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Volumn 4, Issue 1, 2013, Pages 151-158

Design and synthesis of a novel series of cyclohexyloxy-pyridyl derivatives as inhibitors of diacylglycerol acyl transferase 1

(15) Plowright, Alleyn T a Barton, Peter b Bennett, Stuart b Birch, Alan M b Birtles, Susan b Buckett, Linda K b Butlin, Roger J b Davies, Robert D M b Ertan, Anne c Gutierrez, Pablo Morentin b Kemmitt, Paul D b Leach, Andrew G b Svensson, Per H c,d Turnbull, Andrew V b Waring, Michael J b

a ASTRAZENECA R AND D (Sweden)

b ASTRAZENECA (United Kingdom)

c ASTRAZENECA R AND D (Sweden)

d ROYAL INSTITUTE OF TECHNOLOGY (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AZD 3988; CYCLOHEXYLOXYPYRIDYL DERIVATIVE; DIACYLGLYCEROL ACYLTRANSFERASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 1 INHIBITOR; ENZYME INHIBITOR; PYRIDINE DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CLEARANCE; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG SOLUBILITY; DRUG STRUCTURE; FAT TOLERANCE TEST; HUMAN; HYDROGEN BOND; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

RATTUS;

EID: 84870993766 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c2md20187a Document Type: Article

Times cited : (7)

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