-
1
-
-
0025907763
-
Animal models of fulminant hepatic failure
-
Terblanche, J., and Hickman, R. Animal models of fulminant hepatic failure. Dig. Dis. Sci. 36: 770, 1991.
-
(1991)
Dig. Dis. Sci.
, vol.36
, pp. 770
-
-
Terblanche, J.1
Hickman, R.2
-
2
-
-
0023877502
-
Species variation in toxication and detoxication of acetaminophen in vivo: A comparative study of biliary and urinary excretion of acetaminophen metabolites
-
Gregus, Z., Madhu, C., and Klaassen, C. D. Species variation in toxication and detoxication of acetaminophen in vivo: A comparative study of biliary and urinary excretion of acetaminophen metabolites. J. Pharmacol. Exp. Ther. 244: 91, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 91
-
-
Gregus, Z.1
Madhu, C.2
Klaassen, C.D.3
-
3
-
-
0021242998
-
Hepatotoxicity of acetaminophen in neonatal and young rats. I. Age-related changes in susceptibility
-
Green, M. D., Shires, T. K., and Fischer, L. J. Hepatotoxicity of acetaminophen in neonatal and young rats. I. Age-related changes in susceptibility. Toxicol. Appl. Pharmacol. 74: 116, 1984.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.74
, pp. 116
-
-
Green, M.D.1
Shires, T.K.2
Fischer, L.J.3
-
4
-
-
0021238226
-
Hepatotoxicity of acetaminophen in neonatal and young rats. II. Metabolic aspects
-
Green, M. D., and Fischer, L. J. Hepatotoxicity of acetaminophen in neonatal and young rats. II. Metabolic aspects. Toxicol. Appl. Pharmacol. 74: 125, 1984.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.74
, pp. 125
-
-
Green, M.D.1
Fischer, L.J.2
-
5
-
-
0021177280
-
Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species
-
Green, C. E., Dabbs, J. E., and Tyson, C. A. Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species. Toxicol. Appl. Pharmacol. 76: 139, 1984.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.76
, pp. 139
-
-
Green, C.E.1
Dabbs, J.E.2
Tyson, C.A.3
-
7
-
-
0014257340
-
The chronic oral toxicity of paracetamol at the range of the LD50 (100 days) in albino rats
-
Boyd, E. M., and Hogan, S. E. The chronic oral toxicity of paracetamol at the range of the LD50 (100 days) in albino rats. Can. J. Physiol. Pharmacol. 46: 239, 1968.
-
(1968)
Can. J. Physiol. Pharmacol.
, vol.46
, pp. 239
-
-
Boyd, E.M.1
Hogan, S.E.2
-
8
-
-
0016356278
-
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen
-
Jollow, D. J., Thorgeirsson, S. S., Potter, W. Z., et al. Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology 12: 251, 1974.
-
(1974)
Pharmacology
, vol.12
, pp. 251
-
-
Jollow, D.J.1
Thorgeirsson, S.S.2
Potter, W.Z.3
-
9
-
-
0019209787
-
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine
-
Corcoran, G. B., Mitchell, J. R., and Horning, E. C. Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine. Mol. Pharmacol. 18: 536, 1980.
-
(1980)
Mol. Pharmacol.
, vol.18
, pp. 536
-
-
Corcoran, G.B.1
Mitchell, J.R.2
Horning, E.C.3
-
10
-
-
0019775423
-
Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney
-
Mohandas, J., Duggin, G. G., Tiller, D. J. Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney. Toxicol. Appl. Pharmacol. 61: 252, 1981.
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.61
, pp. 252
-
-
Mohandas, J.1
Duggin, G.G.2
Tiller, D.J.3
-
11
-
-
0020633304
-
Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen
-
Morgan, E. T., Koop, D. R., and Coon, M. J. Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen. Biochem. Biophys. Res. Commun. 112: 8, 1983.
-
(1983)
Biochem. Biophys. Res. Commun.
, vol.112
, pp. 8
-
-
Morgan, E.T.1
Koop, D.R.2
Coon, M.J.3
-
12
-
-
0017347113
-
Experimental hepatic injury: The sequential changes in drug metabolizing enzyme activities after administration of acetaminophen
-
Willson, R. A., and Hart, F. E. Experimental hepatic injury: The sequential changes in drug metabolizing enzyme activities after administration of acetaminophen. Res. Commun. Chem. Pathol. Pharmacol. 16: 59, 1977.
