Disposition of cocaine and its metabolites in human sweat after controlled cocaine administration

Clinical Chemistry

Volumn 51, Issue 11, 2005, Pages 2085-2094

  Kacinko, Sherri L ^a   Barnes, Allan J ^a   Schwilke, Eugene W ^a   Cone, Edward J ^b   Moolchan, Eric T ^a   Huestis, Marilyn A ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBENZOYLECGONINE; 3 HYDROXYCOCAINE; 4 HYDROXYBENZOYLECGONINE; 4 HYDROXYCOCAINE; BENZOYLECGONINE; COCAINE; COCAINE DERIVATIVE; DRUG METABOLITE; ECGONINE; ECGONINE ETHYL ESTER; ECGONINE METHYL ESTER; HOMOCOCAINE; NORCOCAETHYLENE; NORCOCAINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CRIMINAL JUSTICE; DRUG DISPOSITION; DRUG EXPOSURE; DRUG MONITORING; EMPLOYMENT; EVALUATION; EXCRETION; FEMALE; GAS CHROMATOGRAPHY; HUMAN; MALE; MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; RELIABILITY; SWEAT; TECHNIQUE;

ADULT; COCAINE; FEMALE; HUMANS; MALE; SUBSTANCE ABUSE DETECTION; SWEAT;

EID: 27444431709     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2005.054338     Document Type: Article

References (16)

1. US Department of Health and Human Services. Proposed revisions to mandatory guidelines for federal workplace drug testing programs. Fed Regist 2004;69:19673-732.
2. Skopp G, Putsch L. Perspiration versus saliva-basic aspects concerning their use in roadside drug testing. Int J Legal Med 1999;112:213-21.
3. Huestis MA, Cone EJ. Alternative testing matrices. In: Karch SB, ed. Drug abuse handbook. Boca Raton, FL: CRC Press, 1998:799-857.
4. Kidwell DA, Holland JC, Athanaselis S. Testing for drugs of abuse in saliva and sweat. J Chromatogr 1998;713:111-35.
5. Stimmel B, Kreek MJ. Neurobiology of addictive behaviors and its relationship to methadone maintenance. Mt Sinai J Med 2000;67:375-80.
6. Kidwell DA, Smith FP. Susceptibility of Pharmchek drugs of abuse patch to environmental contamination. Forensic Sci Int 2001;116:89-106.
7. Winhusen TM, Somoza EC, Singal B, Kim S, Horn PS, Rotrosen J. Measuring outcome in cocaine clinical trials: a comparison of sweat patches with urine toxicology and participant self-report. Addiction 2003;98:117-324.
8. Uemura N, Nath RP, Harkey MR, Henderson GL, Mendelson J, Jones RT. Cocaine levels in sweat collection patches vary by location of patch placement and decline over time. J Anal Toxicol 2004;28:253-9.
9. Saito T, Wtsadik A, Scheidweiler KB, Fortne N, Takeichi S, Huestis MA. Validated gas chromatographic-negative ion chemical ionization mass spectrometric method for δ(9)-tetrahydrocannabinol in sweat patches. Clin Chem 2004;50:2083-90.
10. US Department of Justice. Federal cocaine offenses: an analysis of crack and powder penalties. Washington, DC: US Department of Justice, 2002:42pp.
11. Huestis MA, Oyler JM, Cone EJ, Wstadik AT, Schoendorfer D, Joseph RE Jr. Sweat testing for cocaine, codeine and metabolites by gas chromatography-mass spectrometry. J Chromatogr 1999;733:247-64.
12. Cone EJ, Hillsgrove MJ, Jenkins AJ, Keenan RM, Darwin WD. Sweat testing for heroin, cocaine, and metabolites. J Anal Toxicol 1994;18:298-305.
13. Preston KL, Huestis MA, Wong CJ, Umbricht A, Goldberger BA, Cone EJ. Monitoring cocaine use in substance abuse treatment patients by sweat and urine testing. J Anal Toxicol 1999;23:313-22.
14. Moody DE, Spanbauer AC, Taccogno JL, Smith EK. Comparative analysis of sweat patches for cocaine (and metabolites) by radioimmunoassay and gas chromatography-positive ion chemical ionization-mass spectrometry. J Anal Toxicol 2004;28:86-93.
15. Liberty HJ, Johnson BD, Fortner N. Detecting cocaine use through sweat testing: multilevel modeling of sweat patch length-of-wear data. J Anal Toxicol 2004;28:667-73.
16. Burns M, Baselt RC. Monitoring drug use with a sweat patch: an experiment with cocaine. J Anal Toxicol 1995;19:41-8.