Cyclin D1 degradation and p21 induction contribute to growth inhibition of colorectal cancer cells induced by epigallocatechin-3-gallate

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 12, 2012, Pages 2051-2060

  Zhang, Xiaobo ^a,b   Min, Kyung Won ^b   Wimalasena, Jay ^c   Baek, Seung Joon ^b  

^a NORTHWEST A F UNIVERSITY   (China)

^b UNIVERSITY OF TENNESSEE   (United States)

^c UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

Author keywords

Colorectal cancer; Cyclin D1; EGCG; P21; Proteasome

Indexed keywords

CASPASE 3; CASPASE 7; CYCLIN D1; CYCLINE; EPIGALLOCATECHIN GALLATE; I KAPPA B KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; THREONINE;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE REGULATION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION;

APOPTOSIS; CACO-2 CELLS; CASPASE 3; CASPASE 7; CATECHIN; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; HCT116 CELLS; HT29 CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; SIGNAL TRANSDUCTION; UBIQUITINATION; UP-REGULATION;

EID: 84871315966     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1276-1     Document Type: Article

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