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Volumn 8, Issue ISSUE A, 2010, Pages 171-183

A primary cause of cancer: GABA deficiency in endocrine pancreas

(1)  Israël, Maurice a,b  

a CNRS *  (France)
b CNRS   (France)

Author keywords

Alpha cells; Beta cells; Betel nuts; Cancer cause; Delta cells; GABA; GAD; Glucagon; Guvacoline; Gyromitrin; IGF; Insulin; Maize; Nipecotic; Nutrition cancer; Pancreas; Pellagra; PP2A; Pyrroles; Pyrrolizidine; Roundup; Somatostatin; Vitamin B6; Zn2+

Indexed keywords

4 AMINOBUTYRIC ACID; ADRENALIN; CHOLINE DERIVATIVE; CORTICOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GLUCAGON; GLUTAMATE DECARBOXYLASE; GYROMITRINE; HEXOKINASE; HYDRAZINE DERIVATIVE; HYDROCORTISONE; INDOLEAMINE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PYRIDOXINE; PYRROLIZIDINE ALKALOID; SOMATOMEDIN; SOMATOSTATIN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG; ZINC ION;

EID: 84871118048     PISSN: 15439135     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (44)
  • 2
    • 0034433697 scopus 로고    scopus 로고
    • Glucagon is an ACTH secretagogue as effective as hCRH after intramuscular administration while it is ineffective when given intravenously in normal subjects
    • Arvat E, Maccagno B, Ramunni J, Giordano R, DiVito L, Broglio F, Maccario M, Camanni F, Ghigo E (2000)Glucagon is an ACTH secretagogue as effective as hCRH after intramuscular administration while it is ineffective when given intravenously in normal subjects. Pituitary 3(3), 169-73.
    • (2000) Pituitary , vol.3 , Issue.3 , pp. 169-173
    • Arvat, E.1    Maccagno, B.2    Ramunni, J.3    Giordano, R.4    DiVito, L.5    Broglio, F.6    Maccario, M.7    Camanni, F.8    Ghigo, E.9
  • 3
    • 56049086867 scopus 로고    scopus 로고
    • Insulin as a physiological modulator of glucagon secretion
    • Bansal P, Wang Q (2008)Insulin as a physiological modulator of glucagon secretion. Am J Physiol Endocrinol Metab 295, E751-E761.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Bansal, P.1    Wang, Q.2
  • 6
    • 0036155780 scopus 로고    scopus 로고
    • Metabolic effects of the consumption of Areca catechu
    • Boucher BJ, Mannan N (2002) Metabolic effects of the consumption of Areca catechu. Addiction Biology 7, 103-110.
    • (2002) Addiction Biology , vol.7 , pp. 103-110
    • Boucher, B.J.1    Mannan, N.2
  • 7
    • 34547903288 scopus 로고    scopus 로고
    • The biological significance of cancer: Mitochondria as a cause of cancer and theinhibition of glycolysis with citrate as a cancer treatment
    • Bucay AH (2007)The biological significance of cancer: Mitochondria as a cause of cancer and theinhibition of glycolysis with citrate as a cancer treatment. Medical Hypotheses 69, 826-828.
    • (2007) Medical Hypotheses , vol.69 , pp. 826-828
    • Bucay, A.H.1
  • 8
    • 0020378508 scopus 로고
    • The available niacin values of foods for rats and their relation to analytical values
    • Carter E-GA, Carpenter K-J (1982)The available niacin values of foods for rats and their relation to analytical values. J Nutr 112(11), 2091-103.
    • (1982) J Nutr , vol.112 , Issue.11 , pp. 2091-2103
    • Carter, E.-G.A.1    Carpenter, K.-J.2
  • 10
    • 77951820378 scopus 로고    scopus 로고
    • Ultrastructural alterations in liver of mice exposed chronically and transgenerationally to aqueous extract of betel nut. Implications in betel nut-induced carcinogenesis
    • Choudhury Y, Sharan RN (2010)Ultrastructural alterations in liver of mice exposed chronically and transgenerationally to aqueous extract of betel nut. Implications in betel nut-induced carcinogenesis: Microsc Res Tech 73(5), 530-9.
    • (2010) Microsc Res Tech , vol.73 , Issue.5 , pp. 530-539
    • Choudhury, Y.1    Sharan, R.N.2
  • 11
    • 29344472907 scopus 로고
