Biomarkers and Surrogate Endpoints for Normal-Tissue Effects of Radiation Therapy: The Importance of Dose-Volume Effects

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 3 SUPPL., 2010, Pages

  Bentzen, Søren M ^a,b   Parliament, Matthew ^c   Deasy, Joseph O ^d   Dicker, Adam ^b,e   Curran, Walter J ^e,f   Williams, Jacqueline P ^g   Rosenstein, Barry S ^h  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b RADIATION THERAPY ONCOLOGY GROUP   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^h NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biomarkers; Dose distribution; Normal tissue effects; Predictive factors; Radiogenomics; Single nucleotide polymorphisms; Surrogate endpoints; Toxicity

Indexed keywords

DOSE DISTRIBUTIONS; NORMAL TISSUE; PREDICTIVE FACTORS; RADIOGENOMICS; SINGLE NUCLEOTIDE POLYMORPHISMS;

BIOMARKERS; MOLECULAR BIOLOGY; NUCLEOTIDES; POLYMORPHISM; RADIATION EFFECTS; RADIOTHERAPY; TISSUE; TOXICITY;

NORMAL DISTRIBUTION;

BIOLOGICAL MARKER; CYTOKINE; GROWTH FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CANCER RADIOTHERAPY; FIBROBLAST; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MONITORING; ORGAN SIZE; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIATION DOSE FRACTIONATION; RADIATION INJURY; RADIATION RESPONSE; RADIOSENSITIVITY; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; THERAPY EFFECT; TISSUE INJURY;

BIOLOGICAL MARKERS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RADIATION INJURIES; RADIATION TOLERANCE; RADIOTHERAPY; TERMINOLOGY AS TOPIC; TRANSFORMING GROWTH FACTOR BETA1;

EID: 76449112804     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.08.076     Document Type: Article

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