메뉴 건너뛰기




Volumn 106, Issue 2, 2002, Pages 264-272

A novel model of acetaminophen-induced acute hepatic failure in rabbits

Author keywords

Acetaminophen; Fulminant; Hepatic; Liver; Methylcholanthrene; Phenobarbitone

Indexed keywords

3 METHYLCHOLANTHRENE; ASPARTATE AMINOTRANSFERASE; BUTHIONINE SULFOXIMINE; CREATININE; CYTOCHROME P450; ENZYME INHIBITOR; GLUTATHIONE; GLUTATHIONE SYNTHASE; LACTIC ACID; PARACETAMOL; PHENOBARBITAL;

EID: 0036389260     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2002.6476     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 0025907763 scopus 로고
    • Animal models of fulminant hepatic failure
    • Terblanche, J., and Hickman, R. Animal models of fulminant hepatic failure. Dig. Dis. Sci. 36: 770, 1991.
    • (1991) Dig. Dis. Sci. , vol.36 , pp. 770
    • Terblanche, J.1    Hickman, R.2
  • 2
    • 0023877502 scopus 로고
    • Species variation in toxication and detoxication of acetaminophen in vivo: A comparative study of biliary and urinary excretion of acetaminophen metabolites
    • Gregus, Z., Madhu, C., and Klaassen, C. D. Species variation in toxication and detoxication of acetaminophen in vivo: A comparative study of biliary and urinary excretion of acetaminophen metabolites. J. Pharmacol. Exp. Ther. 244: 91, 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 91
    • Gregus, Z.1    Madhu, C.2    Klaassen, C.D.3
  • 3
    • 0021242998 scopus 로고
    • Hepatotoxicity of acetaminophen in neonatal and young rats. I. Age-related changes in susceptibility
    • Green, M. D., Shires, T. K., and Fischer, L. J. Hepatotoxicity of acetaminophen in neonatal and young rats. I. Age-related changes in susceptibility. Toxicol. Appl. Pharmacol. 74: 116, 1984.
    • (1984) Toxicol. Appl. Pharmacol. , vol.74 , pp. 116
    • Green, M.D.1    Shires, T.K.2    Fischer, L.J.3
  • 4
    • 0021238226 scopus 로고
    • Hepatotoxicity of acetaminophen in neonatal and young rats. II. Metabolic aspects
    • Green, M. D., and Fischer, L. J. Hepatotoxicity of acetaminophen in neonatal and young rats. II. Metabolic aspects. Toxicol. Appl. Pharmacol. 74: 125, 1984.
    • (1984) Toxicol. Appl. Pharmacol. , vol.74 , pp. 125
    • Green, M.D.1    Fischer, L.J.2
  • 5
    • 0021177280 scopus 로고
    • Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species
    • Green, C. E., Dabbs, J. E., and Tyson, C. A. Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species. Toxicol. Appl. Pharmacol. 76: 139, 1984.
    • (1984) Toxicol. Appl. Pharmacol. , vol.76 , pp. 139
    • Green, C.E.1    Dabbs, J.E.2    Tyson, C.A.3
  • 6
    • 0013884903 scopus 로고
    • Liver necrosis from paracetamol
    • Boyd, E. M., and Bereczky, G. M. Liver necrosis from paracetamol. Br. J. Pharmacol. 26: 606, 1966.
    • (1966) Br. J. Pharmacol. , vol.26 , pp. 606
    • Boyd, E.M.1    Bereczky, G.M.2
  • 7
    • 0014257340 scopus 로고
    • The chronic oral toxicity of paracetamol at the range of the LD50 (100 days) in albino rats
    • Boyd, E. M., and Hogan, S. E. The chronic oral toxicity of paracetamol at the range of the LD50 (100 days) in albino rats. Can. J. Physiol. Pharmacol. 46: 239, 1968.
    • (1968) Can. J. Physiol. Pharmacol. , vol.46 , pp. 239
    • Boyd, E.M.1    Hogan, S.E.2
  • 8
    • 0016356278 scopus 로고
    • Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen
    • Jollow, D. J., Thorgeirsson, S. S., Potter, W. Z., et al. Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology 12: 251, 1974.
    • (1974) Pharmacology , vol.12 , pp. 251
    • Jollow, D.J.1    Thorgeirsson, S.S.2    Potter, W.Z.3
  • 9
    • 0019209787 scopus 로고
    • Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine
    • Corcoran, G. B., Mitchell, J. R., and Horning, E. C. Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine. Mol. Pharmacol. 18: 536, 1980.
    • (1980) Mol. Pharmacol. , vol.18 , pp. 536
    • Corcoran, G.B.1    Mitchell, J.R.2    Horning, E.C.3
