-
1
-
-
56349088740
-
Mutant SOD1 from spinal cord of G93A rats is destabilized and binds to inner mitochondrial membrane
-
Ahtoniemi T., Jaronen M., Keksa-Goldsteine V., Goldsteins G., Koistinaho J. Mutant SOD1 from spinal cord of G93A rats is destabilized and binds to inner mitochondrial membrane. Neurobiol Dis 2008, 32:479-485.
-
(2008)
Neurobiol Dis
, vol.32
, pp. 479-485
-
-
Ahtoniemi, T.1
Jaronen, M.2
Keksa-Goldsteine, V.3
Goldsteins, G.4
Koistinaho, J.5
-
2
-
-
75149155060
-
Oxidative stress in ALS: key role in motor neuron injury and therapeutic target
-
Barber S.C., Shaw P.J. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med 2009, 48:629-641.
-
(2009)
Free Radic Biol Med
, vol.48
, pp. 629-641
-
-
Barber, S.C.1
Shaw, P.J.2
-
3
-
-
34247882804
-
Human frataxin: iron and ferrochelatase binding surface
-
Bencze K.Z., Yoon T., Millan-Pacheco C., Bradley P.B., Pastor N., Cowan J.A., Stemmler T.L. Human frataxin: iron and ferrochelatase binding surface. Chem Commun (Camb) 2007, 14:1798-1800.
-
(2007)
Chem Commun (Camb)
, vol.14
, pp. 1798-1800
-
-
Bencze, K.Z.1
Yoon, T.2
Millan-Pacheco, C.3
Bradley, P.B.4
Pastor, N.5
Cowan, J.A.6
Stemmler, T.L.7
-
4
-
-
0042093555
-
Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine
-
Beretta S., Sala G., Mattavelli L., Ceresa C., Casciati A., Ferri A., Carri M.T., Ferrarese C. Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine. Neurobiol Dis 2003, 13:213-221.
-
(2003)
Neurobiol Dis
, vol.13
, pp. 213-221
-
-
Beretta, S.1
Sala, G.2
Mattavelli, L.3
Ceresa, C.4
Casciati, A.5
Ferri, A.6
Carri, M.T.7
Ferrarese, C.8
-
5
-
-
80051779168
-
Structure-function analysis of Friedreich's ataxia mutants reveals determinants of frataxin binding and activation of the Fe-S assembly complex
-
Bridwell-Rabb J., Winn A.M., Barondeau D.P. Structure-function analysis of Friedreich's ataxia mutants reveals determinants of frataxin binding and activation of the Fe-S assembly complex. Biochemistry 2011, 50:7265-7274.
-
(2011)
Biochemistry
, vol.50
, pp. 7265-7274
-
-
Bridwell-Rabb, J.1
Winn, A.M.2
Barondeau, D.P.3
-
6
-
-
0031559896
-
2+ concentration in transfected neuroblastoma SH-SY5Y cells
-
2+ concentration in transfected neuroblastoma SH-SY5Y cells. FEBS Lett 1997, 414:365-368.
-
(1997)
FEBS Lett
, vol.414
, pp. 365-368
-
-
Carri, M.T.1
Ferri, A.2
Battistoni, A.3
Famhy, L.4
Gabbianelli, R.5
Poccia, F.6
Rotilio, G.7
-
7
-
-
0042165931
-
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals
-
Carri M.T., Ferri A., Cozzolino M., Calabrese L., Rotilio G. Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Brain Res Bull 2003, 61:365-374.
-
(2003)
Brain Res Bull
, vol.61
, pp. 365-374
-
-
Carri, M.T.1
Ferri, A.2
Cozzolino, M.3
Calabrese, L.4
Rotilio, G.5
-
8
-
-
0036892743
-
Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases
-
Casciati A., Ferri A., Cozzolino M., Celsi F., Nencini M., Rotilio G., Carri M.T. Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases. J Neurochem 2002, 83:1019-1029.
