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Volumn 45, Issue 11, 2012, Pages 647-652

Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves nrf2 downregulation

Author keywords

Chemoresistance; Clofarabine; Mesothelioma; Nrf2; Resveratrol

Indexed keywords

ADENINE NUCLEOTIDE; ANTINEOPLASTIC AGENT; ARABINONUCLEOSIDE; CLOFARABINE; HEME OXYGENASE 1; NFE2L2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RESVERATROL; SMALL INTERFERING RNA; STILBENE DERIVATIVE; TRANSCRIPTION FACTOR NRF2;

EID: 84871453477     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2012.45.11.111     Document Type: Article
Times cited : (24)

References (21)
  • 3
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler, T. W., Wakabayashi, N. and Biswal, S. (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47, 89-116.
    • (2007) Annu. Rev. Pharmacol. Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 4
    • 0242580049 scopus 로고    scopus 로고
    • Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
    • Zhang, D. D. and Hannink, M. (2003) Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol. Cell. Biol. 23, 8137-8151.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 8137-8151
    • Zhang, D.D.1    Hannink, M.2
  • 5
    • 77954351631 scopus 로고    scopus 로고
    • High levels of Nrf2 determine chemoresistance in type II endometrial cancer
    • Jiang, T., Chen, N., Zhao, F., Wang, X. J., Kong, B., Zheng, W. and Zhang, D. D. (2010) High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Res. 70, 5486-5496.
    • (2010) Cancer Res , vol.70 , pp. 5486-5496
    • Jiang, T.1    Chen, N.2    Zhao, F.3    Wang, X.J.4    Kong, B.5    Zheng, W.6    Zhang, D.D.7
  • 6
    • 76649089973 scopus 로고    scopus 로고
    • Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth
    • Zhang, P., Singh, A., Yegnasubramanian, S., Esopi, D., Kombairaju, P., Bodas, M., Wu, H., Bova, S. G. and Biswal, S. (2010) Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Mol. Cancer Ther. 9, 336-346.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 336-346
    • Zhang, P.1    Singh, A.2    Yegnasubramanian, S.3    Esopi, D.4    Ombairaju, P.5    Bodas, M.6    Wu, H.7    Bova, S.G.8    Biswal, S.9
  • 7
    • 46649112474 scopus 로고    scopus 로고
    • Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells
    • Kim, S. K., Yang, J. W., Kim, M. R., Roh, S. H., Kim, H. G., Lee, K. Y., Jeong, H. G. and Kang, K. W. (2008) Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells. Free Radic. Biol. Med. 45, 537-546.
    • (2008) Free Radic. Biol. Med , vol.45 , pp. 537-546
    • Kim, S.K.1    Yang, J.W.2    Kim, M.R.3    Roh, S.H.4    Kim, H.G.5    Lee, K.Y.6    Jeong, H.G.7    Kang, K.W.8
  • 8
    • 84855218747 scopus 로고    scopus 로고
    • Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells
    • Lee, Y. J., Jeong, H. Y., Kim, Y. B., Lee, Y. J., Won, S. Y., Shim, J. H., Cho, M. K., Nam, H. S. and Lee, S. H. (2012) Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells. Food Chem. Toxicol. 50, 116-123.
    • (2012) Food Chem. Toxicol , vol.50 , pp. 116-123
    • Lee, Y.J.1    Jeong, H.Y.2    Kim, Y.B.3    Lee, Y.J.4    Won, S.Y.5    Shim, J.H.6    Cho, M.K.7    Nam, H.S.8    Lee, S.H.9
  • 12
    • 80052079930 scopus 로고    scopus 로고
    • Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cells
    • Santandreu, F. M., Valle, A., Oliver, J. and Roca, P. (2011) Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cells. Cell Physiol. Biochem. 28, 219-228.
    • (2011) Cell Physiol. Biochem , vol.28 , pp. 219-228
    • Santandeu, F.M.1    Valle, A.2    Oliver, J.3    Roca, P.4
  • 13
    • 54049147251 scopus 로고    scopus 로고
    • Reversal effect of resveratrol on multidrug resistance in KBv200 cell line
    • Quan, F., Pan, C., Ma, Q., Zhang, S. and Yan, L. (2008) Reversal effect of resveratrol on multidrug resistance in KBv200 cell line. Biomed. Pharmacother. 62, 622-629.
    • (2008) Biomed. Pharmacother , vol.62 , pp. 622-629
    • Quan, F.1    Pan, C.2    Ma, Q.3    Zhang, S.4    Yan, L.5
  • 15
    • 77956258890 scopus 로고    scopus 로고
    • Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents
    • Frampton, G. A., Lazcano, E. A., Li, H., Mohamad, A. and DeMorrow, S. (2010) Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents. Lab. Invest. 90, 1325-1338.
    • (2010) Lab. Invest , vol.90 , pp. 1325-1338
    • Frampton, G.A.1    Lazcano, E.A.2    Li, H.3    Mohamad, A.4    Demorrow, S.5
  • 18
    • 1542335553 scopus 로고    scopus 로고
    • Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3 kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical
    • Martin, D., Rojo, A. I., Salinas, M., Diaz, R., Gallardo, G., Alam, J., De Galarreta, C. M. and Cuadrado, A. (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3 kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical, carnosol. J. Biol. Chem. 279, 8919-8929.
    • (2004) carnosol. J. Biol. Chem , vol.279 , pp. 8919-8929
    • Martin, D.1    Rojo, A.I.2    Salinas, M.3    Diaz, R.4    Gallardo, G.5    Alam, J.6    Galarreta, D.C.M.7    Cuadrado, A.8
  • 19
    • 61449208761 scopus 로고    scopus 로고
    • Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes
    • Reisman, S. A., Aleksunes, L. M. and Klaassen, C. D. (2009) Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes. Biochem. Pharmacol. 77, 1273-1282.
    • (2009) Biochem. Pharmacol , vol.77 , pp. 1273-1282
    • Reisman, S.A.1    Aleksunes, L.M.2    Klaassen, C.D.3
  • 20
    • 24944486664 scopus 로고    scopus 로고
    • Resistance to paclitaxel is proportional to cellular total antioxidant capacity
    • Ramanathan, B., Jan, K. Y., Chen, C. H., Hour, T. C., Yu, H. J. and Pu, Y. S. (2005) Resistance to paclitaxel is proportional to cellular total antioxidant capacity. Cancer Res. 65, 8455-8460.
    • (2005) Cancer Res , vol.65 , pp. 8455-8460
    • Ramanathan, B.1    Jan, K.Y.2    Chen, C.H.3    Hour, T.C.4    Yu, H.J.5    Pu, Y.S.6
  • 21
    • 3042689052 scopus 로고    scopus 로고
    • Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung
    • Kinnula, V. L., Pääkkö, P. and Soini, Y. (2004) Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung. FEBS Lett. 569, 1-6.
    • (2004) FEBS Lett , vol.569 , pp. 1-6
    • Kinnula, V.L.1    Pääkkö, P.2    Soini, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.