Association between 9p21.3 genomic markers and coronary artery disease in East Asians: A meta-analysis involving 9,813 cases and 10,710 controls

Molecular Biology Reports

Volumn 40, Issue 1, 2013, Pages 337-343

  Guo, Jin ^a   Li, Wei ^a   Wu, Zhenqiang ^b   Cheng, Xiaoru ^a   Wang, Yang ^a   Chen, Tao ^a  

^a FUWAI HOSPITAL   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

China; Coronary artery disease; East Asian; Genetics; Meta analysis

Indexed keywords

ALLELE; CHINESE; CHROMOSOME 9P; CORONARY ARTERY DISEASE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HEART INFARCTION; HUMAN; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 9; CORONARY ARTERY DISEASE; GENETIC HETEROGENEITY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS;

EID: 84871315349     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2066-1     Document Type: Review

References (30)

1. Teo KK, Liu L, Chow CK et al (2009) Potentially modifiable risk factors associated with myocardial infarction in China: the INTERHEART China study. Heart 95:1857-1864
2. Glenn E, Palomaki, Stephanie Melillo, Linda A (2010) Bradley association between 9p21 genomic markers and heart disease: a meta-analysis. JAMA 303:605-656
3. Hobbs FD (2004) Cardiovascular disease: different strategies for primary and secondary prevention. Heart 90:1217-1223
4. van Wyk JT, van Wijk MA, Sturkenboom MC, Moorman PW, van der Lei J (2005) Identification of the four conventional cardiovascular disease risk factors by Dutch general practitioners. Chest 128:2521-2527
5. Wang TJ, Gona P, Larson MG et al (2006) Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med 355:2631-2639
6. Helgadottir A, Thorleifsson G, Manolescu A et al (2007) A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316:1491-1493
7. McPherson R, Pertsemlidis A, Kavaslar N et al (2007) A common allele on chromosome 9 associated with coronary heart disease. Science 316:1488-1491
8. Xie F, Chu X, Wu H et al (2011) Replication of putative susceptibility loci from genome-wide association studies associated with coronary atherosclerosis in Chinese Han population. Plos One 6:e20833
9. Wang W, Peng W, Lu L et al (2011) Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients. Chin Med J 124:66-71
10. Ding H, Xu Y, Wang X et al (2009) 9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population. Circ Cardiovasc Genet 2:338-346
11. Peng W, Lu L, Zhang Q et al (2009) Chromosome 9p21 polymorphism is associated with myocardial infarction but not with clinical outcome in Han Chinese. Clin Chem Lab Med 47:917-922
12. Zhang Q, Wang X, Cheng S et al (2009) Three SNPs on chromosome 9p21 confer increased risk of myocardial infarction in Chinese subjects. Atherosclerosis 207:26-28
13. Zhou L, Zhang X, He M et al (2008) Associations between single nucleotide polymorphisms on chromosome 9p21 and risk of coronary heart disease in Chinese Han population. Arterioscler Thromb Vasc Biol 28:2085-2089
14. Hiura Y, Fukushima Y, Yuno M et al (2008) Validation of the association of genetic variants on chromosome 9p21 and 1q41 with myocardial infarction in a Japanese population. Circ J 72:1213-1217
15. Chen Z, Qian Q, Ma G et al (2009) A common variant on chromosome 9p21 affects the risk of early-onset coronary artery disease. Mol Biol Rep 36:889-893
16. Hinohara K, Nakajima T, Takahashi M et al (2008) Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations. J Hum Genet 53:357-359
17. Shen G, Li L, Rao S et al (2008) Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease. Arterioscler Thromb Vasc Biol 28:360-365
18. Qiu Z, Zhang Y, Gao S et al (2011) SusceptibiHty study of 9p21 polymophism in patients with coronary heart disease in Chinese Han population. Geriatr Health Care 17:21-24
19. Guo J, Li W, Liu X et al (2011) Association study of single-nucleotide polymorphisms on chromosome 1p13 and 9p21 with Acute myocardial infarction (AMI) in a Chinese population: the Interheart China Study. Acad J Second Mil Med University 32:822-829
20. Palomaki G, Melillo S, Bradley L (2010) Association between 9p21 genomic markers and heart disease. JAMA 303:7
21. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR (2009) Introduction to meta-analysis. Wiley, West Sussex
22. Anderson JL, Horne BD, Kolek MJ et al (2008) Genetic variation at the 9p21 locus predicts angiographic coronary artery disease prevalence but not extent and has clinical utility. Am Heart J 156:1155-1162 e2
23. Brautbar A, Ballantyne CM, Lawson K et al (2009) Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the atherosclerosis risk in communities study. Circ Cardiovasc Genet 2:279-285
24. Preuss M, König R, Thompson R et al (2010) Design of the coronary artery disease genome-wide replication and meta-analysis (CARDIoGRAM) study: a genome-wide association meta-analysis involving more than 22,000 cases and 60,000 controls. Circ Cardiovasc Genet 3:475-483
25. Schunkert H, GoÂ̈tz A, Braund P et al (2008) Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 117:1675-1684
26. Lowe SW, Sherr CJ (2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 13:77-83
27. Hannon GJ, Beach D (1994) p15INK4B is a potential effector of TGF-betainduced cell cycle arrest. Nature 371:257-261
28. Kalinina N, Agrotis A, Antropova Y et al (2004) Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions. Arterioscler Thromb Vasc Biol 24:1391-1396
29. Saxena R, Voight BF, Lyssenko V et al (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341
30. Scott LJ, Mohlke KL, Bonnycastle LL et al (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345