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Volumn 37, Issue 6, 2012, Pages 1165-1175

Behavioral and biochemical characterization of rats treated chronically with thioacetamide: Proposal of an animal model for hepatic encephalopathy associated with cirrhosis

Author keywords

5HT; Ammonia; Cirrhosis; Hepatic encephalopathy; Psychiatric deficit; Thioacetamide

Indexed keywords

4 AMINOBUTYRIC ACID; AMMONIA; GLUTAMINE; LACTULOSE; THIOACETAMIDE;

EID: 84870910252     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.1165     Document Type: Article
Times cited : (24)

References (42)
  • 1
    • 0023491118 scopus 로고
    • Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure
    • Bassett, M.L., Mullen, K.D., Skolnick, P. and Jones, E.A. (1987): Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure. Gastroenterology, 93, 1069-1077.
    • (1987) Gastroenterology , vol.93 , pp. 1069-1077
    • Bassett, M.L.1    Mullen, K.D.2    Skolnick, P.3    Jones, E.A.4
  • 2
    • 0024325161 scopus 로고
    • Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy
    • Bergeron, M., Reader, T.A., Layrargues, G.P. and Butterworth, R.F. (1989): Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy. Neurochem. Res., 14, 853-859.
    • (1989) Neurochem. Res. , vol.14 , pp. 853-859
    • Bergeron, M.1    Reader, T.A.2    Layrargues, G.P.3    Butterworth, R.F.4
  • 3
    • 0020390062 scopus 로고
    • Amino acid imbalance and hepatic encephalopathy
    • Bernardini, P. and Fischer, J.E. (1982): Amino acid imbalance and hepatic encephalopathy. Annu. Rev. Nutr., 2, 419-454.
    • (1982) Annu. Rev. Nutr. , vol.2 , pp. 419-454
    • Bernardini, P.1    Fischer, J.E.2
  • 4
    • 67149146685 scopus 로고    scopus 로고
    • Experimental models of hepatic encephalopathy: ISHEN guidelines
    • and Members of the ISHEN Commission on Experimental Models of HE
    • Butterworth, R.F., Norenberg, M.D., Felipo, V., Ferenci, P., Albrecht, J., Blei, A.T. and Members of the ISHEN Commission on Experimental Models of HE (2009): Experimental models of hepatic encephalopathy: ISHEN guidelines. Liver Int., 29, 783-788.
    • (2009) Liver Int. , vol.29 , pp. 783-788
    • Butterworth, R.F.1    Norenberg, M.D.2    Felipo, V.3    Ferenci, P.4    Albrecht, J.5    Blei, A.T.6
  • 6
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: Recent developments and future needs
    • Cryan, J.F., Markou, A. and Lucki, I. (2002): Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol. Sci., 23, 238-245.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 8
    • 34247574175 scopus 로고    scopus 로고
    • The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
    • Dere, E., Huston, J.P. and De Souza Silva, M.A. (2007): The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci. Biobehav. Rev., 31, 673-704.
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 673-704
    • Dere, E.1    Huston, J.P.2    De Souza Silva, M.A.3
  • 9
    • 0029081299 scopus 로고
    • Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
    • Detke, M.J., Rickels, M. and Lucki, I. (1995): Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology (Berl), 121, 66-72.
    • (1995) Psychopharmacology (Berl) , vol.121 , pp. 66-72
    • Detke, M.J.1    Rickels, M.2    Lucki, I.3
  • 11
    • 0023691166 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data
    • Ennaceur, A. and Delacour, J. (1988): A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. Behav. Brain Res., 31, 47-59.
    • (1988) Behav. Brain Res. , vol.31 , pp. 47-59
    • Ennaceur, A.1    Delacour, J.2
  • 13
    • 0036191173 scopus 로고    scopus 로고
    • Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998
    • Ferenci, P., Lockwood, A., Mullen, K., Tarter, R., Weissenborn, K. and Blei, A.T. (2002): Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology, 35, 716-721.
    • (2002) Hepatology , vol.35 , pp. 716-721
    • Ferenci, P.1    Lockwood, A.2    Mullen, K.3    Tarter, R.4    Weissenborn, K.5    Blei, A.T.6
  • 16
    • 59949104431 scopus 로고    scopus 로고
    • Efficacy of urine bile acid as a non-invasive indicator of liver damage in rats
    • Kawai, H., Kudo, N., Kawashima, Y. and Mitsumoto, A. (2009): Efficacy of urine bile acid as a non-invasive indicator of liver damage in rats. J. Toxicol. Sci., 34, 27-38.