  • 10
    • 0019775423 scopus 로고
    • Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney
    • Mohandas, J., Duggin, G. G., Tiller, D. J. Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney. Toxicol. Appl. Pharmacol. 61: 252, 1981.
    • (1981) Toxicol. Appl. Pharmacol. , vol.61 , pp. 252
    • Mohandas, J.1    Duggin, G.G.2    Tiller, D.J.3
  • 11
    • 0020633304 scopus 로고
    • Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen
    • Morgan, E. T., Koop, D. R., and Coon, M. J. Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen. Biochem. Biophys. Res. Commun. 112: 8, 1983.
    • (1983) Biochem. Biophys. Res. Commun. , vol.112 , pp. 8
    • Morgan, E.T.1    Koop, D.R.2    Coon, M.J.3
  • 12
    • 0017347113 scopus 로고
    • Experimental hepatic injury: The sequential changes in drug metabolizing enzyme activities after administration of acetaminophen
    • Willson, R. A., and Hart, F. E. Experimental hepatic injury: The sequential changes in drug metabolizing enzyme activities after administration of acetaminophen. Res. Commun. Chem. Pathol. Pharmacol. 16: 59, 1977.
    • (1977) Res. Commun. Chem. Pathol. Pharmacol. , vol.16 , pp. 59
    • Willson, R.A.1    Hart, F.E.2
  • 13
    • 0021923797 scopus 로고
    • Phenobarbital induction does not potentiate hepatotoxicity but accelerates liver cell necrosis from acetaminophen overdose in the rat
    • Poulsen, H. E., Lerche, A., and Pedersen, N. T. Phenobarbital induction does not potentiate hepatotoxicity but accelerates liver cell necrosis from acetaminophen overdose in the rat. Pharmacology 30: 100, 1985.
    • (1985) Pharmacology , vol.30 , pp. 100
    • Poulsen, H.E.1    Lerche, A.2    Pedersen, N.T.3
  • 14
    • 0023145347 scopus 로고
    • A novel mechanism for the enhancement of acetaminophen hepatotoxicity by phenobarbital
    • Douidar, S. M., and Ahmed, A. E. A novel mechanism for the enhancement of acetaminophen hepatotoxicity by phenobarbital. J. Pharmacol. Exp. Ther. 240: 578, 1987.
    • (1987) J. Pharmacol. Exp. Ther. , vol.240 , pp. 578
    • Douidar, S.M.1    Ahmed, A.E.2
  • 15
    • 0026644749 scopus 로고
    • Differential oxidase activity of hepatic and pulmonary microsomal cytochrome P-450 isozymes after treatment with cytochrome P-450 inducers
    • Sakai, H, Park, S. S., and Kikkawa, Y. Differential oxidase activity of hepatic and pulmonary microsomal cytochrome P-450 isozymes after treatment with cytochrome P-450 inducers. Biochem. Biophys. Res. Commun. 187: 1262, 1992.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 1262
    • Sakai, H.1    Park, S.S.2    Kikkawa, Y.3
  • 16
    • 0027292438 scopus 로고
    • Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes
    • Nishibe, Y., and Hirata, M. Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes. Xenobiotica 23: 681, 1993.
    • (1993) Xenobiotica , vol.23 , pp. 681
    • Nishibe, Y.1    Hirata, M.2
  • 17
    • 0029077911 scopus 로고
    • Induction of cytochrome P-450 isoenzymes in cultured monkey hepatocytes
    • Nishibe, Y., and Hirata, M. Induction of cytochrome P-450 isoenzymes in cultured monkey hepatocytes. Int. J. Biochem. Cell Biol. 27: 279, 1995.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 279
    • Nishibe, Y.1    Hirata, M.2
  • 18
    • 0020701603 scopus 로고
    • Species variation in the metabolic activation of paracetamol to toxic intermediates: Role of cytochromes p-450 and p-448
    • Ioannides, C., Steele, C. M., and Parke, D. V. Species variation in the metabolic activation of paracetamol to toxic intermediates: Role of cytochromes p-450 and p-448. Toxicol. Lett. 16: 55, 1983.
    • (1983) Toxicol. Lett. , vol.16 , pp. 55
    • Ioannides, C.1    Steele, C.M.2    Parke, D.V.3
  • 19
    • 12644302207 scopus 로고    scopus 로고
    • Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells
