메뉴 건너뛰기




Volumn 100, Issue 1, 2013, Pages 5-14

Impact of targeted neoadjuvant therapies in the treatment of solid organ tumours

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 84870941575     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.8987     Document Type: Review
Times cited : (5)

References (59)
  • 1
    • 75149145066 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): A randomised controlled superiority trial with a parallel HER2-negative cohort
    • Gianni L, Eiermann W, Semiglazov V, Manikhas A, Lluch A, Tjulandin S, et al., Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort. Lancet 2010; 375: 377-384.
    • (2010) Lancet , vol.375 , pp. 377-384
    • Gianni, L.1    Eiermann, W.2    Semiglazov, V.3    Manikhas, A.4    Lluch, A.5    Tjulandin, S.6
  • 2
    • 84857236823 scopus 로고    scopus 로고
    • Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, open-label, multicentre, phase 3 trial
    • NeoALTTO Study Team
    • Baselga J, Bradbury I, Eidtmann H, Di Cosimo S, de Azambuja E, Aura C, et al.,; NeoALTTO Study Team. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 2012; 379: 633-640.
    • (2012) Lancet , vol.379 , pp. 633-640
    • Baselga, J.1    Bradbury, I.2    Eidtmann, H.3    Di Cosimo, S.4    De Azambuja, E.5    Aura, C.6
  • 3
    • 84855297353 scopus 로고    scopus 로고
    • Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): A randomised multicentre, open-label, phase 2 trial
    • Gianni L, Pienkowski T, Im YH, Roman L, Tseng LM, Liu MC, et al., Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol 2012; 13: 25-32.
    • (2012) Lancet Oncol , vol.13 , pp. 25-32
    • Gianni, L.1    Pienkowski, T.2    Im, Y.H.3    Roman, L.4    Tseng, L.M.5    Liu, M.C.6
  • 4
    • 84856291930 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy and bevacizumab for HER2-negative breast cancer
    • German Breast Group; Arbeitsgemeinschaft Gynäkologische Onkologie-Breast Study Groups
    • von Minckwitz G, Eidtmann H, Rezai M, Fasching PA, Tesch H, Eggemann H, et al.,; German Breast Group; Arbeitsgemeinschaft Gynäkologische Onkologie-Breast Study Groups. Neoadjuvant chemotherapy and bevacizumab for HER2-negative breast cancer. N Engl J Med 2012; 366: 299-309.
    • (2012) N Engl J Med , vol.366 , pp. 299-309
    • Von Minckwitz, G.1    Eidtmann, H.2    Rezai, M.3    Fasching, P.A.4    Tesch, H.5    Eggemann, H.6
  • 6
    • 33747832155 scopus 로고    scopus 로고
    • Chronic kidney disease after nephrectomy in patients with renal cortical tumours: A retrospective cohort study
    • Huang WC, Levey AS, Serio AM, Snyder M, Vickers AJ, Raj GV, et al., Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol 2006; 7: 735-740.
    • (2006) Lancet Oncol , vol.7 , pp. 735-740
    • Huang, W.C.1    Levey, A.S.2    Serio, A.M.3    Snyder, M.4    Vickers, A.J.5    Raj, G.V.6
  • 7
    • 77949283860 scopus 로고    scopus 로고
    • Nephrectomy induced chronic renal insufficiency is associated with increased risk of cardiovascular death and death from any cause in patients with localized cT1b renal masses
    • Weight CJ, Larson BT, Fergany AF, Gao T, Lane BR, Campbell SC, et al., Nephrectomy induced chronic renal insufficiency is associated with increased risk of cardiovascular death and death from any cause in patients with localized cT1b renal masses. J Urol 2010; 183: 1317-1323.
    • (2010) J Urol , vol.183 , pp. 1317-1323
    • Weight, C.J.1    Larson, B.T.2    Fergany, A.F.3    Gao, T.4    Lane, B.R.5    Campbell, S.C.6
  • 8
    • 77956642234 scopus 로고    scopus 로고
    • Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma
    • Hellenthal NJ, Underwood W, Penetrante R, Litwin A, Zhang S, Wilding GE, et al., Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma. J Urol 2010; 184: 859-864.
