-
1
-
-
33646366173
-
Notch1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
-
Grabher C, von Boehmer H, Look AT. Notch1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev 2006;6:347-59.
-
(2006)
Nat Rev
, vol.6
, pp. 347-359
-
-
Grabher, C.1
von Boehmer, H.2
Look, A.T.3
-
2
-
-
79951516547
-
Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia
-
Paganin M, Ferrando A. Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia. Blood Rev 2011;25:83-90.
-
(2011)
Blood Rev
, vol.25
, pp. 83-90
-
-
Paganin, M.1
Ferrando, A.2
-
3
-
-
78649991073
-
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
-
Aster JC, Blacklow SC, Pear WS. Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies. J Pathol 2011;223:262-73.
-
(2011)
J Pathol
, vol.223
, pp. 262-273
-
-
Aster, J.C.1
Blacklow, S.C.2
Pear, W.S.3
-
4
-
-
0023856341
-
Clinical and biologic characterization of T-cell neoplasias with rearrangements of chromosome 7 band q34
-
Smith SD, Morgan R, Gemmell R, Amylon MD, Link MP, Linker C, Hecht BK, Warnke R, Glader BE, Hecht F. Clinical and biologic characterization of T-cell neoplasias with rearrangements of chromosome 7 band q34. Blood 1988;71:395-402.
-
(1988)
Blood
, vol.71
, pp. 395-402
-
-
Smith, S.D.1
Morgan, R.2
Gemmell, R.3
Amylon, M.D.4
Link, M.P.5
Linker, C.6
Hecht, B.K.7
Warnke, R.8
Glader, B.E.9
Hecht, F.10
-
5
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen LW, Bird J, West DC, Soreng AL, Reynolds TC, Smith SD, Sklar J. TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991;66:649-61.
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
6
-
-
33745203104
-
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors
-
Palomero T, Barnes KC, Real PJ, Glade Bender JL, Sulis ML, Murty VV, Colovai AI, Balbin M, Ferrando AA. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors. Leukemia 2006;20:1279-87.
-
(2006)
Leukemia
, vol.20
, pp. 1279-1287
-
-
Palomero, T.1
Barnes, K.C.2
Real, P.J.3
Glade Bender, J.L.4
Sulis, M.L.5
Murty, V.V.6
Colovai, A.I.7
Balbin, M.8
Ferrando, A.A.9
-
7
-
-
20144363957
-
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
-
Speleman F, Cauwelier B, Dastugue N, et al. A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias. Leukemia 2005;19:358-66.
-
(2005)
Leukemia
, vol.19
, pp. 358-366
-
-
Speleman, F.1
Cauwelier, B.2
Dastugue, N.3
-
8
-
-
84871247871
-
-
eds. Mitelman database of chromosome aberrations and gene fusions in cancer. Updated on May 21, 2012. Available from: (accessed on 15th June, 2012).
-
Mitelman F, Johansson B, Mertens F, eds. Mitelman database of chromosome aberrations and gene fusions in cancer. 2012. Updated on May 21, 2012. Available from: http://cgap.nci.nih.gov/Chromosomes/Mitelman. (accessed on 15th June, 2012).
-
(2012)
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
9
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear WS, Aster JC, Scott ML, Hasserjian RP, Soffer B, Sklar J, Baltimore D. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med 1996;183:2283-91.
-
(1996)
J Exp Med
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
Baltimore, D.7
-
10
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, Morris JP IV, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306:269-71.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris IV, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
11
-
-
70350104056
-
T lymphoblastic leukaemia/lymphoma
-
Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, eds., 4th edn. Lyon: International Agency for Research on Cancer;: -
-
Borowitz MJ, Chan JKC. T lymphoblastic leukaemia/lymphoma. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, eds. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues, 4th edn. Lyon: International Agency for Research on Cancer; 2008:176-8.
