-
1
-
-
84985735713
-
Excluded volume as a determinant of macromolecular structure and reactivity
-
Minton, A. P. (1981) Excluded volume as a determinant of macromolecular structure and reactivity Biopolymers 20, 2093-2120
-
(1981)
Biopolymers
, vol.20
, pp. 2093-2120
-
-
Minton, A.P.1
-
2
-
-
0019883893
-
Effect of macromolecular crowding upon the structure and function of an enzyme: Glyceraldehyde-3-phosphate dehydrogenase
-
Minton, A. P. and Wilf, J. (1981) Effect of macromolecular crowding upon the structure and function of an enzyme: Glyceraldehyde-3-phosphate dehydrogenase Biochemistry 20, 4821-4826
-
(1981)
Biochemistry
, vol.20
, pp. 4821-4826
-
-
Minton, A.P.1
Wilf, J.2
-
3
-
-
41049090929
-
Macromolecular crowding and confinement: Biochemical, biophysical, and potential physiological consequences
-
Zhou, H. X., Rivas, G., and Minton, A. P. (2008) Macromolecular crowding and confinement: Biochemical, biophysical, and potential physiological consequences Annu. Rev. Biophys. 37, 375-397
-
(2008)
Annu. Rev. Biophys.
, vol.37
, pp. 375-397
-
-
Zhou, H.X.1
Rivas, G.2
Minton, A.P.3
-
4
-
-
0037470574
-
Effect of dextran on protein stability and conformation attributed to macromolecular crowding
-
Sasahara, K., McPhie, P., and Minton, A. P. (2003) Effect of dextran on protein stability and conformation attributed to macromolecular crowding J. Mol. Biol. 326, 1227-1237
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 1227-1237
-
-
Sasahara, K.1
McPhie, P.2
Minton, A.P.3
-
5
-
-
77956022419
-
Enthalpically driven peptide stabilization by protective osmolytes
-
Politi, R. and Harries, D. (2010) Enthalpically driven peptide stabilization by protective osmolytes Chem. Commun. 46, 6449-6451
-
(2010)
Chem. Commun.
, vol.46
, pp. 6449-6451
-
-
Politi, R.1
Harries, D.2
-
6
-
-
84867377395
-
Macromolecular crowding and protein stability
-
Wang, Y., Sarkar, M., Smith, A. E., Krois, A. S., and Pielak, G. J. (2012) Macromolecular crowding and protein stability J. Am. Chem. Soc. 134, 16614-16618
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 16614-16618
-
-
Wang, Y.1
Sarkar, M.2
Smith, A.E.3
Krois, A.S.4
Pielak, G.J.5
-
7
-
-
84870931817
-
Diversity in the mechanisms of cosolute action on biomolecular processes
-
in press.
-
Sukenik, S., Sapir, L., Politi, R., and Harries, D. Diversity in the mechanisms of cosolute action on biomolecular processes. Faraday Discuss. 2013, in press.
-
(2013)
Faraday Discuss.
-
-
Sukenik, S.1
Sapir, L.2
Politi, R.3
Harries, D.4
-
8
-
-
33344476423
-
Nanopore-protein interactions dramatically alter stability and yield of the native state in restricted spaces
-
Cheung, M. S. and Thirumalai, D. (2006) Nanopore-protein interactions dramatically alter stability and yield of the native state in restricted spaces J. Mol. Biol. 357, 632-643
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 632-643
-
-
Cheung, M.S.1
Thirumalai, D.2
-
9
-
-
77950792003
-
Diffusion, crowding & protein stability in a dynamic molecular model of the macterial cytoplasm
-
McGuffee, S. R. and Elcock, A. H. (2010) Diffusion, crowding & protein stability in a dynamic molecular model of the macterial cytoplasm PLoS Comput. Biol. 6, e1000694
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. 1000694
-
-
McGuffee, S.R.1
Elcock, A.H.2
-
10
-
-
84855848788
-
Variable interactions between protein crowders and biomolecular solutes are important in understanding cellular crowding
-
Feig, M. and Sugita, Y. (2012) Variable interactions between protein crowders and biomolecular solutes are important in understanding cellular crowding J. Phys. Chem. 116, 599-605
-
(2012)
