Glucagon is an ACTH secretagogue as effective as hCRH after intramuscolar administration while it is ineffective when given intravenously in normal subjects

Pituitary

Volumn 3, Issue 3, 2000, Pages 169-173

  Arvat, Emanuela ^a   Maccagno, Barbara ^a   Ramunni, Josefina ^a   Giordano, Roberta ^a   DiVito, Lidia ^a   Broglio, Fabio ^a   Maccario, Mauro ^a   Camanni, Franco ^a   Ghigo, Ezio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

ACTH; Cortisol; GH; Glucagon; Humans

Indexed keywords

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; GLUCAGON; GLUCOSE; GROWTH HORMONE; HYDROCORTISONE; PLACEBO;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EVALUATION; FEMALE; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; HYPOPHYSIS ADRENAL SYSTEM; NAUSEA; NORMAL HUMAN; OBSERVATION; PRIORITY JOURNAL; SIDE EFFECT; STATISTICAL ANALYSIS; STRESS; TACHYCARDIA;

ADRENOCORTICOTROPIC HORMONE; ADULT; BLOOD GLUCOSE; CORTICOTROPIN-RELEASING HORMONE; FEMALE; GASTROINTESTINAL DISEASES; GLUCAGON; HUMAN GROWTH HORMONE; HUMANS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; REFERENCE VALUES; TACHYCARDIA;

EID: 0034433697     PISSN: 1386341X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011451710004     Document Type: Article

References (24)

1. Growth-hormone release by glucagon
2. Glucagon stimulation of human growth hormone
3. Growth hormone response to intramuscular glucagon
4. Subcutaneous glucagon as a test of the ability of the pituitary to secrete GH and ACTH
5. Intramuscular glucagon as a provocative stimulus for the assessment of pituitary function: Growth hormone and cortisol responses
6. A comparison of the insulin tolerance/glucagon test with the short ACTH stimulation test in the assessment of the hypothalamo-pituitary-adrenal axis in the early post-operative period after hypophysectomy
7. Comparison of the diagnostic utility of the simplified and standard i.m. glucagon stimulation test
8. A review of growth hormone stimulation tests in children
9. Hypoglycemia: A potent stimulus to secretion of growth hormone
10. Glucagon stimulates GH secretion after intramuscular but not intravenous administration. Evidence against the assumption that glucagon per se has a GH-releasing activity
11. ACTH-releasing effect of glucagon in humans. Interaction with hCRH, AVP and Hexarelin
12. About the effects of glucagon on growth hormone release
13. About the effects of glucagon on growth hormone release
14. Plasma glucose, non-esterified fatty acid, insulin and growth hormone response to glucagon in the newborn
15. The early rise of plasma growth hormone (HGH) and immunoreactive insulin (IRI) in children following intravenous glucagon
16. Glucagon-induced growth hormone release in children
17. Corticotropin-releasing hormone in humans
18. Glucagon and energetic substrates
19. Studies on the effect of glucagon on the human sympatho-adrenal system
20. Neurotransmitter regulation of the anterior pituitary
21. Effect of exogenous glucagon on pituitary polypeptide hormone release
22. Distribution of GLP-I bindings sites for GLP-1(7-36)amide on the posterior lobe of the rat pituitary
23. Central administration of glucagon-like-peptide-1 activates hypothalamic neuroendocrine neurons in the rat
24. The central corticotropin-releasing factor and glucagon-like peptide-1 in food intake of the neonatal chick