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Volumn 105, Issue 3, 2012, Pages 337-340

Conducting radiogenomic research - Do not forget careful consideration of the clinical data

Author keywords

Normal tissue radiosensitivity; Predictive markers; Single nucleotide polymorphisms

Indexed keywords

ARTICLE; BLADDER CANCER; BLADDER DISEASE; BREAST CANCER; CANCER RADIOTHERAPY; DIARRHEA; DOSIMETRY; DYSPHAGIA; DYSPNEA; ERECTILE DYSFUNCTION; GENETIC ASSOCIATION; GENOMICS; GENOTYPE; GYNECOLOGIC CANCER; HEAD AND NECK CANCER; HIGH THROUGHPUT SEQUENCING; HUMAN; MEDICAL RESEARCH; MUCOSA INFLAMMATION; NEOPLASM; PHENOTYPE; PRIORITY JOURNAL; PROCTITIS; PROSTATE CANCER; QUALITY OF LIFE; RADIATION INJURY; RADIOGENOMIC; RADIOLOGY; RECTUM HEMORRHAGE; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN FIBROSIS; TELANGIECTASIA;

EID: 84871191017     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2012.11.004     Document Type: Article
Times cited : (28)

References (27)
  • 1
    • 84871253909 scopus 로고    scopus 로고
    • Will SNPs be useful predictors of normal tissue radiosensitivity in the future?
    • C.N. Andreassen, E. Dikomey, M. Parliament, and C.M. West Will SNPs be useful predictors of normal tissue radiosensitivity in the future? Radiother Oncol 105 2012 283 288
    • (2012) Radiother Oncol , vol.105 , pp. 283-288
    • Andreassen, C.N.1    Dikomey, E.2    Parliament, M.3    West, C.M.4
  • 2
    • 84871202486 scopus 로고    scopus 로고
    • Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients
    • L. Fachal, A. Gomez-Caamano, and P. Peleteiro Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients Radiother Oncol 105 2012 321 328
    • (2012) Radiother Oncol , vol.105 , pp. 321-328
    • Fachal, L.1    Gomez-Caamano, A.2    Peleteiro, P.3
  • 3
    • 58949092475 scopus 로고    scopus 로고
    • Normal tissue reactions to radiotherapy: Towards tailoring treatment dose by genotype
    • G.C. Barnett, C.M. West, and A.M. Dunning Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype Nat Rev Cancer 9 2009 134 142
    • (2009) Nat Rev Cancer , vol.9 , pp. 134-142
    • Barnett, G.C.1    West, C.M.2    Dunning, A.M.3
  • 4
    • 77957864864 scopus 로고    scopus 로고
    • Searching for genetic determinants of normal tissue radiosensitivity - Are we on the right track?
    • C.N. Andreassen Searching for genetic determinants of normal tissue radiosensitivity - are we on the right track? Radiother Oncol 97 2010 1 8
    • (2010) Radiother Oncol , vol.97 , pp. 1-8
    • Andreassen, C.N.1
  • 5
    • 84855321526 scopus 로고    scopus 로고
    • Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: A prospective analysis study
    • G.C. Barnett, C.E. Coles, and R.M. Elliott Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study Lancet Oncol 13 2012 65 77
    • (2012) Lancet Oncol , vol.13 , pp. 65-77
    • Barnett, G.C.1    Coles, C.E.2    Elliott, R.M.3
  • 6
    • 84864868856 scopus 로고    scopus 로고
    • A replicated association between polymorphisms near TNF-alpha and risk for adverse reactions to radiotherapy
    • C.J. Talbot, G.A. Tanteles, and G.C. Barnett A replicated association between polymorphisms near TNF-alpha and risk for adverse reactions to radiotherapy Br J Cancer 107 2012 748 753
    • (2012) Br J Cancer , vol.107 , pp. 748-753
    • Talbot, C.J.1    Tanteles, G.A.2    Barnett, G.C.3
  • 7
    • 77957872526 scopus 로고    scopus 로고
    • No association between SNPs regulating TGF-beta1 secretion and late radiotherapy toxicity to the breast: Results from the RAPPER study
    • G.C. Barnett, C.E. Coles, and N.G. Burnet No association between SNPs regulating TGF-beta1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study Radiother Oncol 97 2010 9 14
    • (2010) Radiother Oncol , vol.97 , pp. 9-14
    • Barnett, G.C.1    Coles, C.E.2    Burnet, N.G.3
  • 9
    • 77957863710 scopus 로고    scopus 로고
    • First report on the patient database for the identification of the genetic pathways involved in patients over-reacting to radiotherapy: GENEPI-II
