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Volumn 19, Issue 33, 2012, Pages 5658-5663

Toxicokinetics of cocaine and metabolites: The forensic toxicological approach

Author keywords

Blood; Cocaine; Cocaine metabolites; Fetus fluids; Fetus tissues; Hair; Oral fluid; Review; Sweat; Toxicokinetics; Urine

Indexed keywords

ANHYDROECGONINE ETHYL ESTER; ANHYDROECGONINE METHYL ESTER; BENZOYLECGONINE; COCAINE; DRUG METABOLITE; ECGONINE; ECGONINE METHYL ESTER; HOMOCOCAINE; HYDROXYBENZOYLECGONINE; NORCOCAINE; UNCLASSIFIED DRUG;

EID: 84871268341     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712803988794     Document Type: Article
Times cited : (19)

References (65)
  • 2
    • 0004638706 scopus 로고    scopus 로고
    • Karch S. B, Ed., CRC press, Boca Raton
    • Jenkins, A. J. and Cone E. J. in Drug Abuse Handbook, Karch S. B, Ed., CRC press, Boca Raton, 1998, pp. 184-187
    • (1998) Drug Abuse Handbook. , pp. 184-187
    • Jenkins, A.J.1    Cone, E.J.2
  • 4
    • 0029145959 scopus 로고
    • Pharmacokinetics and pharmacodynamics of cocaine
    • Cone, E. J. Pharmacokinetics and pharmacodynamics of cocaine. J Anal Toxicol., 1995, 19, 459-478.
    • (1995) J Anal Toxicol. , vol.19 , pp. 459-478
    • Cone, E.J.1
  • 6
    • 2342515543 scopus 로고    scopus 로고
    • Sublingual Cocaine. Novel recurrence of an ancient practice
    • Clapp, L.; Martin, B.; Beresford, T. P. Sublingual Cocaine. Novel recurrence of an ancient practice. Clin Neuropharmacol., 2004, 27, 93-94.
    • (2004) Clin Neuropharmacol. , vol.27 , pp. 93-94
    • Clapp, L.1    Martin, B.2    Beresford, T.P.3
  • 7
    • 0035142989 scopus 로고    scopus 로고
    • Contribution of the active metabolite, norcocaine, to cocaine's effects after intravenous and oral administration in rats: Pharmacodynamics
    • Wang, Q.; Simpao, A.; Sun, L.; Falk, J. L.; Lau, C. E. Contribution of the active metabolite, norcocaine, to cocaine's effects after intravenous and oral administration in rats: pharmacodynamics. Psychopharmacology, 2001, 153:341-52.
    • (2001) Psychopharmacology , vol.153 , pp. 341-352
    • Wang, Q.1    Simpao, A.2    Sun, L.3    Falk, J.L.4    Lau, C.E.5
  • 8
    • 0242551164 scopus 로고    scopus 로고
    • The pharmacology of cocaethylene in humans following cocaine and ethanol administration
    • Harris, D. S.; Everhart, E. T.; Mendelson. J.; Jones R. T. The pharmacology of cocaethylene in humans following cocaine and ethanol administration. Drug Alcohol Depend., 2003, 72:169-182.
    • (2003) Drug Alcohol Depend. , vol.72 , pp. 169-182
    • Harris, D.S.1    Everhart, E.T.2    Mendelson, J.3    Jones, R.T.4
  • 11
    • 0037027836 scopus 로고    scopus 로고
    • Chromatographic methods for the determination of markers of chronic and acute alcohol consumption
    • Musshoff, F. Chromatographic methods for the determination of markers of chronic and acute alcohol consumption. J. Chromatogr. B, 2002, 781:457-480.
