A versatile proline/alanine transporter in the unicellular pathogen Leishmania donovani regulates amino acid homoeostasis and osmotic stress responses

Biochemical Journal

Volumn 449, Issue 2, 2013, Pages 555-566

  Inbar, Ehud ^a,c   Schlisselberg, Doreen ^a   Suter Grotemeyer, Marianne ^b   Rentsch, Doris ^b   Zilberstein, Dan ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b UNIVERSITY OF BERN   (Switzerland)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Amino acid transport; Leishmania; Osmoregulation; Parasitic protozoa

Indexed keywords

ALANINE; AMINO ACID TRANSPORTER; MESSENGER RNA; PROLINE;

AMINO ACID TRANSPORT; ARTICLE; CARBON SOURCE; CELL MEMBRANE; CELL SWELLING; CELL VOLUME; CHROMOSOME 10; DNA FLANKING REGION; ESCHERICHIA COLI; EXPRESSION VECTOR; HOMEOSTASIS; HOST PATHOGEN INTERACTION; HYPOOSMOTIC STRESS; IMMUNOFLUORESCENCE MICROSCOPY; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; NONHUMAN; NULL CELL; OSMOREGULATION; OSMOTIC STRESS; PARASITISM; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET IRRADIATION;

ADAPTATION, PHYSIOLOGICAL; ALANINE; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; AMINO ACIDS; ARGININE; BIOLOGICAL TRANSPORT; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL MEMBRANE; GENE EXPRESSION; GENETIC COMPLEMENTATION TEST; GLUTAMIC ACID; HOMEOSTASIS; LEISHMANIA DONOVANI; MICROSCOPY, FLUORESCENCE; MUTATION; OSMOTIC PRESSURE; PROLINE; PROTOZOAN PROTEINS; SACCHAROMYCES CEREVISIAE; STRESS, PHYSIOLOGICAL;

HEXAPODA; LEISHMANIA DONOVANI; PROTOZOA; TRYPANOSOMATIDAE;

EID: 84871412936     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121262     Document Type: Article

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