-
(1977)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.16
, pp. 59
-
-
Willson, R.A.1
Hart, F.E.2
-
13
-
-
0021923797
-
Phenobarbital induction does not potentiate hepatotoxicity but accelerates liver cell necrosis from acetaminophen overdose in the rat
-
Poulsen, H. E., Lerche, A., and Pedersen, N. T. Phenobarbital induction does not potentiate hepatotoxicity but accelerates liver cell necrosis from acetaminophen overdose in the rat. Pharmacology 30: 100, 1985.
-
(1985)
Pharmacology
, vol.30
, pp. 100
-
-
Poulsen, H.E.1
Lerche, A.2
Pedersen, N.T.3
-
14
-
-
0023145347
-
A novel mechanism for the enhancement of acetaminophen hepatotoxicity by phenobarbital
-
Douidar, S. M., and Ahmed, A. E. A novel mechanism for the enhancement of acetaminophen hepatotoxicity by phenobarbital. J. Pharmacol. Exp. Ther. 240: 578, 1987.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.240
, pp. 578
-
-
Douidar, S.M.1
Ahmed, A.E.2
-
15
-
-
0026644749
-
Differential oxidase activity of hepatic and pulmonary microsomal cytochrome P-450 isozymes after treatment with cytochrome P-450 inducers
-
Sakai, H, Park, S. S., and Kikkawa, Y. Differential oxidase activity of hepatic and pulmonary microsomal cytochrome P-450 isozymes after treatment with cytochrome P-450 inducers. Biochem. Biophys. Res. Commun. 187: 1262, 1992.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 1262
-
-
Sakai, H.1
Park, S.S.2
Kikkawa, Y.3
-
16
-
-
0027292438
-
Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes
-
Nishibe, Y., and Hirata, M. Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes. Xenobiotica 23: 681, 1993.
-
(1993)
Xenobiotica
, vol.23
, pp. 681
-
-
Nishibe, Y.1
Hirata, M.2
-
17
-
-
0029077911
-
Induction of cytochrome P-450 isoenzymes in cultured monkey hepatocytes
-
Nishibe, Y., and Hirata, M. Induction of cytochrome P-450 isoenzymes in cultured monkey hepatocytes. Int. J. Biochem. Cell Biol. 27: 279, 1995.
-
(1995)
Int. J. Biochem. Cell Biol.
, vol.27
, pp. 279
-
-
Nishibe, Y.1
Hirata, M.2
-
18
-
-
0020701603
-
Species variation in the metabolic activation of paracetamol to toxic intermediates: Role of cytochromes p-450 and p-448
-
Ioannides, C., Steele, C. M., and Parke, D. V. Species variation in the metabolic activation of paracetamol to toxic intermediates: Role of cytochromes p-450 and p-448. Toxicol. Lett. 16: 55, 1983.
-
(1983)
Toxicol. Lett.
, vol.16
, pp. 55
-
-
Ioannides, C.1
Steele, C.M.2
Parke, D.V.3
-
19
-
-
12644302207
-
Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells
-
Lerche, C., Fautrel, A., Corcos, I., et al. Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells. Eur. J. Biochem. 244: 98, 1997.
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 98
-
-
Lerche, C.1
Fautrel, A.2
Corcos, I.3
-
20
-
-
0032499419
-
Induction time course of cytochromes P450 by phenobarbital and 3-methylcholanthrene pretreatment in liver microsomes of Alligator mississippiensis
-
Ertl, R. P., Stegeman, J. J., and Winston, G. W. Induction time course of cytochromes P450 by phenobarbital and 3-methylcholanthrene pretreatment in liver microsomes of Alligator mississippiensis. Biochem. Pharmacol. 55: 1513, 1998.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 1513
-
-
Ertl, R.P.1
Stegeman, J.J.2
Winston, G.W.3
-
21
-
-
0017124905
-
Effect of 3-methylcholanthrene pretreatment on the bioavailability of phenacetin in the rat
-
Welch, R. M., Hughes, C. R., and Deangelis, R. L. Effect of 3-methylcholanthrene pretreatment on the bioavailability of phenacetin in the rat. Drug Metab. Dispos. 4: 402, 1976.