    • (2002) J. Chromatogr. B , vol.781 , pp. 457-480
    • Musshoff, F.1
  • 12
    • 34547659359 scopus 로고    scopus 로고
    • Markers of chronic alcohol use in hair: Comparison of ethyl glucuronide and cocaethylene in cocaine users
    • Politi, L.; Zucchella, A.; Morini, L.; Stramesi, C.; Polettini, A. Markers of chronic alcohol use in hair: comparison of ethyl glucuronide and cocaethylene in cocaine users. Forensic Sci Int., 2007, 172:23-27.
    • (2007) Forensic Sci Int. , vol.172 , pp. 23-27
    • Politi, L.1    Zucchella, A.2    Morini, L.3    Stramesi, C.4    Polettini, A.5
  • 15
    • 0028225826 scopus 로고
    • Simultaneous measurement of cocaine, cocaethylene, their metabolites, and "crack" pyrolysis products by gas chromatography-mass spectrometry
    • Cone, E. J.; Hillsgrove, M.; Darwin, W. D. Simultaneous measurement of cocaine, cocaethylene, their metabolites, and "crack" pyrolysis products by gas chromatography-mass spectrometry. Clin Chem., 1994, 40:1299-3051
    • (1994) Clin Chem. , vol.40 , pp. 1299-3051
    • Cone, E.J.1    Hillsgrove, M.2    Darwin, W.D.3
  • 16
    • 0031054391 scopus 로고    scopus 로고
    • Evidence of crack use by anhydroecgonine methylester identification
    • Kintz, P.; Sengler, C.; Cirimele, V.; Mangin, P. Evidence of crack use by anhydroecgonine methylester identification. Hum Exp Toxicol., 1997, 16:123-127.
    • (1997) Hum Exp Toxicol. , vol.16 , pp. 123-127
    • Kintz, P.1    Sengler, C.2    Cirimele, V.3    Mangin, P.4
  • 17
    • 29144446172 scopus 로고    scopus 로고
    • Detection of smoked cocaine marker (anhydroecgonine methylester) in nails
    • Ragoucy-Sengler, C.; Kintz, P. Detection of smoked cocaine marker (anhydroecgonine methylester) in nails. J Anal Toxicol., 2005, 29:765-768.
    • (2005) J Anal Toxicol. , vol.29 , pp. 765-768
    • Ragoucy-Sengler, C.1    Kintz, P.2
  • 18
    • 27844537839 scopus 로고    scopus 로고
    • Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim
    • Myers, A. L.; Williams, H. E.; Kraner, J. C.; Callery, P. S. Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim. J Forensic Sci., 2005, 50:1481-1485.
    • (2005) J Forensic Sci. , vol.50 , pp. 1481-1485
    • Myers, A.L.1    Williams, H.E.2    Kraner, J.C.3    Callery, P.S.4
  • 20
    • 77749311613 scopus 로고    scopus 로고
    • Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine
    • Smith, M. L.; Shimomura, E.; Paul, B. D.; Cone, E. J.; Darwin, W. D.; Huestis, M. A. Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine. J Anal Toxicol., 2010, 34:57-63.
    • (2010) J Anal Toxicol. , vol.34 , pp. 57-63
    • Smith, M.L.1    Shimomura, E.2    Paul, B.D.3    Cone, E.J.4    Darwin, W.D.5    Huestis, M.A.6
  • 21
    • 0141682620 scopus 로고    scopus 로고
    • Urine testing for cocaine abuse: Metabolic and excretion patterns following different routes of administration and methods for detection of falsenegative results
    • Cone E. J.; Sampson-Cone A. H.; Darwin, W. D.; Huestis, M. A.; Oyler, J. M. Urine testing for cocaine abuse: metabolic and excretion patterns following different routes of administration and methods for detection of falsenegative results. J Anal Toxicol., 2003, 27:386-401.