-
(2002)
J Neurochem
, vol.83
, pp. 1019-1029
-
-
Casciati, A.1
Ferri, A.2
Cozzolino, M.3
Celsi, F.4
Nencini, M.5
Rotilio, G.6
Carri, M.T.7
-
9
-
-
80051635783
-
Iron-dependent functions of mitochondria - relation to neurodegeneration
-
Gille G., Reichmann H. Iron-dependent functions of mitochondria - relation to neurodegeneration. J Neural Transm 2011, 118:349-359.
-
(2011)
J Neural Transm
, vol.118
, pp. 349-359
-
-
Gille, G.1
Reichmann, H.2
-
10
-
-
43749099217
-
Deleterious role of superoxide dismutase in the mitochondrial intermembrane space
-
Goldsteins G., Keksa-Goldsteine V., Ahtoniemi T., Jaronen M., Arens E., Akerman K., Chan P.H., Koistinaho J. Deleterious role of superoxide dismutase in the mitochondrial intermembrane space. J Biol Chem 2008, 283:8446-8452.
-
(2008)
J Biol Chem
, vol.283
, pp. 8446-8452
-
-
Goldsteins, G.1
Keksa-Goldsteine, V.2
Ahtoniemi, T.3
Jaronen, M.4
Arens, E.5
Akerman, K.6
Chan, P.H.7
Koistinaho, J.8
-
11
-
-
79953785573
-
Management of respiratory symptoms in ALS
-
Hardiman O. Management of respiratory symptoms in ALS. J Neurol 2011, 258:359-365.
-
(2011)
J Neurol
, vol.258
, pp. 359-365
-
-
Hardiman, O.1
-
12
-
-
58849116869
-
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis
-
Jeong S.Y., Rathore K.I., Schulz K., Ponka P., Arosio P., David S. Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2009, 29:610-619.
-
(2009)
J Neurosci
, vol.29
, pp. 610-619
-
-
Jeong, S.Y.1
Rathore, K.I.2
Schulz, K.3
Ponka, P.4
Arosio, P.5
David, S.6
-
13
-
-
33751013740
-
Transgenic mouse models of amyotrophic lateral sclerosis
-
Julien J.P., Kriz J. Transgenic mouse models of amyotrophic lateral sclerosis. Biochim Biophys Acta 2006, 1762:1013-1024.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 1013-1024
-
-
Julien, J.P.1
Kriz, J.2
-
14
-
-
0032889677
-
Redox regulation of cellular signalling
-
Kamata H., Hirata H. Redox regulation of cellular signalling. Cell Signal 1999, 11:1-14.
-
(1999)
Cell Signal
, vol.11
, pp. 1-14
-
-
Kamata, H.1
Hirata, H.2
-
15
-
-
77951765013
-
Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species
-
Kayatekin C., Zitzewitz J.A., Matthews C.R. Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species. J Mol Biol 2010, 398:320-331.
-
(2010)
J Mol Biol
, vol.398
, pp. 320-331
-
-
Kayatekin, C.1
Zitzewitz, J.A.2
Matthews, C.R.3
-
16
-
-
79952814526
-
Friedreich's ataxia: pathology, pathogenesis, and molecular genetics
-
Koeppen A.H. Friedreich's ataxia: pathology, pathogenesis, and molecular genetics. J Neurol Sci 2011, 303:1-12.
-
(2011)
J Neurol Sci
, vol.303
, pp. 1-12
-
-
Koeppen, A.H.1
-
17
-
-
77952840568
-
Mapping of iron deposition in conjunction with assessment of nerve fiber tract integrity in amyotrophic lateral sclerosis
-
Langkammer C., Enzinger C., Quasthoff S., Grafenauer P., Soellinger M., Fazekas F., Ropele S. Mapping of iron deposition in conjunction with assessment of nerve fiber tract integrity in amyotrophic lateral sclerosis. J Magn Reson Imaging 2010, 31:1339-1345.