    • (2010) J Urol , vol.184 , pp. 859-864
    • Hellenthal, N.J.1    Underwood, W.2    Penetrante, R.3    Litwin, A.4    Zhang, S.5    Wilding, G.E.6
  • 9
    • 84856698843 scopus 로고    scopus 로고
    • Dramatic reduction in tumor burden with neoadjuvant sunitinib prior to bilateral nephron-sparing surgery
    • Gorin MA, Ekwenna O, Soloway MS, Ciancio G,. Dramatic reduction in tumor burden with neoadjuvant sunitinib prior to bilateral nephron-sparing surgery. Urology 2012; 79: e11.
    • (2012) Urology , vol.79
    • Gorin, M.A.1    Ekwenna, O.2    Soloway, M.S.3    Ciancio, G.4
  • 10
    • 84866738517 scopus 로고    scopus 로고
    • Partial nephrectomy after neoadjuvant administration of sunitinib facilitates preservation of a solitary kidney
    • von Klot C, Becker JU, Grünwald V, Peters I, Kuczyk MA, Merseburger AS,. [Partial nephrectomy after neoadjuvant administration of sunitinib facilitates preservation of a solitary kidney.] Aktuelle Urol 2012; 43: 337-339.
    • (2012) Aktuelle Urol , vol.43 , pp. 337-339
    • Von Klot, C.1    Becker, J.U.2    Grünwald, V.3    Peters, I.4    Kuczyk, M.A.5    Merseburger, A.S.6
  • 11
    • 77951886671 scopus 로고    scopus 로고
    • Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma
    • Cowey CL, Amin C, Pruthi RS, Wallen EM, Nielsen ME, Grigson G, et al., Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma. J Clin Oncol 2010; 28: 1502-1507.
    • (2010) J Clin Oncol , vol.28 , pp. 1502-1507
    • Cowey, C.L.1    Amin, C.2    Pruthi, R.S.3    Wallen, E.M.4    Nielsen, M.E.5    Grigson, G.6
  • 12
    • 84856838102 scopus 로고    scopus 로고
    • Surgical outcomes and complications associated with presurgical tyrosine kinase inhibition for advanced renal cell carcinoma (RCC)
    • [Epub ahead of print]
    • Harshman LC, Yu RJ, Allen GI, Srinivas S, Gill HS, Chung BI,. Surgical outcomes and complications associated with presurgical tyrosine kinase inhibition for advanced renal cell carcinoma (RCC). Urol Oncol 2011; [Epub ahead of print].
    • (2011) Urol Oncol
    • Harshman, L.C.1    Yu, R.J.2    Allen, G.I.3    Srinivas, S.4    Gill, H.S.5    Chung, B.I.6
  • 13
    • 33745726677 scopus 로고    scopus 로고
    • Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer
    • MAGIC Trial Participants
    • Cunningham D, Allum WH, Stenning SP, Thompson JN, Van de Velde CJ, Nicolson M,; MAGIC Trial Participants. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006; 355: 11-20.
    • (2006) N Engl J Med , vol.355 , pp. 11-20
    • Cunningham, D.1    Allum, W.H.2    Stenning, S.P.3    Thompson, J.N.4    Van De Velde, C.J.5    Nicolson, M.6
  • 14
    • 79955576900 scopus 로고    scopus 로고
    • Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: An FNCLCC and FFCD multicenter phase III trial
    • Ychou M, Boige V, Pignon JP, Conroy T, Bouché O, Lebreton G, et al., Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III trial. J Clin Oncol 2011; 29: 1715-1721.
    • (2011) J Clin Oncol , vol.29 , pp. 1715-1721
    • Ychou, M.1    Boige, V.2    Pignon, J.P.3    Conroy, T.4    Bouché, O.5    Lebreton, G.6
  • 15
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, et al., Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010; 376: 687-697.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6
  • 16
    • 80053373702 scopus 로고    scopus 로고
    • Is there any advantage to combined trastuzumab and chemotherapy in perioperative setting her 2neu positive localized gastric adenocarcinoma?
    • Sbitti Y, Essaidi I, Debbagh A, Kadiri H, Oukabli M, Moussaid Y, et al., Is there any advantage to combined trastuzumab and chemotherapy in perioperative setting her 2neu positive localized gastric adenocarcinoma? World J Surg Oncol 2011; 9: 112.
