From popular use to pharmacological validation: A study of the anti-inflammatory, anti-nociceptive and healing effects of Chenopodium ambrosioides extract

Journal of Ethnopharmacology

Volumn 145, Issue 1, 2013, Pages 127-138

  Trivellatograssi, Liliane ^a   Malheiros, Angela ^a   Meyre Silva, Christiane ^a   Da Silva Buss, Ziliani ^b   Monguilhott, Eduardo Dalmarco ^b   Fröde, Tânia S ^b   Da Silva, Kathryn Ana Bortolini Simão ^a   De Souza, Márcia Maria ^a  

^a UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

^b Department of Clinical Analyses   (Brazil)

Author keywords

Anti inflammatory; Anti nociceptive; Chenopodium ambrosioides; Pain; Wound healing

Indexed keywords

ADENOSINE DEAMINASE; ALCOHOL; ARACHIDONIC ACID; BRADYKININ; CAPSAICIN; CHENOPODIUM AMBROSIOIDES EXTRACT; CROTON OIL; FORMALDEHYDE; INDOMETACIN; MYELOPEROXIDASE; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; EAR EDEMA; ENZYME ACTIVITY; LEUKOCYTE; MALE; MOTOR PERFORMANCE; MOUSE; NEUTROPHIL; NONHUMAN; PAW EDEMA; PLANT LEAF; WOUND HEALING;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BODY TEMPERATURE; CHENOPODIUM AMBROSIOIDES; DISEASE MODELS, ANIMAL; EDEMA; ETHANOL; INFLAMMATION MEDIATORS; MALE; MICE; MONOTERPENES; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PLEURISY; ROTAROD PERFORMANCE TEST; WOUND HEALING;

ANIMALIA; CHENOPODIUM AMBROSIOIDES; MUS; RATTUS;

EID: 84871276855     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.040     Document Type: Article

References (47)