J. Phys. Chem.
, vol.116
, pp. 599-605
-
-
Feig, M.1
Sugita, Y.2
-
11
-
-
0020855355
-
Hydrogen exchange and structural dynamics of proteins and nucleic acids
-
Englander, S. W. and Kallenbach, N. R. (1983) Hydrogen exchange and structural dynamics of proteins and nucleic acids Q. Rev. Biophys. 16, 521-655
-
(1983)
Q. Rev. Biophys.
, vol.16
, pp. 521-655
-
-
Englander, S.W.1
Kallenbach, N.R.2
-
12
-
-
77955676884
-
1H exchange to assess macromolecular crowding effects on globular-protein stability
-
1H exchange to assess macromolecular crowding effects on globular-protein stability Methods Enzymol. 466, 1-18
-
(2009)
Methods Enzymol.
, vol.466
, pp. 1-18
-
-
Miklos, A.C.1
Li, C.2
Pielak, G.J.3
-
13
-
-
0028787409
-
Effects of a naturally occurring compatible osmolyte on the internal dynamics of ribonuclease A
-
Wang, A., Robertson, A. D., and Bolen, D. W. (1995) Effects of a naturally occurring compatible osmolyte on the internal dynamics of ribonuclease A Biochemistry 34, 15096-15104
-
(1995)
Biochemistry
, vol.34
, pp. 15096-15104
-
-
Wang, A.1
Robertson, A.D.2
Bolen, D.W.3
-
14
-
-
0023652256
-
Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds
-
McPhalen, C. A. and James, M. N. G. (1987) Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds Biochemistry 26, 261-269
-
(1987)
Biochemistry
, vol.26
, pp. 261-269
-
-
McPhalen, C.A.1
James, M.N.G.2
-
15
-
-
0031552590
-
Amide proton exchange in CI2 probed by denaturants and temperature
-
Itzhaki, L. S., Neiva, J., and Fersht, A. (1997) Amide proton exchange in CI2 probed by denaturants and temperature J. Mol. Biol. 270, 89-98
-
(1997)
J. Mol. Biol.
, vol.270
, pp. 89-98
-
-
Itzhaki, L.S.1
Neiva, J.2
Fersht, A.3
-
16
-
-
77953145949
-
Effect of Ficoll 70 on thermal stability and structure of creatine kinase
-
Wang, Y., He, H., and Li, S. (2010) Effect of Ficoll 70 on thermal stability and structure of creatine kinase Biochemistry (Moscow, Russ. Fed.) 75, 648-654
-
(2010)
Biochemistry (Moscow, Russ. Fed.)
, vol.75
, pp. 648-654
-
-
Wang, Y.1
He, H.2
Li, S.3
-
17
-
-
70349310244
-
Nonadditive effects of mixed crowding on protein stability
-
Batra, J., Xu, K., and Zhou, H.-X. (2009) Nonadditive effects of mixed crowding on protein stability Proteins: Struct., Funct., Bioinf. 77, 133-138
-
(2009)
Proteins: Struct., Funct., Bioinf.
, vol.77
, pp. 133-138
-
-
Batra, J.1
Xu, K.2
Zhou, H.-X.3
-
18
-
-
37649016316
-
Molecular crowding enhances native structure and stability of α/β protein flavodoxin
-
Stagg, L., Zhang, S.-Q., Cheung, M. S., and Wittung-Stafshede, P. (2007) Molecular crowding enhances native structure and stability of α/β protein flavodoxin Proc. Natl. Acad. Sci. U.S.A. 104, 18976-18981
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 18976-18981
-
-
Stagg, L.1
Zhang, S.-Q.2
Cheung, M.S.3
Wittung-Stafshede, P.4
-
19
-
-
77955249021
-
Factors defining effects of macromolecular crowding on protein stability: An in vitro/in silico case study using cytochrome c
-
Christiansen, A., Wang, Q., Samiotakis, A., Cheung, M. S., and Wittung-Stafshede, P. (2010) Factors defining effects of macromolecular crowding on protein stability: An in vitro/in silico case study using cytochrome c Biochemistry 49, 6519-6530
-
(2010)
Biochemistry
, vol.49
, pp. 6519-6530
-
-
Christiansen, A.1
Wang, Q.2
Samiotakis, A.3
Cheung, M.S.4
Wittung-Stafshede, P.5
-
20
-
-
79960962805
-
The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics
-
Wang, Q., Liang, K.-C., Czader, A., Waxham, M. N., and Cheung, M. S. (2011) The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics PLoS Comput. Biol. 7, e1002114
-
(2011)
PLoS Comput. Biol.