    • (2011) World J Surg Oncol , vol.9 , pp. 112
    • Sbitti, Y.1    Essaidi, I.2    Debbagh, A.3    Kadiri, H.4    Oukabli, M.5    Moussaid, Y.6
  • 17
    • 77956457727 scopus 로고    scopus 로고
    • Pathological complete response after neoadjuvant chemotherapy with trastuzumab-containing regimen in gastric cancer: A case report
    • Wang J, Saukel GW, Garberoglio CA, Srikureja W, Hsueh CT,. Pathological complete response after neoadjuvant chemotherapy with trastuzumab-containing regimen in gastric cancer: a case report. J Hematol Oncol 2010; 3: 31.
    • (2010) J Hematol Oncol , vol.3 , pp. 31
    • Wang, J.1    Saukel, G.W.2    Garberoglio, C.A.3    Srikureja, W.4    Hsueh, C.T.5
  • 18
    • 84870941918 scopus 로고    scopus 로고
    • National Institutes of Health [accessed 05 September 2012]
    • National Institutes of Health. A Service of the U.S. National Institutes of Health; 2012. http://www.clinicaltrials.gov [accessed 05 September 2012].
    • (2012) A Service of the U.S. National Institutes of Health
  • 19
    • 79952075689 scopus 로고    scopus 로고
    • Cetuximab in combination with chemoradiotherapy before surgery in patients with resectable, locally advanced esophageal carcinoma: A prospective, multicenter phase IB/II trial (SAKK 75/06)
    • Ruhstaller T, Pless M, Dietrich D, Kranzbuehler H, von Moos R, Moosmann P, et al., Cetuximab in combination with chemoradiotherapy before surgery in patients with resectable, locally advanced esophageal carcinoma: a prospective, multicenter phase IB/II trial (SAKK 75/06). J Clin Oncol 2011; 29: 626-631.
    • (2011) J Clin Oncol , vol.29 , pp. 626-631
    • Ruhstaller, T.1    Pless, M.2    Dietrich, D.3    Kranzbuehler, H.4    Von Moos, R.5    Moosmann, P.6
  • 20
    • 0034015511 scopus 로고    scopus 로고
    • Molecular insights into the histogenesis and pathogenesis of gastrointestinal stromal tumors
    • Rubin BP, Fletcher JA, Fletcher CD,. Molecular insights into the histogenesis and pathogenesis of gastrointestinal stromal tumors. Int J Surg Pathol 2000; 8: 5-10.
    • (2000) Int J Surg Pathol , vol.8 , pp. 5-10
    • Rubin, B.P.1    Fletcher, J.A.2    Fletcher, C.D.3
  • 21
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, et al., Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-580.
    • (1998) Science , vol.279 , pp. 577-580
    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3    Hashimoto, K.4    Nishida, T.5    Ishiguro, S.6
  • 22
    • 39149123549 scopus 로고    scopus 로고
    • Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT
    • Blanke CD, Demetri GD, von Mehren M, Heinrich MC, Eisenberg B, Fletcher JA, et al., Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT. J Clin Oncol 2008; 26: 620-625.
    • (2008) J Clin Oncol , vol.26 , pp. 620-625
    • Blanke, C.D.1    Demetri, G.D.2    Von Mehren, M.3    Heinrich, M.C.4    Eisenberg, B.5    Fletcher, J.A.6
  • 23
    • 0642368571 scopus 로고    scopus 로고
    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
    • Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, et al., Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 2003; 21: 4342-4349.
    • (2003) J Clin Oncol , vol.21 , pp. 4342-4349
    • Heinrich, M.C.1    Corless, C.L.2    Demetri, G.D.3    Blanke, C.D.4    Von Mehren, M.5    Joensuu, H.6
  • 24
    • 56749156604 scopus 로고    scopus 로고
    • Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group
    • Heinrich MC, Owzar K, Corless CL, Hollis D, Borden EC, Fletcher CD, et al., Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group. J Clin Oncol 2008; 26: 5360-5367.
