Molecular dynamics of paclitaxel encapsulated by salicylic acid-grafted chitosan oligosaccharide aggregates

Biomaterials

Volumn 34, Issue 7, 2013, Pages 1843-1851

  Wang, Xiao Ying ^a   Zhang, Ling ^b   Wei, Xiao Hong ^b   Wang, Qi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

Aggregation; Drug polymer interaction; Molecular dynamics; Paclitaxel; Salicylic acid grafted chitosan

Indexed keywords

AQUEOUS SOLUBILITY; CHITOSAN OLIGOSACCHARIDE; DRIVING FORCES; DRUG DELIVERY SYSTEM; DRUG ENCAPSULATION; DRUG LOADING; DRUG-POLYMER INTERACTION; HYDROGEN BONDING INTERACTIONS; HYDROPHOBIC DRUG; HYDROPHOBIC INTERACTIONS; LOW TOXICITY; MOLECULAR DYNAMICS SIMULATIONS; PACLITAXEL; POLYMERIC NANOPARTICLES; RADIAL DISTRIBUTION FUNCTIONS; SOLVENT ACCESSIBLE SURFACE AREAS; VAN DER WAALS;

AGGLOMERATION; BIOCOMPATIBILITY; BIODEGRADATION; CHITOSAN; DRUG DELIVERY; ENCAPSULATION; GRAFTING (CHEMICAL); HYDROGEN BONDS; HYDROPHOBICITY; MOLECULAR DYNAMICS; NANOPARTICLES; OLIGOSACCHARIDES; POLYMERS; SYNTHESIS (CHEMICAL); VAN DER WAALS FORCES;

LOADING;

CHITOSAN; OLIGOSACCHARIDE; PACLITAXEL; SALICYLIC ACID; SOLVENT;

ARTICLE; BIOCOMPATIBILITY; ENCAPSULATION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; PARTICLE SIZE; PRIORITY JOURNAL; SOLUBILITY; STATIC ELECTRICITY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOCOMPATIBLE MATERIALS; CHITOSAN; HYDROGEN BONDING; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; OLIGOSACCHARIDES; PACLITAXEL; SALICYLIC ACID;

EID: 84871037257     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.11.024     Document Type: Article

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