-
(2008)
WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues
, pp. 176-178
-
-
Borowitz, M.J.1
Chan, J.K.C.2
-
12
-
-
78549295157
-
Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia: the JALSG-ALL97 study
-
Jinnai I, Sakura T, Tsuzuki M, et al. Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia: the JALSG-ALL97 study. Int J Hematol 2010;92:490-502.
-
(2010)
Int J Hematol
, vol.92
, pp. 490-502
-
-
Jinnai, I.1
Sakura, T.2
Tsuzuki, M.3
-
14
-
-
67349199132
-
A second NOTCH1 chromosome rearrangement: t(9;14)(q34.3;q11.2) in T-cell neoplasia
-
Suzuki S, Nagel S, Schneider B, Chen S, Kaufmann M, Uozumi K, Arima N, Drexler HG, MacLeod RAF. A second NOTCH1 chromosome rearrangement: t(9;14)(q34.3;q11.2) in T-cell neoplasia. Leukemia 2009;23:1003-6.
-
(2009)
Leukemia
, vol.23
, pp. 1003-1006
-
-
Suzuki, S.1
Nagel, S.2
Schneider, B.3
Chen, S.4
Kaufmann, M.5
Uozumi, K.6
Arima, N.7
Drexler, H.G.8
MacLeod, R.A.F.9
-
15
-
-
78650335900
-
Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1
-
Ashworth TD, Pear WS, Chiang MY, Blacklow SC, Mastio J, Xu L, Kelliher M, Kastner P, Chan S, Aster JC. Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1. Blood 2010;116:5455-64.
-
(2010)
Blood
, vol.116
, pp. 5455-5464
-
-
Ashworth, T.D.1
Pear, W.S.2
Chiang, M.Y.3
Blacklow, S.C.4
Mastio, J.5
Xu, L.6
Kelliher, M.7
Kastner, P.8
Chan, S.9
Aster, J.C.10
-
16
-
-
78650379575
-
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
-
Jeannet R, Mastio J, Macias-Garcia A, et al. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood 2010;116:5443-54.
-
(2010)
Blood
, vol.116
, pp. 5443-5454
-
-
Jeannet, R.1
Mastio, J.2
Macias-Garcia, A.3
-
17
-
-
84861842411
-
An activating intragenic deletion in NOTCH1 in human T-ALL
-
Haydu JE, Keersmaecker KD, Duff MK, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Ferrando A. An activating intragenic deletion in NOTCH1 in human T-ALL. Blood 2012;119:5211-4.
-
(2012)
Blood
, vol.119
, pp. 5211-5214
-
-
Haydu, J.E.1
Keersmaecker, K.D.2
Duff, M.K.3
Paietta, E.4
Racevskis, J.5
Wiernik, P.H.6
Rowe, J.M.7
Ferrando, A.8
-
18
-
-
1942533477
-
Detection and evaluation of intron retention events in the human transcriptome
-
Galante PA, Sakabe NJ, Kirschbaum-Slager N, De Souza SJ. Detection and evaluation of intron retention events in the human transcriptome. RNA 2004;10:757-65.
-
(2004)
RNA
, vol.10
, pp. 757-765
-
-
Galante, P.A.1
Sakabe, N.J.2
Kirschbaum-Slager, N.3
De Souza, S.J.4
-
19
-
-
84859441129
-
Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy
-
Onozawa M, Aplan PD. Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy. Genes Chromosom Cancer 2012;51:525-35.
-
(2012)
Genes Chromosom Cancer
, vol.51
, pp. 525-535
-
-
Onozawa, M.1
Aplan, P.D.2
-
20
-
-
0024365538
-
Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation
-
Roth DB, Chang XB, Wilson JH. Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation. Mol Cell Biol 1989;9:3049-57.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 3049-3057
-
-
Roth, D.B.1
Chang, X.B.2
Wilson, J.H.3
-
21
-
-
84863786154
-
Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia
-
Samon JB, Castillo-Martin M, Hadler M, et al. Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia. Mol Cancer Ther 2012;11:1565-75.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1565-1575
-
-
Samon, J.B.1
Castillo-Martin, M.2
Hadler, M.3
|