-
(1976)
Drug Metab. Dispos.
, vol.4
, pp. 402
-
-
Welch, R.M.1
Hughes, C.R.2
Deangelis, R.L.3
-
22
-
-
0026008585
-
Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies
-
Liu, G., Gelboin, H. V., and Myers, M. J. Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies. Arch. Biochem. Biophys. 284: 400, 1991.
-
(1991)
Arch. Biochem. Biophys.
, vol.284
, pp. 400
-
-
Liu, G.1
Gelboin, H.V.2
Myers, M.J.3
-
23
-
-
0023234293
-
In vivo and in vitro hepatotoxicity and metabolism of acetaminophen in Syrian hamsters
-
Lupo, S., Yodis, L. A., Rush, G. F., et al. In vivo and in vitro hepatotoxicity and metabolism of acetaminophen in Syrian hamsters. Toxicology 44: 229, 1987.
-
(1987)
Toxicology
, vol.44
, pp. 229
-
-
Lupo, S.1
Yodis, L.A.2
Rush, G.F.3
-
24
-
-
0020444895
-
Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis
-
Griffith, O. W. Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis. J. Biol. Chem. 257: 13704, 1982.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13704
-
-
Griffith, O.W.1
-
25
-
-
0026595997
-
An improved model of acetaminophen-induced fulminant hepatic failure in dogs
-
Kelly, J. H., Koussayer, T., Chong, M. G., and Sussman, N. L. An improved model of acetaminophen-induced fulminant hepatic failure in dogs. Hepatology 15: 329, 1992.
-
(1992)
Hepatology
, vol.15
, pp. 329
-
-
Kelly, J.H.1
Koussayer, T.2
Chong, M.G.3
Sussman, N.L.4
-
26
-
-
0016826786
-
A dog model of fulminant hepatic failure produced by paracetamol administration
-
Gazzard, B. G., Hughes, R. D., Williams, R., et al. A dog model of fulminant hepatic failure produced by paracetamol administration. Br. J. Exp. Pathol. 56: 408, 1975.
-
(1975)
Br. J. Exp. Pathol.
, vol.56
, pp. 408
-
-
Gazzard, B.G.1
Hughes, R.D.2
Williams, R.3
-
27
-
-
0017184970
-
An animal model of fulminant hepatic failure: A feasibility study
-
Miller, D. J., Hickman, R., Fratter, R., et al. An animal model of fulminant hepatic failure: a feasibility study. Gastroenterology 71: 109, 1976.
-
(1976)
Gastroenterology
, vol.71
, pp. 109
-
-
Miller, D.J.1
Hickman, R.2
Fratter, R.3
-
28
-
-
0010729702
-
(Paracetamol poisoning in a swine model) paracetamol-intoxikation im Schweinemodell
-
Henne Bruns, D., Artwohl, J., Dziwisch, L., et al. (Paracetamol poisoning in a swine model) Paracetamol-Intoxikation im Schweinemodell. Z. Exp. Chir. Transplant. Kunstliche. Organe. 21: 255, 1988.
-
(1988)
Z. Exp. Chir. Transplant. Kunstliche. Organe.
, vol.21
, pp. 255
-
-
Henne Bruns, D.1
Artwohl, J.2
Dziwisch, L.3
-
29
-
-
0023768334
-
Acetaminophen-induced acute hepatic failure in pigs: Controversical results to other animal models
-
Henne Bruns, D., Artwohl, J., Broelsch, C., et al. Acetaminophen-induced acute hepatic failure in pigs: Controversical results to other animal models. Res. Exp. Med. Berl. 188: 463, 1988.
-
(1988)
Res. Exp. Med. Berl.