    • (2008) J Clin Oncol , vol.26 , pp. 5360-5367
    • Heinrich, M.C.1    Owzar, K.2    Corless, C.L.3    Hollis, D.4    Borden, E.C.5    Fletcher, C.D.6
  • 25
    • 33746401591 scopus 로고    scopus 로고
    • KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
    • EORTC Soft Tissue and Bone Sarcoma Group; Italian Sarcoma Group; Australasian GastroIntestinal Trials Group
    • Debiec-Rychter M, Sciot R, Le Cesne A, Schlemmer M, Hohenberger P, van Oosterom AT, et al.,; EORTC Soft Tissue and Bone Sarcoma Group; Italian Sarcoma Group; Australasian GastroIntestinal Trials Group. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer 2006; 42: 1093-1103.
    • (2006) Eur J Cancer , vol.42 , pp. 1093-1103
    • Debiec-Rychter, M.1    Sciot, R.2    Le Cesne, A.3    Schlemmer, M.4    Hohenberger, P.5    Van Oosterom, A.T.6
  • 26
    • 77954319411 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • ESMO/CONTICANET/EUROBONET Consensus Panel of Experts
    • Casali PG, Blay JY,; ESMO/CONTICANET/EUROBONET Consensus Panel of Experts. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21 (Suppl 5): v98-v102.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Casali, P.G.1    Blay, J.Y.2
  • 27
    • 84861759106 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant/adjuvant imatinib mesylate for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumors: Long-term follow-up results of Radiation Therapy Oncology Group 0132
    • Wang D, Zhang Q, Blanke CD, Demetri GD, Heinrich MC, Watson JC, et al., Phase II trial of neoadjuvant/adjuvant imatinib mesylate for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumors: long-term follow-up results of Radiation Therapy Oncology Group 0132. Ann Surg Oncol 2012; 19: 1074-1080.
    • (2012) Ann Surg Oncol , vol.19 , pp. 1074-1080
    • Wang, D.1    Zhang, Q.2    Blanke, C.D.3    Demetri, G.D.4    Heinrich, M.C.5    Watson, J.C.6
  • 29
    • 34247516968 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network (NCCN) www.nccn.org/professionals/ physician-gls/pdf/sarcoma.pdf, (accessed 05 September 2012)
    • National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma; 2012. www.nccn.org/professionals/ physician-gls/pdf/sarcoma.pdf (accessed 05 September 2012).
    • (2012) NCCN Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma
  • 31
    • 84863743780 scopus 로고    scopus 로고
    • Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C)
    • Dewdney A, Cunningham D, Tabernero J, Capdevila J, Glimelius B, Cervantes A, et al., Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C). J Clin Oncol 2012; 30: 1620-1627.
    • (2012) J Clin Oncol , vol.30 , pp. 1620-1627
    • Dewdney, A.1    Cunningham, D.2    Tabernero, J.3    Capdevila, J.4    Glimelius, B.5    Cervantes, A.6
  • 32
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • SHARP Investigators Study Group
    • Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, et al.,; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390.
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3    Hilgard, P.4    Gane, E.5    Blanc, J.F.6
  • 33
    • 79953314271 scopus 로고    scopus 로고
    • Complete regression of locally advanced hepatocellular carcinoma induced by sorafenib allowing curative resection
    • Irtan S, Chopin-Laly X, Ronot M, Faivre S, Paradis V, Belghiti J, et al., Complete regression of locally advanced hepatocellular carcinoma induced by sorafenib allowing curative resection. Liver Int 2011; 31: 740-743.
    • (2011) Liver Int , vol.31 , pp. 740-743
    • Irtan, S.1    Chopin-Laly, X.2    Ronot, M.3    Faivre, S.4    Paradis, V.5    Belghiti, J.6
  • 35
    • 80052552460 scopus 로고    scopus 로고
    • Sorafenib therapy for hepatocellular carcinoma prior to liver transplant is associated with increased complications after transplant
    • Truesdale AE, Caldwell SH, Shah NL, Argo CK, Al-Osaimi AM, Schmitt TM, et al., Sorafenib therapy for hepatocellular carcinoma prior to liver transplant is associated with increased complications after transplant. Transpl Int 2011; 24: 991-998.
    • (2011) Transpl Int , vol.24 , pp. 991-998
    • Truesdale, A.E.1    Caldwell, S.H.2    Shah, N.L.3    Argo, C.K.4    Al-Osaimi, A.M.5    Schmitt, T.M.6
  • 36
    • 79955921754 scopus 로고    scopus 로고
    • FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
    • Groupe Tumeurs Digestives of Unicancer; PRODIGE Intergroup
    • Conroy T, Desseigne F, Ychou M, Bouché O, Guimbaud R, Bécouarn Y, et al.,; Groupe Tumeurs Digestives of Unicancer; PRODIGE Intergroup. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 2011; 364: 1817-1825.
