Poloxamer-188 attenuates TBI-induced blood-brain barrier damage leading to decreased brain edema and reduced cellular death

Neurochemical Research

Volumn 37, Issue 12, 2012, Pages 2856-2867

  Bao, Hai Jun ^a   Wang, Tao ^a   Zhang, Ming Yang ^a,b   Liu, Ran ^a   Dai, Ding Kun ^a   Wang, Yao Qi ^a   Wang, Long ^a   Zhang, Lu ^a   Gao, Yu Zhen ^a   Qin, Zheng Hong ^a   Chen, Xi Ping ^a   Tao, Lu Yang ^a  

^a SOOCHOW UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Brain edema; Neurovascular unit; Poloxamer 188; Traumatic brain injury

Indexed keywords

AQUAPORIN 4; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; POLOXAMER; PROTEIN BAX; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER DAMAGE; BRAIN DAMAGE; BRAIN EDEMA; CEREBRAL WATER CONTENT; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MALE; MOTOR PERFORMANCE; MOUSE; NERVE CELL NECROSIS; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRAUMATIC BRAIN INJURY; UPREGULATION; WATER CONTENT; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN EDEMA; BRAIN INJURIES; CELL DEATH; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MAZE LEARNING; MICE; POLOXAMER; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MUS;

EID: 84871401547     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0880-4     Document Type: Article

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