    • Lerche, C., Fautrel, A., Corcos, I., et al. Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells. Eur. J. Biochem. 244: 98, 1997.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 98
    • Lerche, C.1    Fautrel, A.2    Corcos, I.3
  • 20
    • 0032499419 scopus 로고    scopus 로고
    • Induction time course of cytochromes P450 by phenobarbital and 3-methylcholanthrene pretreatment in liver microsomes of Alligator mississippiensis
    • Ertl, R. P., Stegeman, J. J., and Winston, G. W. Induction time course of cytochromes P450 by phenobarbital and 3-methylcholanthrene pretreatment in liver microsomes of Alligator mississippiensis. Biochem. Pharmacol. 55: 1513, 1998.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1513
    • Ertl, R.P.1    Stegeman, J.J.2    Winston, G.W.3
  • 21
    • 0017124905 scopus 로고
    • Effect of 3-methylcholanthrene pretreatment on the bioavailability of phenacetin in the rat
    • Welch, R. M., Hughes, C. R., and Deangelis, R. L. Effect of 3-methylcholanthrene pretreatment on the bioavailability of phenacetin in the rat. Drug Metab. Dispos. 4: 402, 1976.
    • (1976) Drug Metab. Dispos. , vol.4 , pp. 402
    • Welch, R.M.1    Hughes, C.R.2    Deangelis, R.L.3
  • 22
    • 0026008585 scopus 로고
    • Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies
    • Liu, G., Gelboin, H. V., and Myers, M. J. Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies. Arch. Biochem. Biophys. 284: 400, 1991.
    • (1991) Arch. Biochem. Biophys. , vol.284 , pp. 400
    • Liu, G.1    Gelboin, H.V.2    Myers, M.J.3
  • 23
    • 0023234293 scopus 로고
    • In vivo and in vitro hepatotoxicity and metabolism of acetaminophen in Syrian hamsters
    • Lupo, S., Yodis, L. A., Rush, G. F., et al. In vivo and in vitro hepatotoxicity and metabolism of acetaminophen in Syrian hamsters. Toxicology 44: 229, 1987.
    • (1987) Toxicology , vol.44 , pp. 229
    • Lupo, S.1    Yodis, L.A.2    Rush, G.F.3
  • 24
    • 0020444895 scopus 로고
    • Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis
    • Griffith, O. W. Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis. J. Biol. Chem. 257: 13704, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13704
    • Griffith, O.W.1
  • 25
    • 0026595997 scopus 로고
    • An improved model of acetaminophen-induced fulminant hepatic failure in dogs
    • Kelly, J. H., Koussayer, T., Chong, M. G., and Sussman, N. L. An improved model of acetaminophen-induced fulminant hepatic failure in dogs. Hepatology 15: 329, 1992.
    • (1992) Hepatology , vol.15 , pp. 329
    • Kelly, J.H.1    Koussayer, T.2    Chong, M.G.3    Sussman, N.L.4
  • 26
    • 0016826786 scopus 로고
    • A dog model of fulminant hepatic failure produced by paracetamol administration
    • Gazzard, B. G., Hughes, R. D., Williams, R., et al. A dog model of fulminant hepatic failure produced by paracetamol administration. Br. J. Exp. Pathol. 56: 408, 1975.
    • (1975) Br. J. Exp. Pathol. , vol.56 , pp. 408
    • Gazzard, B.G.1    Hughes, R.D.2    Williams, R.3
  • 27
    • 0017184970 scopus 로고
    • An animal model of fulminant hepatic failure: A feasibility study
    • Miller, D. J., Hickman, R., Fratter, R., et al. An animal model of fulminant hepatic failure: a feasibility study. Gastroenterology 71: 109, 1976.
    • (1976) Gastroenterology , vol.71 , pp. 109
    • Miller, D.J.1    Hickman, R.2    Fratter, R.3
  • 29
    • 0023768334 scopus 로고
    • Acetaminophen-induced acute hepatic failure in pigs: Controversical results to other animal models
    • Henne Bruns, D., Artwohl, J., Broelsch, C., et al. Acetaminophen-induced acute hepatic failure in pigs: Controversical results to other animal models. Res. Exp. Med. Berl. 188: 463, 1988.
    • (1988) Res. Exp. Med. Berl. , vol.188 , pp. 463
    • Henne Bruns, D.1    Artwohl, J.2    Broelsch, C.3
  • 30
    • 0019833350 scopus 로고
    • Regional differences in peroxidatic activation of paracetamol (acetaminophen) mediated by cytochrome P450 and prostaglandin endoperoxide synthetase in rabbit kidney
