Association of the neuropilin-2 (NRP2) gene polymorphisms with autism in Chinese Han population

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 144, Issue 4, 2007, Pages 492-495

  Wu, Suping ^a   Yue, Weihua ^a   Jia, Meixiang ^a   Ruan, Yan ^a   Lu, Tianlan ^a   Gong, Xiaohong ^a   Shuang, Mei ^a   Liu, Jing ^a   Yang, Xiaoling ^a   Zhang, Dai ^a  

^a PEKING UNIVERSITY SIXTH HOSPITAL   (China)

Author keywords

Haplotype; Single nucleotide polymorphism (SNP); Transmission disequilibrium test (TDT)

Indexed keywords

NEUROPILIN 2;

ADOLESCENT; ARTICLE; AUTISM; CHILD; CHINESE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NRP2 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; AUTISTIC DISORDER; CHILD; CHILD, PRESCHOOL; CHINA; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; NEUROPILIN-2; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 34250878459     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30495     Document Type: Article

References (31)

1. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders, 4th edition. Washington, DC: American Psychiatric Press.
2. Bailey A, Luthert P, Dean A, Harding B, Janota I, Montgomery M, Rutter M, Lantos P. 1998. A clinicopathological study of autism. Brain 121(Pt 5):889-905.
3. Buxbaum JD, Silverman JM, Smith CJ, Kilifarski M, Reichert J, Hollander E, Lawlor BA, Fitzgerald M, Greenberg DA, Davis KL. 2001. Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity. Am J Hum Genet 68(6):1514-1520.
4. Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chedotal A, Tessier-Lavigne M. 2000. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 25(1):43-56.
5. Collaborative Linkage Study of Autism (CLSA). 2001. An autosomal genomic screen for autism. Am J Med Genet 105:609-615.
6. Courchesne E. 1997. Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. Curr Opin Neurobiol 7(2):269-278.
7. Dawson G, Webb SJ, McPartland J. 2005. Understanding the nature of face processing impairment in autism: Insights from behavioral and electrophysiological studies. Dev Neuropsychol 27(3):403-424.
8. Fatemi SH, Snow AV, Stary JM, Araghi-Niknam M, Reutiman TJ, Lee S, Brooks AI, Pearce DA. 2005. Reelin signaling is impaired in autism. Biol Psychiatry 57(7):777-787.
9. Folstein SE, Rosen-Sheidley B. 2001. Genetics of autism: Complex aetiology for a heterogeneous disorder. Nat Rev Genet 2(12):943-955.
10. Frankenburg WK, Dodds JB. 1967. The Denver Developmental Screening Test. J Pediatr 71(2):181-191.
11. Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, et al. 2000. Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron 25(1):29-41.
12. International Molecular Genetic Study of Autism Consortium (IMGSAC). 1998. A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Hum Mol Genet 7:571-578.
13. International Molecular Genetic Study of Autism Consortium (IMGSAC). 2001. A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p. Am J Hum Genet 69:570-581.
14. Krug DA, Arick J, Almond P. 1980. Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior. J Child Psychol Psychiatry 21(3):221-229.
15. Liu J, Nyholt DR, Magnussen P, Parano E, Pavone P, Geschwind D, Lord C, Iversen P, Hoh J, Ott J, et al. 2001. A genomewide screen for autism susceptibility loci. Am J Hum Genet 69(2):327-340.
16. Lord C, Cook EH, Leventhal BL, Amaral DG. 2000. Autism spectrum disorders. Neuron 28(2):355-363.
17. Ma DQ, Whitehead PL, Menold MM, Martin ER, Ashley-Koch AE, Mei H, Ritchie MD, Delong GR, Abramson RK, Wright HH, et al. 2005. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. Am J Hum Genet 77(3):377-388.
18. Marin O, Yaron A, Bagri A, Tessier-Lavigne M, Rubenstein JL. 2001. Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions. Science 293(5531):872-875.
19. Menold MM, Shao Y, Wolpert CM, Donnelly SL, Raiford KL, Martin ER, Ravan SA, Abramson RK, Wright HH, Delong GR, et al. 2001. Association analysis of chromosome 15 gabaa receptor subunit genes in autistic disorder. J Neurogenet 15(3-4):245-259.
20. Miller MT, Stromland K, Ventura L, Johansson M, Bandim JM, Gillberg C. 2005. Autism associated with conditions characterized by developmental errors in early embryogenesis: A mini review. Int J Dev Neurosci 23(2-3):201-219.
21. Nakamura F, Goshima Y. 2002. Structural and functional relation of neuropilins. Adv Exp Med Biol 515:55-69.
22. Persico AM, D'Agruma L, Maiorano N, Totaro A, Militerni R, Bravaccio C, Wassink TH, Schneider C, Melmed R, Trillo S, et al. 2001. Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder. Mol Psychiatry 6(2):150-159.
23. Philippe A, Martinez M, Guilloud-Bataille M, Gillberg C, Rastam M, Sponheim E, Coleman M, Zappella M, Aschauer H, Van Maldergem L, et al. 1999. Genome-wide scan for autism susceptibility genes. Paris Autism Research International Sibpair Study. Hum Mol Genet 8(5):805-812.
24. Pickles A, Bolton P, Macdonald H, Bailey A, Le Couteur A, Sim CH, Rutter M. 1995. Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: A twin and family history study of autism. Am J Hum Genet 57(3):717-726.
25. Rossignol M, Beggs AH, Pierce EA, Klagsbrun M. 1999. Human neuropilin-1 and neuropilin-2 map to 10p12 and 2q34, respectively. Genomics 57(3):459-460.
26. Schopler E, Reichler RJ, DeVellis RF, Daly K. 1980. Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS). J Autism Dev Disord 10(1):91-103.
27. Shao Y, Wolpert CM, Raiford KL, Menold MM, Donnelly SL, Ravan SA, Bass MP, McClain C, von Wendt L, Vance JM, et al. 2002. Genomic screen and follow-up analysis for autistic disorder. Am J Med Genet 114(1):99-105.
28. Skoyles JR. 2002. Is autism due to cerebral-cerebellum disconnection? Med Hypotheses 58(4):332-336.
29. Teitelbaum P, Teitelbaum O, Nye J, Fryman J, Maurer RG. 1998. Movement analysis in infancy may be useful for early diagnosis of autism. Proc Natl Acad Sci USA 95(23):13982-13987.
30. Veenstra-VanderWeele J, Cook EH Jr. 2004. Molecular genetics of autism spectrum disorder. Mol Psychiatry 9(9):819-832.
31. Wechsler D. 1991. Manual for the Wechsler Intelligence Scale for Children, 3rd ed. New York: Psychological Corp.