Detection of genotoxic and non-genotoxic carcinogens in Xpc-/-p53+/- mice

Toxicology and Applied Pharmacology

Volumn 266, Issue 2, 2013, Pages 289-297

  Melis, Joost P M ^a,b   Speksnijder, Ewoud N ^b   Kuiper, Raoul V ^a,c   Salvatori, Daniela C F ^b   Schaap, Mirjam M ^a,b   Maas, Saskia ^b   Robinson, Joke ^a   Verhoef, Aart ^a   van Benthem, Jan ^a   Luijten, Mirjam ^a   van Steeg, Harry ^a,b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Carcinogenicity testing; DNA repair; Genotoxic carcinogen; Non genotoxic carcinogen; P53 tumor suppressor gene; Risk assessment; Xpc

Indexed keywords

CARCINOGEN; PROTEIN P53; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGEN TESTING; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENOTOXICITY; HUMAN; IN VIVO STUDY; LIVER CELL; MALE; MOUSE; NONHUMAN;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA-BINDING PROTEINS; FEMALE; GENES, P53; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENICITY TESTS; MUTAGENS; PILOT PROJECTS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

ANIMALIA; MURINAE; MUS; RODENTIA;

EID: 84871139229     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.11.004     Document Type: Article

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