    • (2003) J Anal Toxicol. , vol.27 , pp. 386-401
    • Cone, E.J.1    Sampson-Cone, A.H.2    Darwin, W.D.3    Huestis, M.A.4    Oyler, J.M.5
  • 22
    • 24144491033 scopus 로고    scopus 로고
    • Oral fluid testing for driving under the influence of drugs: History, recent progress and remaining challenges
    • Verstraete, A. G. Oral fluid testing for driving under the influence of drugs: history, recent progress and remaining challenges. Forensic Sci Int., 2005, 150:143-50.
    • (2005) Forensic Sci Int. , vol.150 , pp. 143-150
    • Verstraete, A.G.1
  • 23
    • 79956210911 scopus 로고    scopus 로고
    • European Workplace Drug Testing Society. Guidelines for European workplace drug testing in oral fluid
    • Cooper, G.; Moore, C.; George, C.; Pichini, S. European Workplace Drug Testing Society. Guidelines for European workplace drug testing in oral fluid. Drug Test Anal., 2011, 3:269-276.
    • (2011) Drug Test Anal. , vol.3 , pp. 269-276
    • Cooper, G.1    Moore, C.2    George, C.3    Pichini, S.4
  • 24
    • 34447638724 scopus 로고    scopus 로고
    • Drug testing in oral fluid
    • Drummer O. H. Drug testing in oral fluid. Clin Biochem Rev. 2006 27:147-59.
    • (2006) Clin Biochem Rev. , vol.27 , pp. 147-159
    • Drummer, O.H.1
  • 25
    • 70449701839 scopus 로고    scopus 로고
    • Oral fluid testing for drugs of abuse
    • Bosker, W. M.; Huestis, M. A. Oral fluid testing for drugs of abuse. Clin Chem. 2009 55:1910-1931.
    • (2009) Clin Chem. , vol.55 , pp. 1910-1931
    • Bosker, W.M.1    Huestis, M.A.2
  • 26
    • 84864367864 scopus 로고    scopus 로고
    • Evaluation of four oral fluid devices (DDS (®), Drugtest 5000 (®), Drugwipe 5+ (®) and RapidSTAT (®)) for on-site monitoring drugged driving in comparison with UHPLC-MS/MS analysis
    • May 1. in press
    • Strano-Rossi, S.; Castrignanò, E.; Anzillotti, L.; Serpelloni, G.; Mollica, R.; Tagliaro, F.; Pascali, J. P.; di Stefano, D.; Sgalla, R.; Chiarotti, M. Evaluation of four oral fluid devices (DDS (®), Drugtest 5000 (®), Drugwipe 5+ (®) and RapidSTAT (®)) for on-site monitoring drugged driving in comparison with UHPLC-MS/MS analysis. Forensic Sci Int. 2012 May 1. [in press]
    • (2012) Forensic Sci Int.
    • Strano-Rossi, S.1    Castrignanò, E.2    Anzillotti, L.3    Serpelloni, G.4    Mollica, R.5    Tagliaro, F.6    Pascali, J.P.7    Di Stefano, D.8    Sgalla, R.9    Chiarotti, M.10
  • 29
    • 24144451122 scopus 로고    scopus 로고
    • Review: Pharmacokinetics of illicit drugs in oral fluid
    • Drummer, O. H. Review: Pharmacokinetics of illicit drugs in oral fluid. Forensic Sci Int., 2005, 150:133-421
    • (2005) Forensic Sci Int. , vol.150 , pp. 133-421
    • Drummer, O.H.1
  • 30
    • 36448978515 scopus 로고    scopus 로고
    • Prevalence and disposition of drugs of abuse and opioid treatment drugs in oral fluid
    • Cone, E. J.; Clarke, J.; Tsanaclis, L. Prevalence and disposition of drugs of abuse and opioid treatment drugs in oral fluid. J Anal Toxicol., 2007, 31:424-433.
    • (2007) J Anal Toxicol. , vol.31 , pp. 424-433
    • Cone, E.J.1    Clarke, J.2    Tsanaclis, L.3
  • 31
    • 4644271920 scopus 로고    scopus 로고
    • Detection times of drugs of abuse in blood, urine, and oral fluid
    • Verstraete, A. G. Detection times of drugs of abuse in blood, urine, and oral fluid. Ther Drug Monit., 2004, 26:200-205.