-
(2010)
J Magn Reson Imaging
, vol.31
, pp. 1339-1345
-
-
Langkammer, C.1
Enzinger, C.2
Quasthoff, S.3
Grafenauer, P.4
Soellinger, M.5
Fazekas, F.6
Ropele, S.7
-
18
-
-
82255171356
-
SOD1 transcriptional and posttranscriptional regulation and its potential implications in ALS
-
Milani P., Gagliardi S., Cova E., Cereda C. SOD1 transcriptional and posttranscriptional regulation and its potential implications in ALS. Neurol Res Int 2011, 458427.
-
(2011)
Neurol Res Int
, pp. 458427
-
-
Milani, P.1
Gagliardi, S.2
Cova, E.3
Cereda, C.4
-
19
-
-
33749657635
-
Transferrin localizes in Bunina bodies in amyotrophic lateral sclerosis
-
Mizuno Y., Amari M., Takatama M., Aizawa H., Mihara B., Okamoto K. Transferrin localizes in Bunina bodies in amyotrophic lateral sclerosis. Acta Neuropathol 2006, 112:597-603.
-
(2006)
Acta Neuropathol
, vol.112
, pp. 597-603
-
-
Mizuno, Y.1
Amari, M.2
Takatama, M.3
Aizawa, H.4
Mihara, B.5
Okamoto, K.6
-
20
-
-
0035397392
-
Ferritin and the response to oxidative stress
-
Orino K., Lehman L., Tsuji Y., Ayaki H., Torti S.V., Torti F.M. Ferritin and the response to oxidative stress. Biochem J 2001, 357:241-247.
-
(2001)
Biochem J
, vol.357
, pp. 241-247
-
-
Orino, K.1
Lehman, L.2
Tsuji, Y.3
Ayaki, H.4
Torti, S.V.5
Torti, F.M.6
-
21
-
-
0027502185
-
A mitogen-responsive promoter region that is synergistically activated through multiple signalling pathways
-
Ouyang Q., Bommakanti M., Miskimins W.K. A mitogen-responsive promoter region that is synergistically activated through multiple signalling pathways. Mol Cell Biol 1993, 13:1796-1804.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1796-1804
-
-
Ouyang, Q.1
Bommakanti, M.2
Miskimins, W.K.3
-
22
-
-
0033596121
-
Activators and target genes of Rel/NF-kappaB transcription factors
-
Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18:6853-6866.
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
23
-
-
79961126295
-
Respiration and ROS production in brain and spinal cord mitochondria of transgenic rats with mutant G93a Cu/Zn-superoxide dismutase gene
-
Panov A., Kubalik N., Zinchenko N., Hemendinger R., Dikalov S., Bonkovsky H.L. Respiration and ROS production in brain and spinal cord mitochondria of transgenic rats with mutant G93a Cu/Zn-superoxide dismutase gene. Neurobiol Dis 2011, 44:53-62.
-
(2011)
Neurobiol Dis
, vol.44
, pp. 53-62
-
-
Panov, A.1
Kubalik, N.2
Zinchenko, N.3
Hemendinger, R.4
Dikalov, S.5
Bonkovsky, H.L.6
-
24
-
-
32944457363
-
Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB
-
Paradkar P.N., Roth J.A. Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB. J Neurochem 2006, 96:1768-1777.
-
(2006)
J Neurochem
, vol.96
, pp. 1768-1777
-
-
Paradkar, P.N.1
Roth, J.A.2
-
25
-
-
59449083869
-
Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2
-
Paradkar P.N., Zumbrennen K.B., Paw B.H., Ward D.M., Kaplan J. Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2. Mol Cell Biol 2009, 29:1007-1016.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1007-1016
-
-
Paradkar, P.N.1
Zumbrennen, K.B.2
Paw, B.H.3
Ward, D.M.4
Kaplan, J.5
-
26
-
-
77951253200
-
The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia
-
Richardson D.R., Huang M.L., Whitnall M., Becker E.M., Ponka P., Suryo Rahmanto Y. The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia. J Mol Med (Berl) 2009, 88:323-329.
