Cyclic tensile loading regulates human mesenchymal stem cell differentiation into neuron-like phenotype

Journal of Tissue Engineering and Regenerative Medicine

Volumn 6, Issue SUPPL. 3, 2012, Pages

  Leong, Wen Shing ^a,b   Wu, Shu Cheng ^a,c   Pal, Mintu ^a   Tay, Chor Yong ^a   Yu, Haiyang ^a   Li, Huaqiong ^a   Tan, Lay Poh ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b Republic Polytechnic   (Singapore)

^c DEPARTMENT OF ELECTRONICS AND COMPUTER ENGINEERING   (Singapore)

Author keywords

Cyclic tensile loading; Human mesenchymal stem cells; Microfilaments; Neuron like differentiation; Poly( caprolactone); Rho GTPases

Indexed keywords

CELL CULTURE; FLOWCHARTING; GENE EXPRESSION; LOADING; PROTEINS; STEM CELLS; TENSILE STRESS;

GTPASE ACTIVITY; HUMAN MESENCHYMAL STEM CELLS; MECHANICAL LOADING; MESENCHYMAL STEM CELL; MICROFILAMENTS; NEURON-LIKE DIFFERENTIATION; POLY(Ε CAPROLACTONE); POLY(Ε-CAPROLACTONE); RHO GTPASES; STEM CELL DIFFERENTIATION;

NEURONS;

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; NESTIN; POLYCAPROLACTONE; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; BIOREACTOR; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL STRUCTURE; CONTROLLED STUDY; CYCLIC TENSILE LOADING; ENZYME ACTIVITY; ENZYME INHIBITION; FILOPODIUM; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LOADING TEST; MECHANICAL STIMULATION; MESENCHYMAL STEM CELL; MICROFILAMENT; NERVE CELL; NERVE CELL DIFFERENTIATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TENSILE STRENGTH; TISSUE SPECIFICITY; UPREGULATION;

EID: 84871436605     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1548     Document Type: Article

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