    • (2004) Ther Drug Monit. , vol.26 , pp. 200-205
    • Verstraete, A.G.1
  • 32
    • 33748557224 scopus 로고    scopus 로고
    • Sampson-Cone A. Effect of repeated cocaine administration on detection times in oral fluid and urine
    • Jufer R.; Walsh S. L.; Cone, E. J., Sampson-Cone A. Effect of repeated cocaine administration on detection times in oral fluid and urine. J Anal Toxicol., 2006, 30:458-462.
    • (2006) J Anal Toxicol. , vol.30 , pp. 458-462
    • Jufer, R.1    Walsh, S.L.2    Cone, E.J.3
  • 33
    • 77957266877 scopus 로고    scopus 로고
    • Pharmacokinetics of cocaine and metabolites in human oral fluid and correlation with plasma concentrations after controlled administration
    • Scheidweiler, K. B.; Spargo, E. A.; Kelly, T. L.; Cone, E. J.; Barnes, A. J.; Huestis, M. A. Pharmacokinetics of cocaine and metabolites in human oral fluid and correlation with plasma concentrations after controlled administration. Ther Drug Monit., 2010, 32:628-637.
    • (2010) Ther Drug Monit. , vol.32 , pp. 628-637
    • Scheidweiler, K.B.1    Spargo, E.A.2    Kelly, T.L.3    Cone, E.J.4    Barnes, A.J.5    Huestis, M.A.6
  • 34
    • 0030880651 scopus 로고    scopus 로고
    • Cocaine disposition in saliva following intravenous, intranasal, and smoked administration
    • Cone, E. J.; Oyler, J.; Darwin, W. D. Cocaine disposition in saliva following intravenous, intranasal, and smoked administration. J Anal Toxicol., 1997, 21:465-75.
    • (1997) J Anal Toxicol. , vol.21 , pp. 465-475
    • Cone, E.J.1    Oyler, J.2    Darwin, W.D.3
  • 35
    • 20544444189 scopus 로고    scopus 로고
    • Driving under the influence of drugs - Evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptoms
    • Toennes, S. W.; Kauert, G. F.; Steinmeyer, S.; Moeller, M. R. Driving under the influence of drugs - evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptoms. Forensic Sci Int., 2005, 152:149-155.
    • (2005) Forensic Sci Int. , vol.152 , pp. 149-155
    • Toennes, S.W.1    Kauert, G.F.2    Steinmeyer, S.3    Moeller, M.R.4
  • 37
    • 84860247084 scopus 로고    scopus 로고
    • Value of the concept of minimal detectable dosage in human hair
    • Kintz P. Value of the concept of minimal detectable dosage in human hair. Forensic Sci Int., 2012, 218:28-30.
    • (2012) Forensic Sci Int. , vol.218 , pp. 28-30
    • Kintz, P.1
  • 38
    • 0028936335 scopus 로고
    • Testing human hair for drugs of abuse. IV. Environmental cocaine contamination and washing effects
    • Wang, W. L.; Cone, E. J. Testing human hair for drugs of abuse. IV. Environmental cocaine contamination and washing effects. Forensic Sci Int., 1995, 70:39-51.
    • (1995) Forensic Sci Int. , vol.70 , pp. 39-51
    • Wang, W.L.1    Cone, E.J.2
  • 39
    • 4744340238 scopus 로고    scopus 로고
    • Notice of proposed revisions to the mandatory guidelines for federal workplace drug testing programs
    • SAHMSA Substance Abuse and Mental Health Services Administration
    • SAHMSA (Substance Abuse and Mental Health Services Administration). Notice of proposed revisions to the mandatory guidelines for federal workplace drug testing programs. Fed. Regist., 2004, 69:19673-19732.
