Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4-NFκB signalling

European Journal of Cancer

Volumn 49, Issue 1, 2013, Pages 254-263

  Scarpa, Marco ^a   Cardin, Romilda ^b   Bortolami, Marina ^b   Kotsafti, Andromachi ^a   Scarpa, Maria Cristina ^b   Pozza, Anna ^b   Maran, Giorgia ^b   Picciocchi, Marika ^b   Ruffolo, Cesare ^c   D'Incà, Renata ^b   Sturniolo, Giacomo C ^b   Castagliuolo, Ignazio ^b   Castoro, Carlo ^a   Angriman, Imerio ^b  

^a VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c OSPEDALE CA FONCELLO   (Italy)

Author keywords

8 OHdG; CD80; Colonic cancerogenesis; Colorectal cancer; Immunosurveillance; NF B; TLR4; Ulcerative colitis

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; B7 ANTIGEN; BETA CATENIN; CD86 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN P53; TOLL LIKE RECEPTOR 4;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CANCER INCIDENCE; CANCER SCREENING; COLON ADENOMA; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; COLON RESECTION; COLONOSCOPY; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE DURATION; DNA BINDING; DNA DAMAGE; DYSPLASIA; EPITHELIUM CELL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; LAMINA PROPRIA; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM RESECTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ULCERATIVE COLITIS;

ADENOCARCINOMA; ADENOMA; ADULT; ANTIGENS, CD80; CELL TRANSFORMATION, NEOPLASTIC; COLITIS, ULCERATIVE; COLONIC NEOPLASMS; DNA DAMAGE; FEMALE; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; NF-KAPPA B; OXIDATIVE STRESS; PRECANCEROUS CONDITIONS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84871426580     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.05.015     Document Type: Article

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