    • Action of Phenylpyrazole Insecticides at the GABA-Gated Chloride Channel
    • Cole LM, Nicholson RA, Casida JE (1993) Action of Phenylpyrazole Insecticides at the GABA-Gated Chloride Channel. Pestic. Biochem. Physiol 46, 47-54.
    • (1993) Pestic. Biochem. Physiol , vol.46 , pp. 47-54
    • Cole, L.M.1    Nicholson, R.A.2    Casida, J.E.3
  • 12
    • 37349051136 scopus 로고    scopus 로고
    • Toxicity and effects of a glyphosate-based herbicide on the Neotropical fish Prochilodus lineatus
    • Part C
    • Do Carmo Langiano V, Martinez C.B. R (2008)Toxicity and effects of a glyphosate-based herbicide on the Neotropical fish Prochilodus lineatus. Comparative Biochemistry and Physiology Part C147, 222-231.
    • (2008) Comparative Biochemistry and Physiology , vol.147 , pp. 222-231
    • Do Carmo Langiano, V.1    Martinez, C.B.R.2
  • 16
    • 84871158854 scopus 로고    scopus 로고
    • Fipronil Third Reevaluation-Report of the Hazard Identification Assessment Review Committee; HED Doc. No. 014400; U.S. Environmental Protection Agency, U.S. Government Printing Office: Washington, DC, 1-24. Gyromitrin
    • Fipronil Third Reevaluation-Report of the Hazard Identification Assessment Review Committee; HED Doc. No. 014400; U.S. (2000)Environmental Protection Agency, Health Effects Division, U.S. Government Printing Office: Washington, DC, 1-24. Gyromitrin [http://en.wikipedia.org/wiki/Gyromitrin]
    • (2000) Health Effects Division
  • 17
    • 84864803714 scopus 로고    scopus 로고
    • A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells
    • Icard P, Lincet H (2012)A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells. Biochimica et Biophysica Acta 1826, 423-433.
    • (2012) Biochimica et Biophysica Acta , vol.1826 , pp. 423-433
    • Icard, P.1    Lincet, H.2
  • 18
    • 84865793246 scopus 로고    scopus 로고
    • A possible primary cause of cancer: Deficient cellular interactions in endocrine pancreas
    • Israël M (2012a) A possible primary cause of cancer: deficient cellular interactions in endocrine pancreas. Molecular Cancer 11, 63-8.
    • (2012) Molecular Cancer , vol.11 , pp. 63-68
    • Israël, M.1
  • 19
    • 84857162763 scopus 로고    scopus 로고
    • On the origin of cancers by means of metabolic election: Tumor cell targets
    • (Aligarh) Special Issue: Cancer Metabolism
    • Israël M (2012b) On the origin of cancers by means of metabolic election: Tumor cell targets. Biomedical Research (Aligarh) 23, (SI 5-8) Special Issue: Cancer Metabolism.
    • (2012) Biomedical Research , vol.23 , Issue.SI 5-8
    • Israël, M.1
  • 20
    • 79957941802 scopus 로고    scopus 로고
    • The metabolic advantage of tumor cells
    • Israël M, Schwartz L (2011a) The metabolic advantage of tumor cells. Mol Cancer 10, (70), 1-12.
    • (2011) Mol Cancer , vol.10 , Issue.70 , pp. 1-12
    • Israël, M.1    Schwartz, L.2
  • 21
    • 84855458438 scopus 로고    scopus 로고
    • On the metabolic origin of cancer: Substances that target tumor metabolism
    • (Aligarh)
    • Israël M, Schwartz L (2011b) On the metabolic origin of cancer: Substances that target tumor metabolism. Biomedical Research (Aligarh) 22(2), 130-164.
    • (2011) Biomedical Research , vol.22 , Issue.2 , pp. 130-164
    • Israël, M.1    Schwartz, L.2
  • 24
    • 21744452669 scopus 로고    scopus 로고
    • Pyridoxine in clinical toxicology: A review
    • Lheureux P, Penaloza A, Gris M (2005) Pyridoxine in clinical toxicology: a review. Eur J Emerg Med 12 (2), 78-85.
    • (2005) Eur J Emerg Med , vol.12 , Issue.2 , pp. 78-85
    • Lheureux, P.1    Penaloza, A.2    Gris, M.3
  • 25
    • 84857171789 scopus 로고    scopus 로고
    • Pyruvate kinase M2: A key enzyme of the tumor metabolome andits medical relevance
    • (Aligarh)
    • Mazurek S (2012)Pyruvate kinase M2: A key enzyme of the tumor metabolome andits medical relevance. Biomedical Research (Aligarh) 23(2), SI 133-SI 141.
