomas ^a   Ho, Pei I ^a   Yue, Kim ^a   Itkin, Zina ^a   MacDougall, Damien ^a   Paolucci, Mike ^a   Hill, Adam ^a   Auld, Douglas S ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

acoustic dispense; assay ready plates; compound; high throughput screening (HTS); microtiter plate; pin tool

Indexed keywords

COPOLYMER; CYCLIC OLEFIN COPOLYMER; LUCIFERASE; POLYSTYRENE; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FLUORESCENCE ANALYSIS; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY;

ADENOSINE TRIPHOSPHATE; BENZOTHIAZOLES; ENZYME ASSAYS; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; HYDROLYSIS; LUCIFERASES, FIREFLY; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; SOLUTIONS;

EID: 84871553866     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112455434     Document Type: Article

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