    • (2004) Fed. Regist. , vol.69 , pp. 19673-19732
  • 40
    • 33750184118 scopus 로고    scopus 로고
    • External contamination of hair with cocaine: Evaluation of external cocaine contamination and development of performance-testing materials
    • Stout, P. R.; Ropero-Miller, J. D.; Baylor, M. R.; Mitchell J. M. External contamination of hair with cocaine: evaluation of external cocaine contamination and development of performance-testing materials. J Anal Toxicol. 2006 30:490-500.
    • (2006) J Anal Toxicol. , vol.30 , pp. 490-500
    • Stout, P.R.1    Ropero-Miller, J.D.2    Baylor, M.R.3    Mitchell, J.M.4
  • 41
    • 84866778839 scopus 로고    scopus 로고
    • Cocaine Analytes in Human Hair: Evaluation of Concentration Ratios in Different Cocaine Sources, Drug-User Populations and Surface-Contaminated Specimens
    • Ropero-Miller J. D.; Huestis M. A.; Stout, PR. Cocaine Analytes in Human Hair: Evaluation of Concentration Ratios in Different Cocaine Sources, Drug-User Populations and Surface-Contaminated Specimens. J Anal Toxicol. 2012, 36:390-398.
    • (2012) J Anal Toxicol. , vol.36 , pp. 390-398
    • Ropero-Miller, J.D.1    Huestis, M.A.2    Stout, P.R.3
  • 42
    • 78049491781 scopus 로고    scopus 로고
    • Hair analysis for cocaine continues to be a valuable tool in forensic and clinical toxicology
    • Pragst, F.; Sachs, H.; Kintz, P. Hair analysis for cocaine continues to be a valuable tool in forensic and clinical toxicology. J Anal Toxicol., 2010, 34:354-355
    • (2010) J Anal Toxicol. , vol.34 , pp. 354-355
    • Pragst, F.1    Sachs, H.2    Kintz, P.3
  • 43
    • 68849120844 scopus 로고    scopus 로고
    • Considerations on the utility of hair analysis for cocaine
    • Le Beau, M. A.; Montgomery M. A. Considerations on the utility of hair analysis for cocaine. J Anal Toxicol., 2009, 33:343-344.
    • (2009) J Anal Toxicol. , vol.33 , pp. 343-344
    • Le Beau, M.A.1    Montgomery, M.A.2
  • 45
    • 0029100304 scopus 로고
    • Hair analysis for drugs of abuse. X. Effect of physicochemical properties of drugs on the incorporation rates into hair
    • Nakahara, Y.; Takahashi, K.; Kikura, R. Hair analysis for drugs of abuse. X. Effect of physicochemical properties of drugs on the incorporation rates into hair. Biol Pharm Bull., 1995, 18:1223-1227.
    • (1995) Biol Pharm Bull. , vol.18 , pp. 1223-1227
    • Nakahara, Y.1    Takahashi, K.2    Kikura, R.3
  • 46
    • 0026720816 scopus 로고
    • Hair analysis for drugs of abuse. V. The facility in incorporation of cocaine into hair over its major metabolites, benzoylecgonine and ecgonine methyl ester
    • Nakahara, Y.; Ochiai, T.; Kikura, R. Hair analysis for drugs of abuse. V. The facility in incorporation of cocaine into hair over its major metabolites, benzoylecgonine and ecgonine methyl ester. Arch Toxicol. 1992;66:446-449.
    • (1992) Arch Toxicol. , vol.66 , pp. 446-449
    • Nakahara, Y.1    Ochiai, T.2    Kikura, R.3
  • 47
    • 0033670526 scopus 로고    scopus 로고
    • The incorporation of cocaine and metabolites into hair: Effects of dose and hair pigmentation
    • Hubbard, D. L.; Wilkins, D. G.; Rollins, D. E. The incorporation of cocaine and metabolites into hair: effects of dose and hair pigmentation. Drug Metab Dispos., 2000, 28:1464-1469.