, vol.7
, pp. 1002114
-
-
Wang, Q.1
Liang, K.-C.2
Czader, A.3
Waxham, M.N.4
Cheung, M.S.5
-
21
-
-
79952526173
-
Power-law dependence of the melting temperature of ubiquitin on the volume fraction of macromolecular crowders
-
Waegele, M. M. and Gai, F. (2011) Power-law dependence of the melting temperature of ubiquitin on the volume fraction of macromolecular crowders J. Chem. Phys. 134, 095104
-
(2011)
J. Chem. Phys.
, vol.134
, pp. 095104
-
-
Waegele, M.M.1
Gai, F.2
-
22
-
-
78049291945
-
Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding
-
Dhar, A., Samiotakis, A., Ebbinghaus, S., Nienhaus, L., Homouz, D., Gruebele, M., and Cheung, M. S. (2010) Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding Proc. Natl. Acad. Sci. U.S.A. 107, 17586-17591
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 17586-17591
-
-
Dhar, A.1
Samiotakis, A.2
Ebbinghaus, S.3
Nienhaus, L.4
Homouz, D.5
Gruebele, M.6
Cheung, M.S.7
-
23
-
-
34249787868
-
Destabilised mutants of ubiquitin gain equal stability in crowded solutions
-
Roberts, A. and Jackson, S. E. (2007) Destabilised mutants of ubiquitin gain equal stability in crowded solutions Biophys. Chem. 128, 140-149
-
(2007)
Biophys. Chem.
, vol.128
, pp. 140-149
-
-
Roberts, A.1
Jackson, S.E.2
-
24
-
-
44649175880
-
Effect of macromolecular crowding on the stability of monomeric glutaredoxin 2 and dimeric glutathione transferase A1-1
-
Kuhnert, D. C., Gildenhuys, S., and Dirr, H. W. (2008) Effect of macromolecular crowding on the stability of monomeric glutaredoxin 2 and dimeric glutathione transferase A1-1 S. Afr. J. Sci. 104, 76-80
-
(2008)
S. Afr. J. Sci.
, vol.104
, pp. 76-80
-
-
Kuhnert, D.C.1
Gildenhuys, S.2
Dirr, H.W.3
-
25
-
-
44349088135
-
Residue-level interrogation of macromolecular crowding effects on protein stability
-
Charlton, L. M., Barnes, C. O., Li, C., Orans, J., Young, G. B., and Pielak, G. J. (2008) Residue-level interrogation of macromolecular crowding effects on protein stability J. Am. Chem. Soc. 130, 6826-6830
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 6826-6830
-
-
Charlton, L.M.1
Barnes, C.O.2
Li, C.3
Orans, J.4
Young, G.B.5
Pielak, G.J.6
-
26
-
-
77955707910
-
Volume exclusion and soft interaction effects on protein stability under crowded conditions
-
Miklos, A. C., Li, C., Sharaf, N. G., and Pielak, G. J. (2010) Volume exclusion and soft interaction effects on protein stability under crowded conditions Biochemistry 49, 6984-6991
-
(2010)
Biochemistry
, vol.49
, pp. 6984-6991
-
-
Miklos, A.C.1
Li, C.2
Sharaf, N.G.3
Pielak, G.J.4
-
27
-
-
1842473533
-
Osmolyte-induced changes in protein conformational equilibria
-
Saunders, A. J., Davis-Searles, P. R., Allen, D. L., Pielak, G. J., and Erie, D. A. (2000) Osmolyte-induced changes in protein conformational equilibria Biopolymers 53, 293-307
-
(2000)
Biopolymers
, vol.53
, pp. 293-307
-
-
Saunders, A.J.1
Davis-Searles, P.R.2
Allen, D.L.3
Pielak, G.J.4
Erie, D.A.5
-
28
-
-
0034987618
-
Interpreting the effects of small uncharged solutes on protein-folding equilibria
-
Davis-Searles, P. R., Saunders, A. J., Erie, D. A., Winzor, D. J., and Pielak, G. J. (2001) Interpreting the effects of small uncharged solutes on protein-folding equilibria Annu. Rev. Biophys. Biomol. Struct. 30, 271-306
-
(2001)
Annu. Rev. Biophys. Biomol. Struct.