    • (2012) Biomedical Research , vol.23 , Issue.2
    • Mazurek, S.1
  • 27
    • 84861458044 scopus 로고    scopus 로고
    • Exposure to glyphosateand/ orMn/Zn-ethylene-bis-dithiocarbamatecontaining pesticides leads to degeneration of gamma-aminobutyric acid and dopamine neurons in Caenorhabditis elegans
    • Negga R, Stuart JA, Machen ML, Salva J. Lizek AJ, Richardson SJ, Osborne AS, Mirallas O, McVey KA, Fitsanakis VA (2012) Exposure to glyphosateand/ orMn/Zn-ethylene-bis-dithiocarbamatecontaining pesticides leads to degeneration of gamma-aminobutyric acid and dopamine neurons in Caenorhabditis elegans. Neurotox Res. 21(3), 281-90.
    • (2012) Neurotox Res. , vol.21 , Issue.3 , pp. 281-290
    • Negga, R.1    Stuart, J.A.2    Machen, M.L.3    Salva, J.4    Lizek, A.J.5    Richardson, S.J.6    Osborne, A.S.7    Mirallas, O.8    McVey, K.A.9    Fitsanakis, V.A.10
  • 28
    • 0036091597 scopus 로고    scopus 로고
    • Choline deficiency associated with diethanolamine carcinogenicity. (Toxicological highlights)
    • Nixtamalization
    • Newberne PM (2002)Choline deficiency associated with diethanolamine carcinogenicity. (Toxicological highlights). Toxicological sciences 67, 1-3.
    • (2002) Toxicological sciences , vol.67 , pp. 1-3
    • Newberne, P.M.1
  • 29
    • 84857158310 scopus 로고    scopus 로고
    • Alternative splicing rewires cellular metabolism to turn on the Warburg effect
    • SI 25-SI 30
    • Palazzo AF, Mahadevan K (2012)Alternative splicing rewires cellular metabolism to turn on the Warburg effect. Biomedical Research (Aligarh), 23(2), SI 25-SI 30.
    • (2012) Biomedical Research (Aligarh) , vol.23 , Issue.2
    • Palazzo, A.F.1    Mahadevan, K.2
  • 30
    • 84862236225 scopus 로고    scopus 로고
    • Anti-Yo and antiglutamic acid decarboxylase antibodies presenting in carcinoma of the uterus with paraneoplastic cerebellar degeneration: A case report
    • Panegyres PK, Graves A (2012)Anti-Yo and antiglutamic acid decarboxylase antibodies presenting in carcinoma of the uterus with paraneoplastic cerebellar degeneration: a case report. Journal of Medical Case Reports 6, 155-8.
    • (2012) Journal of Medical Case Reports , vol.6 , pp. 155-158
    • Panegyres, P.K.1    Graves, A.2
  • 31
    • 84871125902 scopus 로고    scopus 로고
    • Analyse d'échantillons alimentaires pour la presence d'organismes génétiquement modifiés Module 7 caractéristiques du soja Roundup Ready, du maïs MON810 et du maïs Bt-176
    • JRC European commission (see page 15 and Figure 8)
    • Querci M, Mazzara M Analyse d'échantillons alimentaires pour la presence d'organismes génétiquement modifiés Module 7 caractéristiques du soja Roundup Ready, du maïs MON810 et du maïs Bt-176. JRC European commission 1-20 (see page 15 and Figure 8)
    • Querci, M.1    Mazzara, M.2
  • 33
    • 77950841021 scopus 로고    scopus 로고
    • A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results
    • Schwartz L, Abolhassani M, Guais A, Sanders E, Steyaert JM, Campion F, Israël M. (2010) A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results. Oncology reports 23, 1407-16.
    • (2010) Oncology reports , vol.23 , pp. 1407-1416
    • Schwartz, L.1    Abolhassani, M.2    Guais, A.3    Sanders, E.4    Steyaert, J.M.5    Campion, F.6    Israël, M.7
  • 35
    • 0031438061 scopus 로고    scopus 로고
    • Nutrient regulation of gamma-aminobutyric acid release from islet beta cells
    • Smismans A, Schuit F, Pipeleers D (1997) Nutrient regulation of gamma-aminobutyric acid release from islet beta cells. Diabetologia; 40, 1411-1415
    • (1997) Diabetologia , vol.40 , pp. 1411-1415
    • Smismans, A.1    Schuit, F.2    Pipeleers, D.3
  • 36
    • 0025781922 scopus 로고
    • Autoimmunity to glutamic acid decarboxylase (GAD) in stiff-man syndrome and insulin-dependent diabetes mellitus