    • (2011) N Engl J Med , vol.364 , pp. 1817-1825
    • Conroy, T.1    Desseigne, F.2    Ychou, M.3    Bouché, O.4    Guimbaud, R.5    Bécouarn, Y.6
  • 37
    • 78650095716 scopus 로고    scopus 로고
    • Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer: National Cancer Institute of Canada Clinical Trials Group Study PA.3
    • da Cunha Santos G, Dhani N, Tu D, Chin K, Ludkovski O, Kamel-Reid S, et al., Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer: National Cancer Institute of Canada Clinical Trials Group Study PA.3. Cancer 2010; 116: 5599-5607.
    • (2010) Cancer , vol.116 , pp. 5599-5607
    • Da Cunha Santos, G.1    Dhani, N.2    Tu, D.3    Chin, K.4    Ludkovski, O.5    Kamel-Reid, S.6
  • 38
    • 84860830887 scopus 로고    scopus 로고
    • Molecular markers of the EGFR pathway in erlotinib-treated patients with advanced pancreatic cancer (APC): Translational analyses of a randomized, cross-over AIO phase III trial
    • Meeting abstract
    • Boeck SH, Jung A, Laubender RP, Neumann J, Egg R, Goritschan C, et al., Molecular markers of the EGFR pathway in erlotinib-treated patients with advanced pancreatic cancer (APC): translational analyses of a randomized, cross-over AIO phase III trial. J Clin Oncol 2011; 29 (Suppl): 4047. Meeting abstract.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. , pp. 4047
    • Boeck, S.H.1    Jung, A.2    Laubender, R.P.3    Neumann, J.4    Egg, R.5    Goritschan, C.6
  • 39
    • 79953756460 scopus 로고    scopus 로고
    • Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
    • Collisson EA, Sadanandam A, Olson P, Gibb WJ, Truitt M, Gu S, et al., Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat Med 2011; 17: 500-503.
    • (2011) Nat Med , vol.17 , pp. 500-503
    • Collisson, E.A.1    Sadanandam, A.2    Olson, P.3    Gibb, W.J.4    Truitt, M.5    Gu, S.6
  • 40
    • 77955914277 scopus 로고    scopus 로고
    • Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205
    • Philip PA, Benedetti J, Corless CL, Wong R, O'Reilly EM, Flynn PJ, et al., Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205. J Clin Oncol 2010; 28: 3605-3610.
    • (2010) J Clin Oncol , vol.28 , pp. 3605-3610
    • Philip, P.A.1    Benedetti, J.2    Corless, C.L.3    Wong, R.4    O'Reilly, E.M.5    Flynn, P.J.6
  • 41
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Goldstein D, Hamm J, Figer A, Hecht JR, Gallinger S, et al., Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007; 25: 1960-1966.
    • (2007) J Clin Oncol , vol.25 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3    Figer, A.4    Hecht, J.R.5    Gallinger, S.6
  • 42
    • 84875870707 scopus 로고    scopus 로고
    • Gemcitabine plus erlotinib followed by capecitabine versus capecitabine plus erlotinib followed by gemcitabine in advanced pancreatic cancer: Final results of a randomised phase 3 trial of the 'Arbeitsgemeinschaft Internistische Onkologie' (AIO-PK0104)
    • [Epub ahead of print]
    • Heinemann V, Vehling-Kaiser U, Waldschmidt D, Kettner E, Märten A, Winkelmann C, et al., Gemcitabine plus erlotinib followed by capecitabine versus capecitabine plus erlotinib followed by gemcitabine in advanced pancreatic cancer: final results of a randomised phase 3 trial of the 'Arbeitsgemeinschaft Internistische Onkologie' (AIO-PK0104). Gut 2012; [Epub ahead of print].
    • (2012) Gut
    • Heinemann, V.1    Vehling-Kaiser, U.2    Waldschmidt, D.3    Kettner, E.4    Märten, A.5    Winkelmann, C.6
  • 43
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    • Van Cutsem E, Vervenne WL, Bennouna J, Humblet Y, Gill S, Van Laethem JL, et al., Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. J Clin Oncol 2009; 27: 2231-2237.