, vol.188
, pp. 463
-
-
Henne Bruns, D.1
Artwohl, J.2
Broelsch, C.3
-
30
-
-
0019833350
-
Regional differences in peroxidatic activation of paracetamol (acetaminophen) mediated by cytochrome P450 and prostaglandin endoperoxide synthetase in rabbit kidney
-
Mohandas, J., Duggin, G. G., Horvath, J. S., et al. Regional differences in peroxidatic activation of paracetamol (acetaminophen) mediated by cytochrome P450 and prostaglandin endoperoxide synthetase in rabbit kidney. Res. Commun. Chem. Pathol. Pharmacol. 34: 69, 1981.
-
(1981)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.34
, pp. 69
-
-
Mohandas, J.1
Duggin, G.G.2
Horvath, J.S.3
-
31
-
-
0024502916
-
Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission
-
Zimmermann, C., Ferenci, P., Pifl, C., et al. Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission. Hepatology 9: 594, 1989.
-
(1989)
Hepatology
, vol.9
, pp. 594
-
-
Zimmermann, C.1
Ferenci, P.2
Pifl, C.3
-
32
-
-
0020629369
-
Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure
-
Gstraunthaler, G., Pfaller, W., and Kotanko, P: Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure. Biochem. Pharmacol. 32: 2969, 1983.
-
(1983)
Biochem. Pharmacol.
, vol.32
, pp. 2969
-
-
Gstraunthaler, G.1
Pfaller, W.2
Kotanko, P.3
-
33
-
-
0026458615
-
Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen
-
Szymanska, J. A., Swietlicka, E. A., Piotrowski, J. K., et al. Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen. J. Appl. Toxicol. 12: 415, 1992.
-
(1992)
J. Appl. Toxicol.
, vol.12
, pp. 415
-
-
Szymanska, J.A.1
Swietlicka, E.A.2
Piotrowski, J.K.3
-
34
-
-
0024499767
-
A dog model for acetaminophen-induced fulminant hepatic failure
-
Francavilla, A., Makowka, L., Polimeno, L., et al. A dog model for acetaminophen-induced fulminant hepatic failure. Gastroenterology 96: 470, 1989.
-
(1989)
Gastroenterology
, vol.96
, pp. 470
-
-
Francavilla, A.1
Makowka, L.2
Polimeno, L.3
-
35
-
-
0031890184
-
Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat
-
Gardner, C. R., Heck, D. E., Yang, C. S., et al. Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat. Hepatology 27: 748, 1998.
-
(1998)
Hepatology
, vol.27
, pp. 748
-
-
Gardner, C.R.1
Heck, D.E.2
Yang, C.S.3
-
36
-
-
0021154323
-
Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy
-
Mohandas, J., Marshall, J. J., Duggin, G. G., et al. Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy. Biochem. Pharmacol. 33: 1801, 1984.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 1801
-
-
Mohandas, J.1
Marshall, J.J.2
Duggin, G.G.3
-
37
-
-
0023893602
-
A histopathological study of analgesic hepatotoxicity in rabbit
-
Qamar, M. A., and Alam, S. M. A histopathological study of analgesic hepatotoxicity in rabbit. J. Pak. Med. Assoc. 38: 41, 1988.
-
(1988)
J. Pak. Med. Assoc.
, vol.38
, pp. 41
-
-
Qamar, M.A.1
Alam, S.M.2
-
38
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
-
Jollow, D. J., Mitchell, J. R., Potter, W. Z., et al. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J. Pharmacol. Exp. Ther. 187: 195, 1973.
-
(1973)
J. Pharmacol. Exp. Ther.
, vol.187
, pp. 195
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
-
39
-
-
0031713986
-
Disorders of the mitochondria
-
Treem, W. R., and Sokol, R. J.: Disorders of the mitochondria. Semin. Liver Dis. 18: 237, 1998.
-
(1998)
Semin. Liver Dis.
, vol.18
, pp. 237
-
-
Treem, W.R.1
Sokol, R.J.2
-
40
-
-
0028939262
-
An anesthetized model of lethal canine galactosamine fulminant hepatic failure
-
Sielaff, T. D., Hu, M. Y., Rollins, M. D., et al. An anesthetized model of lethal canine galactosamine fulminant hepatic failure. Hepatology 21: 796, 1995.
-
(1995)
Hepatology
, vol.21
, pp. 796
-
-
Sielaff, T.D.1
Hu, M.Y.2
Rollins, M.D.3
|