Characterisation of a neural teratogenicity assay based on human escs differentiation following exposure to valproic acid

Current Medicinal Chemistry

Volumn 19, Issue 35, 2012, Pages 6065-6071

  Colleoni, S ^a   Galli, C ^a,c,d   Gaspar, J A ^b   Meganathan, K ^b   Jagtap, S ^b   Hescheler, J ^b   Sachinidis, A ^b   Lazzari, G ^a,d  

^a Laboratory of Reproductive Technologies   (Italy)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d Fondazione Avantea   (Italy)

Author keywords

Alternative in vitro test; Early neural toxicity; Embryonic stem cells; Neural development; Neural tube; Prenatal developmental toxicity; Teratogenicity assay; Valproic acid

Indexed keywords

TRANSCRIPTOME; VALPROIC ACID;

ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CYTOTOXICITY; DRUG EXPOSURE; EMBRYONIC STEM CELL; GASTRULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; NERVE CELL; NEURAL TERATOGENICITY; NEURAL TUBE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOGENICITY; TRANSCRIPTOMICS;

CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; NEURONS; TERATOGENS; VALPROIC ACID;

EID: 84871327000     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712804485926     Document Type: Article

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