Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein Kinase inhibitors in vitro

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Pédeboscq, Stéphane ^a,b   Rey, Christophe ^a   Petit, Muriel ^c   Harpey, Catherine ^d   de Giorgi, Francesca ^a,c   Ichas, François ^a,c   Lartigue, Lydia ^a  

^a INSERM   (France)

^b HÔPITAL SAINT ANDRÉ   (France)

^c FLUOFARMA   (France)

^d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; IMATINIB; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NILOTINIB; PROTEIN KINASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG EFFICACY; HUMAN; HUMAN CELL; PHARMACOLOGICAL BLOCKING; PROTEIN CLEAVAGE;

EID: 84871447012     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036811     Document Type: Article

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