-
(2009)
J Mol Med (Berl)
, vol.88
, pp. 323-329
-
-
Richardson, D.R.1
Huang, M.L.2
Whitnall, M.3
Becker, E.M.4
Ponka, P.5
Suryo Rahmanto, Y.6
-
27
-
-
3242657100
-
Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells
-
Riemer J., Hoepken H.H., Czerwinska H., Robinson S.R., Dringen R. Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal Biochem 2004, 331:370-375.
-
(2004)
Anal Biochem
, vol.331
, pp. 370-375
-
-
Riemer, J.1
Hoepken, H.H.2
Czerwinska, H.3
Robinson, S.R.4
Dringen, R.5
-
28
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., Deng H.X. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
29
-
-
78951471098
-
Iron overload triggers redox-sensitive signals in human IMR-32 neuroblastoma cells
-
Salvador G.A., Oteiza P.I. Iron overload triggers redox-sensitive signals in human IMR-32 neuroblastoma cells. Neurotoxicology 2011, 32:75-82.
-
(2011)
Neurotoxicology
, vol.32
, pp. 75-82
-
-
Salvador, G.A.1
Oteiza, P.I.2
-
30
-
-
79551514731
-
Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex
-
Schmucker S., Martelli A., Colin F., Page A., Wattenhofer-Donze M., Reutenauer L., Puccio H. Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex. PLoS One 2011, 6:e16199.
-
(2011)
PLoS One
, vol.6
-
-
Schmucker, S.1
Martelli, A.2
Colin, F.3
Page, A.4
Wattenhofer-Donze, M.5
Reutenauer, L.6
Puccio, H.7
-
31
-
-
33644748145
-
Mitoferrin is essential for erythroid iron assimilation
-
Shaw G.C., Cope J.J., Li L., Corson K., Hersey C., Ackermann G.E., Gwynn B., Lambert A.J., Wingert R.A., Traver D., Trede N.S., Barut B.A., Zhou Y., Minet E., Donovan A., Brownlie A., Balzan R., Weiss M.J., Peters L.L., Kaplan J., Zon L.I., Paw B.H. Mitoferrin is essential for erythroid iron assimilation. Nature 2006, 440:96-100.
-
(2006)
Nature
, vol.440
, pp. 96-100
-
-
Shaw, G.C.1
Cope, J.J.2
Li, L.3
Corson, K.4
Hersey, C.5
Ackermann, G.E.6
Gwynn, B.7
Lambert, A.J.8
Wingert, R.A.9
Traver, D.10
Trede, N.S.11
Barut, B.A.12
Zhou, Y.13
Minet, E.14
Donovan, A.15
Brownlie, A.16
Balzan, R.17
Weiss, M.J.18
Peters, L.L.19
Kaplan, J.20
Zon, L.I.21
Paw, B.H.22
more..
-
32
-
-
42249102078
-
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
-
Turner B.J., Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 2008, 85:94-134.
-
(2008)
Prog Neurobiol
, vol.85
, pp. 94-134
-
-
Turner, B.J.1
Talbot, K.2
-
33
-
-
79958787596
-
Prevention of motor neuron degeneration by novel iron chelators in SOD1(G93A) transgenic mice of amyotrophic lateral sclerosis
-
Wang Q., Zhang X., Chen S., Zhang X., Zhang S., Youdium M., Le W. Prevention of motor neuron degeneration by novel iron chelators in SOD1(G93A) transgenic mice of amyotrophic lateral sclerosis. Neurodegener Dis 2011, 8:310-321.
-
(2011)
Neurodegener Dis
, vol.8
, pp. 310-321
-
-
Wang, Q.1
Zhang, X.2
Chen, S.3
Zhang, X.4
Zhang, S.5
Youdium, M.6
Le, W.7
|