G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 51, 2012, Pages

  O'Neill, Patrick R ^a   Karunarathne, W K Ajith ^a   Kalyanaraman, Vani ^a   Silvius, John R ^b   Gautama, N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

G protein coupled receptors; Protein membrane interaction; Spatio temporal dynamics

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISSOCIATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR MEMBRANE; INTRACELLULAR SIGNALING; MATHEMATICAL MODEL; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN TRANSPORT;

AMINO ACID SEQUENCE; CELL MEMBRANE; DIMERIZATION; FLUORESCENT DYES; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR MEMBRANES; KINETICS; LIPIDS; MICROSCOPY, FLUORESCENCE; MODELS, THEORETICAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 84871373858     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205345109     Document Type: Article

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