    • (2009) J Clin Oncol , vol.27 , pp. 2231-2237
    • Van Cutsem, E.1    Vervenne, W.L.2    Bennouna, J.3    Humblet, Y.4    Gill, S.5    Van Laethem, J.L.6
  • 44
    • 67349250514 scopus 로고    scopus 로고
    • Bevacizumab combined with gemcitabine and capecitabine for advanced pancreatic cancer: A phase II study
    • Javle M, Yu J, Garrett C, Pande A, Kuvshinoff B, Litwin A, et al., Bevacizumab combined with gemcitabine and capecitabine for advanced pancreatic cancer: a phase II study. Br J Cancer 2009; 100: 1842-1845.
    • (2009) Br J Cancer , vol.100 , pp. 1842-1845
    • Javle, M.1    Yu, J.2    Garrett, C.3    Pande, A.4    Kuvshinoff, B.5    Litwin, A.6
  • 45
    • 82455171860 scopus 로고    scopus 로고
    • Bevacizumab plus gemcitabine and oxaliplatin as first-line therapy for metastatic or locally advanced pancreatic cancer: A phase II trial
    • Fogelman D, Jafari M, Varadhachary GR, Xiong H, Bullock S, Ozer H, et al., Bevacizumab plus gemcitabine and oxaliplatin as first-line therapy for metastatic or locally advanced pancreatic cancer: a phase II trial. Cancer Chemother Pharmacol 2011; 68: 1431-1438.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1431-1438
    • Fogelman, D.1    Jafari, M.2    Varadhachary, G.R.3    Xiong, H.4    Bullock, S.5    Ozer, H.6
  • 46
    • 45449090215 scopus 로고    scopus 로고
    • Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: An open-label randomised phase II study
    • Spano JP, Chodkiewicz C, Maurel J, Wong R, Wasan H, Barone C, et al., Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: an open-label randomised phase II study. Lancet 2008; 371: 2101-2108.
    • (2008) Lancet , vol.371 , pp. 2101-2108
    • Spano, J.P.1    Chodkiewicz, C.2    Maurel, J.3    Wong, R.4    Wasan, H.5    Barone, C.6
  • 47
    • 80054000816 scopus 로고    scopus 로고
    • Impact of KRAS mutations on clinical outcomes in pancreatic cancer patients treated with first-line gemcitabine-based chemotherapy
    • Kim ST, Lim do H, Jang KT, Lim T, Lee J, Choi YL, et al., Impact of KRAS mutations on clinical outcomes in pancreatic cancer patients treated with first-line gemcitabine-based chemotherapy. Mol Cancer Ther 2011; 10: 1993-1999.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1993-1999
    • Kim, S.T.1    Lim Do, H.2    Jang, K.T.3    Lim, T.4    Lee, J.5    Choi, Y.L.6
  • 48
    • 79959947067 scopus 로고    scopus 로고
    • A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection
    • Wong R, Cunningham D, Barbachano Y, Saffery C, Valle J, Hickish T, et al., A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection. Ann Oncol 2011; 22: 2042-2048.
    • (2011) Ann Oncol , vol.22 , pp. 2042-2048
    • Wong, R.1    Cunningham, D.2    Barbachano, Y.3    Saffery, C.4    Valle, J.5    Hickish, T.6
  • 49
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomised phase 2 trial
    • Folprecht G, Gruenberger T, Bechstein WO, Raab HR, Lordick F, Hartmann JT, et al., Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 2010; 11: 38-47.
    • (2010) Lancet Oncol , vol.11 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3    Raab, H.R.4    Lordick, F.5    Hartmann, J.T.6
  • 51
    • 70349690209 scopus 로고    scopus 로고
    • Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
    • Okines A, Puerto OD, Cunningham D, Chau I, Van Cutsem E, Saltz L, et al., Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. Br J Cancer 2009; 101: 1033-1038.
    • (2009) Br J Cancer , vol.101 , pp. 1033-1038
    • Okines, A.1    Puerto, O.D.2    Cunningham, D.3    Chau, I.4    Van Cutsem, E.5    Saltz, L.6
  • 52
    • 59949091448 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
    • Bokemeyer C, Bondarenko I, Makhson A, Hartmann JT, Aparicio J, de Braud F, et al., Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009; 27: 663-671.