    • Solimena M, De Camilli P (1991)Autoimmunity to glutamic acid decarboxylase (GAD) in stiff-man syndrome and insulin-dependent diabetes mellitus. Trends Neurosci 14, 452-7.
    • (1991) Trends Neurosci , vol.14 , pp. 452-457
    • Solimena, M.1    de Camilli, P.2
  • 37
    • 0018692168 scopus 로고
    • Effect of Norepinephrin on insulin, glucagon, and somatostatin secretion in isolated perifused rat islets
    • Sorenson RL, Elde RP, Seybold V (1979) Effect of Norepinephrin on insulin, glucagon, and somatostatin secretion in isolated perifused rat islets. Diabetes 28(10), 899-904.
    • (1979) Diabetes , vol.28 , Issue.10 , pp. 899-904
    • Sorenson, R.L.1    Elde, R.P.2    Seybold, V.3
  • 38
    • 0018389156 scopus 로고
    • Carcinogenic effects in Syrian golden hamster of N-methyl-N-formylhydrazine of the false morel mushroom Gyromitra esculenta
    • Toth B, Patil K (1979)Carcinogenic effects in Syrian golden hamster of N-methyl-N-formylhydrazine of the false morel mushroom Gyromitra esculenta. J Cancer Res Clin Oncol 93(2), 109-21.
    • (1979) J Cancer Res Clin Oncol , vol.93 , Issue.2 , pp. 109-121
    • Toth, B.1    Patil, K.2
  • 39
    • 0037042211 scopus 로고    scopus 로고
    • Protein phosphatase2A methylation: A link between elevated plasma homocysteine and Alzheimer's disease
    • Vafai SB, Stock JB (2002)Protein phosphatase2A methylation: a link between elevated plasma homocysteine and Alzheimer's disease. FEBS Lett 518(1-3), 1-4.
    • (2002) FEBS Lett , vol.518 , Issue.1-3 , pp. 1-4
    • Vafai, S.B.1    Stock, J.B.2
  • 40
    • 1842422955 scopus 로고    scopus 로고
    • Glucose inhibition of glucagon secretion from rat α-cells is mediated by GABAreleased from neighboring β-cells
    • Wendt A, Birnir B, Buschard K, Gromada J, Salehi A, Sewing S, Rorsman P, Braun M (2004) Glucose inhibition of glucagon secretion from rat α-cells is mediated by GABAreleased from neighboring β-cells. Diabetes 53(4), 1038-1045.
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1038-1045
    • Wendt, A.1    Birnir, B.2    Buschard, K.3    Gromada, J.4    Salehi, A.5    Sewing, S.6    Rorsman, P.7    Braun, M.8
  • 41
    • 0017327362 scopus 로고
    • Excretion of pyrrolic metabolites in the bile of rats given the pyrrolizidine alkaloid retrorsine or the bis-N-etylcarbamate of synthanecine A
    • White IN (1977)Excretion of pyrrolic metabolites in the bile of rats given the pyrrolizidine alkaloid retrorsine or the bis-N-etylcarbamate of synthanecine A. Chem Biol Interact 16(2), 169-80.
    • (1977) Chem Biol Interact , vol.16 , Issue.2 , pp. 169-180
    • White, I.N.1
  • 43
    • 59849102484 scopus 로고    scopus 로고
    • Impact of chewing betel-nut (Areca catechu) on liver cirrhosis and hepatocellular carcinoma: A population study from an area with a high prevalence of hepatitis B and C infections
    • Wu G H-M, Boucher BJ, Chiu Y-H, Liao C-S, Chen T H-H (2008)Impact of chewing betel-nut (Areca catechu) on liver cirrhosis and hepatocellular carcinoma: a population study from an area with a high prevalence of hepatitis B and C infections. Public health Nutrition; 12(1), 129-135
    • (2008) Public health Nutrition; , vol.12 , Issue.1 , pp. 129-135
    • Wu, G.H.-M.1    Boucher, B.J.2    Chiu, Y.-H.3    Liao, C.-S.4    Chen, T.H.-H.5
  • 44
    • 0035871866 scopus 로고    scopus 로고
    • GABA Transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the transporter GABA
    • Wu Y, Wengagn W, Richerson GB (2001) GABA Transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the transporter GABA. The Journal of Neuroscience 21(8), 2630-9
    • (2001) The Journal of Neuroscience , vol.21 , Issue.8 , pp. 2630-2639
    • Wu, Y.1    Wengagn, W.2    Richerson, G.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.