    • (2009) J. Toxicol. Sci. , vol.34 , pp. 27-38
    • Kawai, H.1    Kudo, N.2    Kawashima, Y.3    Mitsumoto, A.4
  • 17
    • 3042561627 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism
    • King, M.V., Sleight, A.J., Woolley, M.L., Topham, I.A., Marsden, C.A. and Fone, K.C.F. (2004): 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism. Neuropharmacology, 47, 195-204.
    • (2004) Neuropharmacology , vol.47 , pp. 195-204
    • King, M.V.1    Sleight, A.J.2    Woolley, M.L.3    Topham, I.A.4    Marsden, C.A.5    Fone, K.C.F.6
  • 18
    • 5444260564 scopus 로고    scopus 로고
    • Serotonin Brain Circuits with a Focus on Hepatic Encephalopathy
    • Lozeva-Thomas, V. (2004): Serotonin Brain Circuits with a Focus on Hepatic Encephalopathy. Metab. Brain Dis., 19, 413-420.
    • (2004) Metab. Brain Dis. , vol.19 , pp. 413-420
    • Lozeva-Thomas, V.1
  • 21
    • 52949132592 scopus 로고    scopus 로고
    • Working memory impairment and reduced hippocampal and prefrontal cortex c-Fos expression in a rat model of cirrhosis
    • Méndez, M., Méndez-López, M., López, L., Aller, M. Á., Árias, J. and Árias, J.L. (2008b): Working memory impairment and reduced hippocampal and prefrontal cortex c-Fos expression in a rat model of cirrhosis. Physiol. Behav., 95, 302-307.
    • (2008) Physiol. Behav. , vol.95 , pp. 302-307
    • Méndez, M.1    Méndez-López, M.2    López, L.3    Aller, M.A.4    Árias, J.5    Árias, J.L.6
  • 23
    • 79952008643 scopus 로고    scopus 로고
    • Acetylcholinesterase activity in an experimental rat model of Type C hepatic encephalopathy
    • Méndez, M., Méndez-López, M., López, L., Aller, M. Á., Árias, J. and Árias, J.L. (2011): Acetylcholinesterase activity in an experimental rat model of Type C hepatic encephalopathy. Acta Histochem., 113, 358-362.
    • (2011) Acta Histochem. , vol.113 , pp. 358-362
    • Méndez, M.1    Méndez-López, M.2    López, L.3    Aller, M.A.4    Árias, J.5    Árias, J.L.6
  • 24
    • 0026483309 scopus 로고
    • The effect of oral-administered lactulose on colonic nitrogen metabolism and excretion
    • Mortensen, P.B. (1992): The effect of oral-administered lactulose on colonic nitrogen metabolism and excretion. Hepatology, 16, 1350-1356.
    • (1992) Hepatology , vol.16 , pp. 1350-1356
    • Mortensen, P.B.1
  • 26
    • 0023751476 scopus 로고
    • Thioacetamide-induced cirrhosis-like liver lesions in rats--usefulness and reliability of this animal model
    • Müller, A., Machnik, F., Zimmermann, T. and Schubert, H. (1988): Thioacetamide-induced cirrhosis-like liver lesions in rats--usefulness and reliability of this animal model. Exp. Pathol., 34, 229-236.
    • (1988) Exp. Pathol. , vol.34 , pp. 229-236
    • Müller, A.1    Machnik, F.2    Zimmermann, T.3    Schubert, H.4
  • 28
    • 0028892020 scopus 로고
    • Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: A new model of schizophrenia
    • Noda, Y., Yamada, K., Furukawa, H. and Nabeshima, T. (1995): Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: a new model of schizophrenia. Br. J. Pharmacol., 116, 2531-2537.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2531-2537
    • Noda, Y.1    Yamada, K.2    Furukawa, H.3    Nabeshima, T.4
  • 29
    • 0031003482 scopus 로고    scopus 로고
    • Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice
    • Noda, Y., Mamiya, T., Furukawa, H. and Nabeshima, T. (1997): Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice. Eur. J. Pharmacol., 324, 135-140.
    • (1997) Eur. J. Pharmacol. , vol.324 , pp. 135-140
    • Noda, Y.1    Mamiya, T.2    Furukawa, H.3    Nabeshima, T.4
  • 30
    • 24044450242 scopus 로고    scopus 로고
    • The 5-HT2C receptor antagonist RO 60-0491 counteracts rats' retention deficits in a recognition memory task
    • Pitsikas, N. and Sakellaridis, N. (2005): The 5-HT2C receptor antagonist RO 60-0491 counteracts rats' retention deficits in a recognition memory task. Brain Res., 1054, 200-202.
    • (2005) Brain Res. , vol.1054 , pp. 200-202
    • Pitsikas, N.1    Sakellaridis, N.2
  • 31
    • 0018268297 scopus 로고
    • Behavioural despair in rats: A new model sensitive to antidepressant treatments
