Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: A lipophilic substitute role

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 305-309

  Lo, Chih Yu ^a   Hsu, Lin Chen ^b   Chen, Min Shin ^a   Lin, Yi Jing ^a   Chen, Lih Geeng ^a   Kuo, Cheng Deng ^c   Wu, Jin Yi ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^b St Martin de Porres Hospital   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

9 O substituted berberine; Berberine; Cytotoxicity; Flowcytometric analysis; HepG2; HT 29

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTINEOPLASTIC AGENT; BERBERINE; BERBERINE DERIVATIVE; BEROLINE; CISPLATIN; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL STRAIN HEPG2; CELL STRAIN HT29; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HEPATOMA CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIPOPHILICITY; MOUSE; NONHUMAN;

ANTINEOPLASTIC AGENTS; BERBERINE; CELL PROLIFERATION; HEP G2 CELLS; HT29 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84871020246     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.098     Document Type: Article

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