    • (2009) J Clin Oncol , vol.27 , pp. 663-671
    • Bokemeyer, C.1    Bondarenko, I.2    Makhson, A.3    Hartmann, J.T.4    Aparicio, J.5    De Braud, F.6
  • 53
    • 81055135355 scopus 로고    scopus 로고
    • Final results from PRIME: Randomized phase III study of panitumumab (pmab) with FOLFOX4 for first-line metastatic colorectal cancer (mCRC)
    • abstract 3510
    • Douillard J, Siena S, Cassidy J, Tabernero J, Burkes RL, Barugel ME, et al., Final results from PRIME: randomized phase III study of panitumumab (pmab) with FOLFOX4 for first-line metastatic colorectal cancer (mCRC). J Clin Oncol 2011; 29 (Suppl): abstract 3510.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Douillard, J.1    Siena, S.2    Cassidy, J.3    Tabernero, J.4    Burkes, R.L.5    Barugel, M.E.6
  • 54
    • 84862202017 scopus 로고    scopus 로고
    • Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gastrointestinal stromal tumors: Is it worthwhile?
    • Tielen R, Verhoef C, van Coevorden F, Gelderblom H, Sleijfer S, Hartgrink HH, et al., Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gastrointestinal stromal tumors: is it worthwhile? World J Surg Oncol 2012; 10: 111.
    • (2012) World J Surg Oncol , vol.10 , pp. 111
    • Tielen, R.1    Verhoef, C.2    Van Coevorden, F.3    Gelderblom, H.4    Sleijfer, S.5    Hartgrink, H.H.6
  • 56
    • 84863785705 scopus 로고    scopus 로고
    • Metastasectomy in renal cell cancer after neoadjuvant therapy with multi-tyrosine kinase inhibitors
    • Firek P, Richter S, Jaekel J, Brehmer B, Heidenreich A,. [Metastasectomy in renal cell cancer after neoadjuvant therapy with multi-tyrosine kinase inhibitors.] Urologe A 2012; 51: 398-402.
    • (2012) Urologe A , vol.51 , pp. 398-402
    • Firek, P.1    Richter, S.2    Jaekel, J.3    Brehmer, B.4    Heidenreich, A.5
  • 57
    • 84865001541 scopus 로고    scopus 로고
    • Metastasectomy for distant metastatic melanoma: Analysis of data from the first Multicenter Selective Lymphadenectomy Trial (MSLT-I)
    • Howard JH, Thompson JF, Mozzillo N, Nieweg OE, Hoekstra HJ, Roses DF, et al., Metastasectomy for distant metastatic melanoma: analysis of data from the first Multicenter Selective Lymphadenectomy Trial (MSLT-I). Ann Surg Oncol 2012; 19: 2547-2555.
    • (2012) Ann Surg Oncol , vol.19 , pp. 2547-2555
    • Howard, J.H.1    Thompson, J.F.2    Mozzillo, N.3    Nieweg, O.E.4    Hoekstra, H.J.5    Roses, D.F.6
  • 58
    • 84859461606 scopus 로고    scopus 로고
    • Surgery for distant melanoma metastasis
    • Leung AM, Hari DM, Morton DL,. Surgery for distant melanoma metastasis. Cancer J 2012; 18: 176-184.
    • (2012) Cancer J , vol.18 , pp. 176-184
    • Leung, A.M.1    Hari, D.M.2    Morton, D.L.3
  • 59
    • 84855197373 scopus 로고    scopus 로고
    • Surgical intervention for imatinib and sunitinib-resistant gastrointestinal stromal tumors
    • Kikuchi H, Setoguchi T, Miyazaki S, Yamamoto M, Ohta M, Kamiya K, et al., Surgical intervention for imatinib and sunitinib-resistant gastrointestinal stromal tumors. Int J Clin Oncol 2011; 16: 741-745.
    • (2011) Int J Clin Oncol , vol.16 , pp. 741-745
    • Kikuchi, H.1    Setoguchi, T.2    Miyazaki, S.3    Yamamoto, M.4    Ohta, M.5    Kamiya, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.