    • (2000) Drug Metab Dispos. , vol.28 , pp. 1464-1469
    • Hubbard, D.L.1    Wilkins, D.G.2    Rollins, D.E.3
  • 48
    • 67449084994 scopus 로고    scopus 로고
    • Pharmacokinetics of disappearance of cocaine from hair after discontinuation of drug use
    • Garcia-Bournissen, F.; Moller, M.; Nesterenko, M.; Karaskov, T.; Koren G. Pharmacokinetics of disappearance of cocaine from hair after discontinuation of drug use. Forensic Sci Int., 2009, 189:24-27.
    • (2009) Forensic Sci Int. , vol.189 , pp. 24-27
    • Garcia-Bournissen, F.1    Moller, M.2    Nesterenko, M.3    Karaskov, T.4    Koren, G.5
  • 49
  • 50
    • 0028942149 scopus 로고
    • Measurement of drugs in neonatal hair; a window to fetal exposure
    • Koren, G. Measurement of drugs in neonatal hair; a window to fetal exposure. Forensic Sci Int., 1995, 70:77-82.
    • (1995) Forensic Sci Int. , vol.70 , pp. 77-82
    • Koren, G.1
  • 51
    • 0036146704 scopus 로고    scopus 로고
    • Estimation of fetal exposure to drugs of abuse, environmental tobacco smoke, and ethanol
    • Koren, G.; Chan, D.; Klein, J.; Karaskov, T. Estimation of fetal exposure to drugs of abuse, environmental tobacco smoke, and ethanol. Ther Drug Monit., 2002, 24:23-25.
    • (2002) Ther Drug Monit. , vol.24 , pp. 23-25
    • Koren, G.1    Chan, D.2    Klein, J.3    Karaskov, T.4
  • 53
    • 0034266080 scopus 로고    scopus 로고
    • Dose-response effect of cocaine on newborn head circumference
    • Bateman, D. A.; Chiriboga, C. A. Dose-response effect of cocaine on newborn head circumference. Pediatrics., 2000, 106:E33.
    • (2000) Pediatrics. , vol.106
    • Bateman, D.A.1    Chiriboga, C.A.2
  • 54
    • 0034662201 scopus 로고    scopus 로고
    • Cocaine use during pregnancy and intrauterine growth retardation: New insights based on maternal hair tests
    • Kuhn, L.; Kline, J., Ng, S., Levin, B., Susser, M. Cocaine use during pregnancy and intrauterine growth retardation: new insights based on maternal hair tests. Am J Epidemiol., 2000, 152:112-119.
    • (2000) Am J Epidemiol. , vol.152 , pp. 112-119
    • Kuhn, L.1    Kline, J.2    Ng, S.3    Levin, B.4    Susser, M.5
  • 55
    • 0035296530 scopus 로고    scopus 로고
    • Cocaine: Effects of in utero exposure on the fetus and neonate
    • Askin, D. F.; Diehl-Jones, B. Cocaine: effects of in utero exposure on the fetus and neonate. J Perinat Neonatal Nurs., 2001, 14:83-102.
    • (2001) J Perinat Neonatal Nurs. , vol.14 , pp. 83-102
    • Askin, D.F.1    Diehl-Jones, B.2
  • 56
    • 0031711965 scopus 로고    scopus 로고
    • Diagnosing intrauterine exposure to cocaine by hair testing: Six years of clinical use
    • Koren, G., Klein, J., McMartin, K. Diagnosing intrauterine exposure to cocaine by hair testing: six years of clinical use. Ther Drug Monit., 1998, 20:478-480.