    • D. De Ruysscher, D. Severin, and E. Barnes First report on the patient database for the identification of the genetic pathways involved in patients over-reacting to radiotherapy: GENEPI-II Radiother Oncol 97 2010 36 39
    • (2010) Radiother Oncol , vol.97 , pp. 36-39
    • De Ruysscher, D.1    Severin, D.2    Barnes, E.3
  • 10
    • 74549176997 scopus 로고    scopus 로고
    • Establishment of a radiogenomics consortium
    • C. West, and B.S. Rosenstein Establishment of a radiogenomics consortium Radiother Oncol 94 2010 117 118
    • (2010) Radiother Oncol , vol.94 , pp. 117-118
    • West, C.1    Rosenstein, B.S.2
  • 11
    • 84871182048 scopus 로고    scopus 로고
    • Individual patient data meta-analysis shows no association between a SNP regulating TGF-beta 1 secretion and late radiotherapy toxicity
    • G.C. Barnett, R.M. Elliott, and J. Alsner Individual patient data meta-analysis shows no association between a SNP regulating TGF-beta 1 secretion and late radiotherapy toxicity Radiother Oncol 105 2012 289 295
    • (2012) Radiother Oncol , vol.105 , pp. 289-295
    • Barnett, G.C.1    Elliott, R.M.2    Alsner, J.3
  • 12
    • 78549233654 scopus 로고    scopus 로고
    • Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer
    • S.L. Kerns, H. Ostrer, and R. Stock Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer Int J Radiat Oncol Biol Phys 78 2010 1292 1300
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 1292-1300
    • Kerns, S.L.1    Ostrer, H.2    Stock, R.3
  • 13
    • 84857565239 scopus 로고    scopus 로고
    • Genome-wide association studies and prediction of normal tissue toxicity
    • C.M. West, A.M. Dunning, and B.S. Rosenstein Genome-wide association studies and prediction of normal tissue toxicity Semin Radiat Oncol 22 2012 91 99
    • (2012) Semin Radiat Oncol , vol.22 , pp. 91-99
    • West, C.M.1    Dunning, A.M.2    Rosenstein, B.S.3
  • 14
    • 80655123141 scopus 로고    scopus 로고
    • Frontiers in molecular radiation biology/oncology
    • H.P. Rodemann, and B.G. Wouters Frontiers in molecular radiation biology/oncology Radiother Oncol 101 2011 1 6
    • (2011) Radiother Oncol , vol.101 , pp. 1-6
    • Rodemann, H.P.1    Wouters, B.G.2
  • 15
    • 0024316738 scopus 로고
    • Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study
    • S.M. Bentzen, H.D. Thames, and M. Overgaard Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study Radiother Oncol 15 1989 267 274 (Pubitemid 19193919)
    • (1989) Radiotherapy and Oncology , vol.15 , Issue.3 , pp. 267-274
    • Bentzen, S.M.1    Thames, H.D.2    Overgaard, M.3
  • 16
    • 84856395883 scopus 로고    scopus 로고
    • Standardized Total Average Toxicity score: A scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies
    • G.C. Barnett, C.M. West, and C.E. Coles Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies Int J Radiat Oncol Biol Phys 82 2012 1065 1074
    • (2012) Int J Radiat Oncol Biol Phys , vol.82 , pp. 1065-1074
    • Barnett, G.C.1    West, C.M.2    Coles, C.E.3
  • 17
    • 76449112804 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: The importance of dose-volume effects
    • S.M. Bentzen, M. Parliament, and J.O. Deasy Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects Int J Radiat Oncol Biol Phys 76 2010 S145 S150
    • (2010) Int J Radiat Oncol Biol Phys , vol.76
    • Bentzen, S.M.1    Parliament, M.2    Deasy, J.O.3
  • 18
    • 28844492570 scopus 로고    scopus 로고
    • Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles?
    • DOI 10.1080/02841860500374513
    • C.N. Andreassen Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles? Acta Oncol 44 2005 801 815 (Pubitemid 41780105)
    • (2005) Acta Oncologica , vol.44 , Issue.8 , pp. 801-815
    • Andreassen, C.N.1
  • 19
    • 0026065036 scopus 로고
    • Relationship between early and late normal-tissue injury after postmastectomy radiotherapy