    • Porsolt, R.D., Anton, G., Blavet, N. and Jalfre, M. (1978): Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol., 47, 379-391.
    • (1978) Eur. J. Pharmacol. , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 32
    • 33947392621 scopus 로고    scopus 로고
    • Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy
    • Prasad, S., Dhiman, R.K., Duseja, A., Chawla, Y.K., Sharma, A. and Agarwal, R. (2007): Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy. Hepatology, 45, 549-559.
    • (2007) Hepatology , vol.45 , pp. 549-559
    • Prasad, S.1    Dhiman, R.K.2    Duseja, A.3    Chawla, Y.K.4    Sharma, A.5    Agarwal, R.6
  • 33
    • 0036389260 scopus 로고    scopus 로고
    • A novel model of acetaminophen-induced acute hepatic failure in rabbits
    • Rahman, T.M., Selden, A.C. and Hodgson H.J.F. (2002): A novel model of acetaminophen-induced acute hepatic failure in rabbits. J. Surg. Res., 106, 264-272.
    • (2002) J. Surg. Res. , vol.106 , pp. 264-272
    • Rahman, T.M.1    Selden, A.C.2    Hodgson, H.J.F.3
  • 35
    • 0033977472 scopus 로고    scopus 로고
    • The decrease in total collagen fibers in the liver by hepatocyte growth factor after formation of cirrhosis induced by thioacetamide
    • Sato, M., Kakubari, M., Kawamura, M., Sugimoto, J., Matsumoto, K. and Ishii, T. (2000): The decrease in total collagen fibers in the liver by hepatocyte growth factor after formation of cirrhosis induced by thioacetamide. Biochem. Pharmacol., 59, 681-690.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 681-690
    • Sato, M.1    Kakubari, M.2    Kawamura, M.3    Sugimoto, J.4    Matsumoto, K.5    Ishii, T.6
  • 36
    • 33646677275 scopus 로고    scopus 로고
    • Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: Correlation with AMPA receptor subunit expression in rat hippocampus
    • Schiapparelli, L., Simon, A.M., Del Rio, J. and Frechilla, D. (2006): Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: correlation with AMPA receptor subunit expression in rat hippocampus. Neuropharmacology, 50, 897-907.
    • (2006) Neuropharmacology , vol.50 , pp. 897-907
    • Schiapparelli, L.1    Simon, A.M.2    Del Rio, J.3    Frechilla, D.4
  • 38
    • 0029911117 scopus 로고    scopus 로고
    • A low-protein diet ameliorates disrupted diurnal locomotor activity in rats after portacaval anastomosis
    • Steindl, P.E., Coy, D.L., Finn, B., Zee, P.C. and Blei, A.T. (1996): A low-protein diet ameliorates disrupted diurnal locomotor activity in rats after portacaval anastomosis. Am. J. Physiol., 271, G555-560.
    • (1996) Am. J. Physiol. , vol.271
    • Steindl, P.E.1    Coy, D.L.2    Finn, B.3    Zee, P.C.4    Blei, A.T.5
  • 40
    • 0023620799 scopus 로고
    • Blood ammonia levels and hepatic encephalopathy induced by CCl4 in rats
    • Yamamoto, H. and Sugihara, N. (1987): Blood ammonia levels and hepatic encephalopathy induced by CCl4 in rats. Toxicol. Appl. Pharmacol., 91, 461-468.
    • (1987) Toxicol. Appl. Pharmacol. , vol.91 , pp. 461-468
    • Yamamoto, H.1    Sugihara, N.2
  • 41
    • 0030012377 scopus 로고    scopus 로고
    • Modulation of hepatic encephalopathy in rats with thioacetamide-induced acute liver failure by serotonin antagonists
    • Yurdaydin, C., Herneth, A.M., Puspok, A., Steindl, P., Singer, E. and Ferenci, P. (1996). Modulation of hepatic encephalopathy in rats with thioacetamide-induced acute liver failure by serotonin antagonists. Eur. J. Gastroenterol. Hepatol., 8, 667-671.
    • (1996) Eur. J. Gastroenterol. Hepatol. , vol.8 , pp. 667-671
    • Yurdaydin, C.1    Herneth, A.M.2    Puspok, A.3    Steindl, P.4    Singer, E.5    Ferenci, P.6
  • 42
    • 0024502916 scopus 로고
    • Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission
    • Zimmermann, C., Ferenci, P., Pifl, C., Yurdaydin, C., Ebner, J., Lassmann, H., Roth, E. and Hortnagl, H. (1989). Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: characterization of an improved model and study of amino acid-ergic neurotransmission. Hepatology, 9, 594-601.
    • (1989) Hepatology , vol.9 , pp. 594-601
    • Zimmermann, C.1    Ferenci, P.2    Pifl, C.3    Yurdaydin, C.4    Ebner, J.5    Lassmann, H.6    Roth, E.7    Hortnagl, H.8


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