    • (1998) Ther Drug Monit. , vol.20 , pp. 478-480
    • Koren, G.1    Klein, J.2    McMartin, K.3
  • 57
    • 33847145071 scopus 로고    scopus 로고
    • Cocaine detection in maternal and neonatal hair: Implications to fetal toxicology
    • Garcia-Bournissen, F.; Rokach, B.; Karaskov, T.; Koren G. Cocaine detection in maternal and neonatal hair: implications to fetal toxicology. Ther Drug Monit., 2007, 29:71-76.
    • (2007) Ther Drug Monit. , vol.29 , pp. 71-76
    • Garcia-Bournissen, F.1    Rokach, B.2    Karaskov, T.3    Koren, G.4
  • 58
    • 0033663246 scopus 로고    scopus 로고
    • Doserelated differences in the distribution of cocaine in the maternal-fetoplacental compartments in rats
    • Morishima, H. O.; Okutomi, T.; Whittington, R. A.; Cooper, T. B. Doserelated differences in the distribution of cocaine in the maternal-fetoplacental compartments in rats. Neurotoxicol Teratol., 2000 22:837-844.
    • (2000) Neurotoxicol Teratol. , vol.22 , pp. 837-844
    • Morishima, H.O.1    Okutomi, T.2    Whittington, R.A.3    Cooper, T.B.4
  • 59
    • 0035032864 scopus 로고    scopus 로고
    • Pharmacokinetics of cocaine in maternal and fetal rhesus monkeys at midgestation
    • Zhou, M.; Song, Z. M.; Lidow, M. S. Pharmacokinetics of cocaine in maternal and fetal rhesus monkeys at midgestation. J Pharmacol Exp Ther., 2001, 297:556-562.
    • (2001) J Pharmacol Exp Ther. , vol.297 , pp. 556-562
    • Zhou, M.1    Song, Z.M.2    Lidow, M.S.3
  • 60
    • 33644698750 scopus 로고    scopus 로고
    • Drugs of abuse testing in meconium
    • Gareri, J.; Klein, J.; Koren, G. Drugs of abuse testing in meconium. Clin Chim Acta., 2006, 366:101-111.
    • (2006) Clin Chim Acta. , vol.366 , pp. 101-111
    • Gareri, J.1    Klein, J.2    Koren, G.3
  • 62
    • 0029796376 scopus 로고    scopus 로고
    • Cocaine disposition in meconium from newborns of cocaine-abusing mothers and urine of adult drug users
    • Oyler, J.; Darwin, W. D.; Preston, K. L.; Suess, P.; Cone, EJ. Cocaine disposition in meconium from newborns of cocaine-abusing mothers and urine of adult drug users. J Anal Toxicol., 1996 20:453-462.
    • (1996) J Anal Toxicol. , vol.20 , pp. 453-462
    • Oyler, J.1    Darwin, W.D.2    Preston, K.L.3    Suess, P.4    Cone, E.J.5
  • 64
    • 0002804526 scopus 로고    scopus 로고
    • Karch S. B, Ed., CRC press, Boca Raton
    • Huestis, M. A.; Cone, E. J. in Drug Abuse Handbook, Karch S. B, Ed., CRC press, Boca Raton, 1998, pp. 799-857.
    • (1998) Drug Abuse Handbook. , pp. 799-857
    • Huestis, M.A.1    Cone, E.J.2
  • 65
    • 27444431709 scopus 로고    scopus 로고
    • Disposition of cocaine and its metabolites in human sweat after controlled cocaine administration
    • Kacinko, S. L.; Barnes, A. J.; Schwilke, E. W.; Cone, E. J.; Moolchan, E. T.; Huestis, M. A.. Disposition of cocaine and its metabolites in human sweat after controlled cocaine administration. Clin Chem., 2005 51:2085-2094.
    • (2005) Clin Chem. , vol.51 , pp. 2085-2094
    • Kacinko, S.L.1    Barnes, A.J.2    Schwilke, E.W.3    Cone, E.J.4    Moolchan, E.T.5    Huestis, M.A.6


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