    • Mohandas, J., Duggin, G. G., Horvath, J. S., et al. Regional differences in peroxidatic activation of paracetamol (acetaminophen) mediated by cytochrome P450 and prostaglandin endoperoxide synthetase in rabbit kidney. Res. Commun. Chem. Pathol. Pharmacol. 34: 69, 1981.
    • (1981) Res. Commun. Chem. Pathol. Pharmacol. , vol.34 , pp. 69
    • Mohandas, J.1    Duggin, G.G.2    Horvath, J.S.3
  • 31
    • 0024502916 scopus 로고
    • Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission
    • Zimmermann, C., Ferenci, P., Pifl, C., et al. Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission. Hepatology 9: 594, 1989.
    • (1989) Hepatology , vol.9 , pp. 594
    • Zimmermann, C.1    Ferenci, P.2    Pifl, C.3
  • 32
    • 0020629369 scopus 로고
    • Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure
    • Gstraunthaler, G., Pfaller, W., and Kotanko, P: Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure. Biochem. Pharmacol. 32: 2969, 1983.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 2969
    • Gstraunthaler, G.1    Pfaller, W.2    Kotanko, P.3
  • 33
    • 0026458615 scopus 로고
    • Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen
    • Szymanska, J. A., Swietlicka, E. A., Piotrowski, J. K., et al. Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen. J. Appl. Toxicol. 12: 415, 1992.
    • (1992) J. Appl. Toxicol. , vol.12 , pp. 415
    • Szymanska, J.A.1    Swietlicka, E.A.2    Piotrowski, J.K.3
  • 34
    • 0024499767 scopus 로고
    • A dog model for acetaminophen-induced fulminant hepatic failure
    • Francavilla, A., Makowka, L., Polimeno, L., et al. A dog model for acetaminophen-induced fulminant hepatic failure. Gastroenterology 96: 470, 1989.
    • (1989) Gastroenterology , vol.96 , pp. 470
    • Francavilla, A.1    Makowka, L.2    Polimeno, L.3
  • 35
    • 0031890184 scopus 로고    scopus 로고
    • Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat
    • Gardner, C. R., Heck, D. E., Yang, C. S., et al. Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat. Hepatology 27: 748, 1998.
    • (1998) Hepatology , vol.27 , pp. 748
    • Gardner, C.R.1    Heck, D.E.2    Yang, C.S.3
  • 36
    • 0021154323 scopus 로고
    • Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy
    • Mohandas, J., Marshall, J. J., Duggin, G. G., et al. Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy. Biochem. Pharmacol. 33: 1801, 1984.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 1801
    • Mohandas, J.1    Marshall, J.J.2    Duggin, G.G.3
  • 37
    • 0023893602 scopus 로고
    • A histopathological study of analgesic hepatotoxicity in rabbit
    • Qamar, M. A., and Alam, S. M. A histopathological study of analgesic hepatotoxicity in rabbit. J. Pak. Med. Assoc. 38: 41, 1988.
    • (1988) J. Pak. Med. Assoc. , vol.38 , pp. 41
    • Qamar, M.A.1    Alam, S.M.2
  • 38
    • 0015754446 scopus 로고
    • Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
    • Jollow, D. J., Mitchell, J. R., Potter, W. Z., et al. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J. Pharmacol. Exp. Ther. 187: 195, 1973.
    • (1973) J. Pharmacol. Exp. Ther. , vol.187 , pp. 195
    • Jollow, D.J.1    Mitchell, J.R.2    Potter, W.Z.3
  • 39
    • 0031713986 scopus 로고    scopus 로고
    • Disorders of the mitochondria
    • Treem, W. R., and Sokol, R. J.: Disorders of the mitochondria. Semin. Liver Dis. 18: 237, 1998.
    • (1998) Semin. Liver Dis. , vol.18 , pp. 237
    • Treem, W.R.1    Sokol, R.J.2
  • 40
    • 0028939262 scopus 로고
    • An anesthetized model of lethal canine galactosamine fulminant hepatic failure
    • Sielaff, T. D., Hu, M. Y., Rollins, M. D., et al. An anesthetized model of lethal canine galactosamine fulminant hepatic failure. Hepatology 21: 796, 1995.
    • (1995) Hepatology , vol.21 , pp. 796
    • Sielaff, T.D.1    Hu, M.Y.2    Rollins, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.