Epigenetic Changes in Basal Cell Carcinoma Affect SHH and WNT Signaling Components

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Brinkhuizen, Tjinta ^a,b   van den Hurk, Karin ^a,b   Winnepenninckx, Véronique J L ^a,b   de Hoon, Joep P ^a,b   van Marion, Ariënne M ^c   Veeck, Jürgen ^a,b,d   van Engeland, Manon ^a,b   van Steensel, Maurice A M ^a,b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c VIECURI MEDICAL CENTER   (Netherlands)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; MESSENGER RNA; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; SECRETED FRIZZLED RELATED PROTEIN 5; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

ADULT; APC GENE; ARTICLE; BASAL CELL CARCINOMA; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RASSF1A GENE; SFRP5 GENE; SHH GENE; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; WNT GENE;

AGED; CARCINOMA, BASAL CELL; CASE-CONTROL STUDIES; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; MALE; PROMOTER REGIONS, GENETIC; SKIN; SKIN NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; WNT PROTEINS;

ERINACEIDAE;

EID: 84871278776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051710     Document Type: Article

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