Changes in dermal interstitial ATP levels during local heating of human skin

Journal of Physiology

Volumn 590, Issue 24, 2012, Pages 6403-6411

  Gifford, Jayson R ^a,b,c   Heal, Cory ^a   Bridges, Jarom ^a   Goldthorpe, Scott ^a   Mack, Gary W ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; LUCIFERASE;

ADULT; ARTICLE; BIOACCUMULATION; BODY TEMPERATURE SENSATION; DIALYSATE; FEMALE; HEATING; HUMAN; HUMAN EXPERIMENT; INTERSTITIAL FLUID; MALE; MICRODIALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD FLOW; SKIN BLOOD VESSEL; SKIN CONDUCTANCE; SKIN TEMPERATURE; THERMAL ANALYSIS;

ADENOSINE TRIPHOSPHATE; ADULT; ANALYSIS OF VARIANCE; FEMALE; FOREARM; HUMANS; HYPERAMMONEMIA; HYPERTHERMIA, INDUCED; LEAST-SQUARES ANALYSIS; LINEAR MODELS; LOGISTIC MODELS; MALE; MICRODIALYSIS; REGIONAL BLOOD FLOW; SKIN; SKIN TEMPERATURE; THERMOSENSING; TIME FACTORS; TRPV CATION CHANNELS; VASODILATION; YOUNG ADULT;

EID: 84871067859     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.240523     Document Type: Article

References (33)

1. Alvarez GE, Zhao K, Kosiba WA & Johnson JM (2006). Relative roles of local and reflex components in cutaneous vasoconstriction during skin cooling in humans. J Appl Physiol 100, 2083-2088.
2. Burnstock G, Knight GE & Greig AVH (2012). Purinergic signaling in healthy and diseased skin. J Investig Dermatol 132, 526-546.
3. Burrell HE, Wlodarski B, Foster BJ, Buckley KA, Sharpe GR, Quayle JM, Simpson AWM & Gallagher JA (2005). Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface. J Biol Chem 280, 29667-29676.
4. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD & Julius D (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816-824.
5. Charkoudian N (2003). Skin blood flow in adult human thermoregulation: How it works, when it does not, and why. Mayo Clinic Proc 78, 603-612.
6. Chung MK, Lee H, Mizuno A, Suzuki M & Caterina MJ (2004). TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes. J Biol Chem 279, 21569-21575.
7. Dixon CJ, Bowler WB, Littlewood-Evans A, Dillon JP, Bilbe G, Sharpe GR & Gallagher JA (1999). Regulation of epidermal homeostasis through P2Y(2) receptors. Br J Pharmacol 127, 1680-1686.
8. Fieger S & Wong B (2010). Adenosine receptor inhibition with theophylline attenuates the skin blood flow response to local heating in humans. Exp Physiol 95, 946-954.
9. Green BG, Shaffer GS & Gilmore MM (1993). Derivation and evaluation of a semantic scale of oral sensation magnitude with apparent ratio properties. Chem Senses 18, 683-702.
10. Guler AD, Lee HS, Iida T, Shimizu I, Tominaga M & Caterina M (2002). Heat-evoked activation of the ion channel, TRPV4. J Neurosci 22, 6408-6414.
11. Houghton BL, Meendering JR, Wong BJ & Minson CT (2006). Nitric oxide and noradrenaline contribute to the temperature threshold of the axon reflex response to gradual local heating in human skin. J Physiol 572, 811-820.
12. Huang SM, Li XX, Yu YY, Wang J & Caterina MJ (2011). TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation. Mol Pain 7, 37.
13. Johnson JM & Kellogg DL (2010). Local thermal control of the human cutaneous circulation. J Appl Physiol 109, 1229-1238.
14. Kellogg DL (2006). In vivo mechanisms of cutaneous vasodilation and vasoconstriction in humans during thermoregulatory challenges. J Appl Physiol 100, 1709-1718.
15. Lee K & Mack GW (2006). Role of nitric oxide in methacholine-induced sweating and vasodilation in human skin. J Appl Physiol 100, 1355-1360.
16. Magerl W & Treede RD (1996). Heat-evoked vasodilatation in human hairy skin: axon reflexes due to low-level activity of nociceptive afferents. J Physiol 497, 837-848.
17. Mandadi S, Sokabe T, Shibasaki K, Katanosaka K, Mizuno A, Moqrich A, Patapoutian A, Fukumi-Tominaga T, Mizumura K & Tominaga M (2009). TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Arch 458, 1093-1102.
18. Mihara H, Boudaka A, Sugiyama T, Moriyama Y & Tominaga M (2011). Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse oesophageal keratinocytes. J Physiol 589, 3471-3482.
19. Minson CT (2010). Thermal provocation to evaluate microvascular reactivity in human skin. J Appl Physiol 109, 1239-1246.
20. Minson CT, Berry LT & Joyner MJ (2001). Nitric oxide and neurally mediated regulation of skin blood flow during local heating. J Appl Physiol 91, 1619-1626.
21. Mortensen SP, Thaning P, Nyberg M, Saltin B & Hellsten Y (2011). Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique. J Physiol 589, 1847-1857.
22. Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P, Bevan S & Patapoutian A (2002). A heat-sensitive TRP channel expressed in keratinocytes. Science 296, 2046-2049.
23. Rowell LB (1977). Reflex control of cutaneous vasculature. J Invest Dermatol 69, 154-166.
24. Schepers RJ & Ringkamp M (2009). Thermoreceptors and thermosensitive afferents. Neurosci Biobehav Rev 33, 205-212.
25. Schepers RJ & Ringkamp M (2010). Thermoreceptors and thermosensitive afferents. Neurosci Biobehav Rev 34, 177-184.
26. Smith GD, Gunthorpe J, Kelsell RE, Hayes PD, Reilly P, Facer P, Wright JE, Jerman JC, Walhin JP, Ooi L, Egerton J, Charles KJ, Smart D, Randall AD, Anand P & Davis JB (2002). TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature 418, 186-190.
27. Stephens DP, Charkoudian N, Benevento JM, Johnson JM & Saumet JL (2001). The influence of topical capsaicin on the local thermal control of skin blood flow in humans. Am J Physiol Regul Integr Comp Physiol 281, R894-R901.
28. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI & Julius D (1998). The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21, 531-543.
29. Wingo JE, Brothers RM, Del Coso J & Crandall CG (2010). Intradermal administration of ATP does not mitigate tyramine-stimulated vasoconstriction in human skin. Am J Physiol Regul Integr Comp Physiol 298, R1417-R1420.
30. Wong BJ & Fieger SM (2010). Transient receptor potential vanilloid type-1 (TRPV-1) channels contribute to cutaneous thermal hyperaemia in humans. J Physiol 588, 4317-4326.
31. Wong BJ & Minson CT (2011). Altered thermal hyperaemia in human skin by prior desensitization of neurokinin-1 receptors. Exp Physiol 96, 599-609.
32. Zhang H, Cang C-L, Kawasaki Y, Liang L-L, Zhang Y-Q, Ji R-R & Zhao Z-Q (2007). Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKC epsilon: a novel pathway for heat hyperalgesia. J Neurosci 27, 12067-12077.
33. Zimmerman H (1997). Extracellular purine metabolism. Drug Dev Res 39, 337-352.