    • S.M. Bentzen, and M. Overgaard Relationship between early and late normal-tissue injury after postmastectomy radiotherapy Radiother Oncol 20 1991 159 165
    • (1991) Radiother Oncol , vol.20 , pp. 159-165
    • Bentzen, S.M.1    Overgaard, M.2
  • 20
    • 0027267258 scopus 로고
    • Clinical correlations between late normal tissue endpoints after radiotherapy: Implications for predictive assays of radiosensitivity
    • S.M. Bentzen, M. Overgaard, and J. Overgaard Clinical correlations between late normal tissue endpoints after radiotherapy: implications for predictive assays of radiosensitivity Eur J Cancer 29A 1993 1373 1376 (Pubitemid 23195374)
    • (1993) European Journal of Cancer Part A: General Topics , vol.29 , Issue.10 , pp. 1373-1376
    • Bentzen, S.M.1    Overgaard, M.2    Overgaard, J.3
  • 21
    • 80055112674 scopus 로고    scopus 로고
    • The Cambridge Breast Intensity-modulated Radiotherapy Trial: Patient- and treatment-related factors that influence late toxicity
    • G.C. Barnett, J.S. Wilkinson, and A.M. Moody The Cambridge Breast Intensity-modulated Radiotherapy Trial: patient- and treatment-related factors that influence late toxicity Clin Oncol (R Coll Radiol) 23 2011 662 673
    • (2011) Clin Oncol (R Coll Radiol) , vol.23 , pp. 662-673
    • Barnett, G.C.1    Wilkinson, J.S.2    Moody, A.M.3
  • 22
    • 0036669735 scopus 로고    scopus 로고
    • Does variability in normal tissue reactions after radiotherapy have a genetic basis - Where and how to look for it?
    • DOI 10.1016/S0167-8140(02)00154-8, PII S0167814002001548
    • C.N. Andreassen, J. Alsner, and J. Overgaard Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look for it? Radiother Oncol 64 2002 131 140 (Pubitemid 35247890)
    • (2002) Radiotherapy and Oncology , vol.64 , Issue.2 , pp. 131-140
    • Andreassen, C.N.1    Alsner, J.2    Overgaard, J.3
  • 23
    • 33747826874 scopus 로고    scopus 로고
    • Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology
    • DOI 10.1038/nrc1950, PII NRC1950
    • S.M. Bentzen Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology Nat Rev Cancer 6 2006 702 713 (Pubitemid 44286002)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 702-713
    • Bentzen, S.M.1
  • 24
    • 76449086720 scopus 로고    scopus 로고
    • Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An introduction to the scientific issues
    • S.M. Bentzen, L.S. Constine, and J.O. Deasy Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues Int J Radiat Oncol Biol Phys 76 2010 S3 S9
    • (2010) Int J Radiat Oncol Biol Phys , vol.76
    • Bentzen, S.M.1    Constine, L.S.2    Deasy, J.O.3
  • 25
    • 84867047206 scopus 로고    scopus 로고
    • Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study
    • M.E. Christianen, C. Schilstra, and I. Beetz Predictive modelling for swallowing dysfunction after primary (chemo)radiation: results of a prospective observational study Radiother Oncol 105 2012 107 114
    • (2012) Radiother Oncol , vol.105 , pp. 107-114
    • Christianen, M.E.1    Schilstra, C.2    Beetz, I.3
  • 26
    • 84868370738 scopus 로고    scopus 로고
    • Biological mechanisms of normal tissue damage: Importance for the design of NTCP models
    • K.R. Trott, W. Doerr, and A. Facoetti Biological mechanisms of normal tissue damage: importance for the design of NTCP models Radiother Oncol 105 2012 79 85
    • (2012) Radiother Oncol , vol.105 , pp. 79-85
    • Trott, K.R.1    Doerr, W.2    Facoetti, A.3
  • 27
    • 80052286168 scopus 로고    scopus 로고
    • Late radiation-induced heart disease after radiotherapy. Clinical importance, radiobiological mechanisms and strategies of prevention
    • N. Andratschke, J. Maurer, M. Molls, and K.R. Trott Late radiation-induced heart disease after radiotherapy. Clinical importance, radiobiological mechanisms and strategies of prevention Radiother Oncol 100 2011 160 166
    • (2011) Radiother Oncol , vol.100 , pp. 160-166
    • Andratschke, N.1    Maurer, J.2    Molls, M.3    Trott, K.R.4


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