1. S.B. Abramson Nitric oxide in inflammation and pain associated with osteoarthritis Arthritis Research Therapy 10 2008 1 7
2. P. Alfonsi, F. Adam, A. Passard, B. Guignard, D.I. Sessler, and M. Chauvin Nefopam, a non-sedative benzoxazocineanalgesic, selectively reduces the shivering threshold in unanesthetizedsubjects Anesthesiology 100 2004 37 43
3. I. Andújar, M.C. Recio, T. Bacelli, R.M. Giner, and J.L. Ríos Shikonin reduces oedema induced by phorbol ester by interfering with IkBa degradation thus inhibiting translocation of NF-kB to the nucleus British Journal of Pharmacology 160 2010 376 388
4. M.A. Ansonoff, J. Zhang, T. Czyzyk, R.B. Rothman, J. Stewart, H. Xu, J. Zjwiony, D.J. Siebert, F. Yang, B.L. Roth, and J.E. Pintar Antinociceptive and hypothermic effects of salvinorin A are abolished in a novel strain of kappa-opioid receptor-1 knockout mice Journal of Pharmacology and Experimental Therapeutics 318 2006 641 648
5. L. Antonioli, M. Fornai, R. Colucci, N. Ghisu, M. Tuccori, M. Del Tacca, and C. Blandizzi Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases Inflammatory Bowel Diseases 14 2008 566 574
6. M. Bhatia Hydrogen sulfide and substance P in inflammation Antioxidants & Redox Signaling 12 2010 1191 1202
7. Brasil, 2008. Ministério Da Saúde, Secretaria de Ciências, Tecnologia e Insumos Estratégicos. Portaria Interministerial n° 2960 em 9 de dezembro de 2008. Publica Programa de Nacional de Plantas Medicinais e Fitoterápicos. Diário Oficial da União, 10 de dez.
8. T.C.P.M. Busnardo, C. Padoani, T.C. Mora, M.W. Biavatti, T.S. Frode, C. Burger, V.D. Claudino, E.M. Dalmarco, and M.M. Souza Anti-inflammatory evaluation of Coronopus didymus in the pleurisy and paw oedema models in mice Journal of Ethnopharmacology 128 2010 519 525
9. J.F. Cailhier, D.A. Sawatzky, T. Kipari, K. Houlberg, D. Walbaum, S. Watson, R.A. Lang, S. Clay, D. Kluth, J. Savill, and J. Hugues Resident pleural macrophages are key orchestrators of neutrophil recruitment in pleural inflammation American Journal of Respiratory and Critical Care Medicine 173 2006 540 547
10. J.B. Calixto, R. Medeiros, E.S. Fernandes, J. Ferreira, D.A. Cabrini, and M.M. Campos Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes British Journal of Pharmacology 143 2004 803 818
11. J.F. Cavalli, F. Tomi, A.F. Bernardini, and J. Casanova Combined analysis of the essential oil of Chenopodium ambrosioides by GC, GC-MS and 13C NMR spectroscopy: quantitative determination of ascaridole, a heatsensitive compound Phytochemical Analysis 15 2004 275 279
12. S.E. Cross, M.J. Thompson, and M.S. Roberts Distribution of systemically administered ampicillin, benzylpenicillin, and flucloxacillin in excisional wounds in diabetic and normal rats and effects of local topical vasodilator treatment Antimicrobial Agents Chemotherapy 40 1996 1703 1710
13. E. Dalmarco, T.S. Fröde, and Y.S. Medeiros Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy Mediators of Inflammation 11 2002 299 306
14. Dembitsky, V.; Shkrob, I.; Hanus, L.O.; 2008. Ascaridole and related peroxides from the genus Chenopodium. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 152, 209-215.
15. Q. Delespaul, V.G. De Billerbeck, C.G. Roques, and G. Michel The antifungal activity of oils as determinated by different screening methods Journal of Essential Oil Research 12 2000 256 266
16. M. Déciga-Campos, J.F. Palacios-Espinosa, A. Reyes-Ramírez, and R. Mata Antinociceptive and anti-infammatory effects of compounds isolated from Scaphyglottislivida and Maxillariadensa Journal of Ethnopharmacology 114 2007 161 168
17. N.W. Dunham, and T.S. Miya A note on a simple apparatus for detecting neurological deficit in rats and mice Journal of the American Pharmaceutical Association 46 1957 208 209
18. T. Efferth, A. Olbrich, A. Sauerbrey, D.D. Ross, E. Gebhart, and M. Neugebauer Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug-resistant tumor cells Anticancer Research 22 2002 4221 4224
19. C.C. Faleiro, S.T.H. Elias, L.C. Cavalcanti, and A.S.S. Cavalcanti O extrato das folhas de babosa, Aloe vera na cicatrização de feridas experimentais em pele de ratos, num ensaio controlado por placebo Natureza on Line 7 2009 56 60
20. P.K. Ferreira, M.M. Campos, and J.B. Calixto The role of sensorial neuropeptides in the edematogenic responses mediated by B(1) agonist des-Arg (9) BK in rats pre-treated with LPS Regulatory Peptides 89 2000 29 35
21. S. Hunskaar, and K. Hole The formalin test in mice: dissociation between inflammatory and non-inflammatory pain Pain 30 1987 103 114
22. G.F. Ibironke, and K.I. Ajiboye Studies on the anti-inflammatory and analgesic properties of Chenopodium ambrosioides leaf extract in rats International Journal of Pharmacology 3 2007 111 115
23. P. Kalil-Gaspar Neuropeptídeos na pele Anais Brasileiros de Dermatologia 78 2003 483 498
24. G. Kaur, H. Hamid, A. Ali, M.S. Alam, and M. Athar Antiinflammatory evaluation of alcoholic extract of galls of Quercus infectoria Journal of Ethnopharmacology 90 2004 285 292
25. D.G. Kinsgton Modern natural products drug discovery and its relevance to biodiversity conservation Journal of Natural Products 74 2011 456 511
26. M.M. Kliks Studies on the traditional herbal anthelmintic Chenopodium ambrosioides L.: ethonopharmacological evalution and clinical fields trials Social Science and Medicine 21 1985 879 886
27. Z. Kokanova-Nedialkova, P.T. Nedialkov, and S.D. Nikolov The genus Chenopodium: phytochemistry, ethnopharmacology and pharmacology Pharmacognosy Review 3 2009 280 306
28. R. Kumar, A.K. Mishra, N.K. Dubey, and Y.B. Tripathi Evaluation of Chenopodium ambrosioides oil as a potential source of antifungal, antiaflatoxigenic and antioxidant activity International Journal of Food Microbiology 115 2007 159 164
29. H. Lorenzi, and F.J.A. Matos Plantas medicinais no Brasil: nativas e exóticas cultivadas 2002 Instituto Plantarum de Estudos da Flora Nova Odessa - SP
30. N.Lp. Martins, O. Malafaia, J.M. Ribas-Filho, M. Heibel, R.N. Baldez, P.R.L. Vasconcelos, H. Moreira, M. Mazza, P.A.N. Nassif, and T.Z. Wallbach Análise comparativa da cicatrização da pele com o uso intraperitoneal de extrato aquoso de Orbignya phalerata (babaçu). Estudo controlado em ratos Acta Cirúrgica Brasileira 21 2006 66 75
31. W.M. Mattos, J. Ferreira, G.P. Richetti, R. Niero, R.A. Yunes, and J.B. Calixto Antinociceptive properties produced by the pregnane compound velutinol A isolated from Mandevilla velutina Neuropeptides 40 2006 125 132
32. M.A. Montoya-Cabrera, P. Escalante-Galindo, M. Meckes-Fisher, G. Sánchez-Vaca, E. Flores-Alvarez, and M. Reynoso-García Fatal poisoning caused by oil of epazote, Chenopodium graveolens Gaceta Médicado Mexico 132 1996 433 437
33. A.R. Moore Pleural models of inflammation: immune and nonimmune Methods in Molecular Biology 225 2003 123 128
34. F.R. Nonato, T.M.O. Nogueira, T.A.A. Barros, A.M. Lucchese, C.E.C. Oliveira, R.R.S. Santos, M.B.P. Soares, and C.F. Villarreal Antinociceptive and anti-inflammatory activities of Adiantum latifolium Lam.: evidence for a role of IL-1 inhibition Journal of Ethnopharmacology 136 2011 518 524
35. O.A. Olajide, S.O. Awe, and J.K. Makinde Pharmacological screening of the methanolic extract of Chenopodium ambrosioides Fitoterapia 68 1997 529 532
36. A. Panthong, D. Kanjanapothi, T. Taesotikul, A. Phankummoon, K. Panthong, and V. Reutrakul Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre Journal of Ethnopharmacology 91 2004 237 242
37. W.S. Pereira, B.P. Ribeiro, A.I.P. Sousa, I.C.P.B. Serra, N.S. Mattar, T.S. Fortes, A.S. Reis, L.A. Silva, E.S.B. Barroqueiro, R.N.M. Guerra, and F.R.F. Nascimento Evaluation of the subchronic toxicity of oral treatment with Chenopodium ambrosioides in mice Journal of Ethnopharmacology 127 2010 602 605
38. 2 in mice Journal of Pharmacology and Experimental Therapeutics 296 2001 7 14
39. T.S.F. Saleh, J.B. Calixto, and Y.S. Medeiros Anti-inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy British Journal of Pharmacology 118 1996 811 819
40. T.S. Saleh, J.B. Calixto, and Y.S. Medeiros Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan Peptides 20 1999 949 956
41. A.R. Santos, and J.B. Calixto Ruthenium red and capsazepineantinociceptive effect in formalin and capsaicina models of pain in mice Neuroscience Letters 235 1997 73 76
42. R.A. Saraiva, M.K. Araruna, R.C. Oliveira, K.D. Menezes, G.O. Leite, M.R. Kerntopf, J.G. Costa, J.B. Rocha, A.R. Tomé, A.R. Campos, and I.R. Menezes Topical anti-inflammatory effect of Caryocar coriaceum Wittm. (Caryocaraceae) fruit pulp fixed oil on mice ear oedema induced by different irritant agents Journal of Ethnopharmacology 136 2011 504 510
43. M.R. Sulaiman, A. Padzil, K. Shaari, S. Khalid, W. Shaikmossadeq, A. Shahmohamad, S. Ahmad, A. Akira, D. Israf, and N. Lajis Antinociceptive activity of Melicope ptelefolia ethanolic extract in experimental animals Journal of Biomedicine and Biotechnology 2010 2010 1 6
44. E.S.J. Smith, G.R.C. Blass, G.R. Lewin, and T.J. Park Absence of histamine-induced itch in the African naked mole-rat and rescue by substance P Molecular Pain 6 2010 1 6
45. S. Terraciano, M. Aquino, M. Rodriguez, M.C. Monti, A. Casapullo, R. Riccio, and L. Gomez-Paloma Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-kappaB and other unidentified targets Current Medicinal Chemistry 13 2006 1947 1969
46. J.C. Zanini, Y.S. Medeiros, A.B. Cruz, R.A. Yunes, and J.B. Calixto Actions of compounds from Mandevilla velutina on croton oil-induced ear oedema in mice. A comparative study with steroidal and nonsteroidal anti-inflammatory drugs Phytotherapy Research 6 1992 1 5
47. M. Zimmermann Ethical guidelines for investigations of experimental pain in conscious animals Pain 16 1983 109 110