, vol.30
, pp. 271-306
-
-
Davis-Searles, P.R.1
Saunders, A.J.2
Erie, D.A.3
Winzor, D.J.4
Pielak, G.J.5
-
29
-
-
0032374095
-
Sugar-induced molten-globule model
-
Davis-Searles, P. R., Morar, A. S., Saunders, A. J., Erie, D. A., and Pielak, G. J. (1998) Sugar-induced molten-globule model Biochemistry 37, 17048-17053
-
(1998)
Biochemistry
, vol.37
, pp. 17048-17053
-
-
Davis-Searles, P.R.1
Morar, A.S.2
Saunders, A.J.3
Erie, D.A.4
Pielak, G.J.5
-
30
-
-
0020123955
-
Calorimetric study on thermal denaturation of lysozyme in polyol-water mixtures
-
Gekko, K. (1982) Calorimetric study on thermal denaturation of lysozyme in polyol-water mixtures J. Biochem. 91, 1197-1204
-
(1982)
J. Biochem.
, vol.91
, pp. 1197-1204
-
-
Gekko, K.1
-
31
-
-
76249129238
-
Influence of osmolytes and denaturants on the structure and enzyme activity of α-chymotrypsin
-
Attri, P., Venkatesu, P., and Lee, M.-J. (2010) Influence of osmolytes and denaturants on the structure and enzyme activity of α-chymotrypsin J. Phys. Chem. B 114, 1471-1478
-
(2010)
J. Phys. Chem. B
, vol.114
, pp. 1471-1478
-
-
Attri, P.1
Venkatesu, P.2
Lee, M.-J.3
-
32
-
-
0035937247
-
Structure and functionality of a designed p53 dimer
-
Davison, T. S., Nie, X., Ma, W., Lin, Y., Kay, C., Benchimol, S., and Arrowsmith, C. H. (2001) Structure and functionality of a designed p53 dimer J. Mol. Biol. 307, 605-617
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 605-617
-
-
Davison, T.S.1
Nie, X.2
Ma, W.3
Lin, Y.4
Kay, C.5
Benchimol, S.6
Arrowsmith, C.H.7
-
33
-
-
63149177937
-
Using NMR to distinguish viscosity effects from nonspecific protein binding under crowded conditions
-
Li, C. and Pielak, G. J. (2009) Using NMR to distinguish viscosity effects from nonspecific protein binding under crowded conditions J. Am. Chem. Soc. 131, 1368-1369
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 1368-1369
-
-
Li, C.1
Pielak, G.J.2
-
34
-
-
77955686807
-
Effects of proteins on protein diffusion
-
Wang, Y., Li, C., and Pielak, G. J. (2010) Effects of proteins on protein diffusion J. Am. Chem. Soc. 132, 9392-9397
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 9392-9397
-
-
Wang, Y.1
Li, C.2
Pielak, G.J.3
-
35
-
-
0034745484
-
Second virial coefficients as a measure of protein-osmolyte interactions
-
Weatherly, G. T. and Pielak, G. J. (2001) Second virial coefficients as a measure of protein-osmolyte interactions Protein Sci. 10, 12-16
-
(2001)
Protein Sci.
, vol.10
, pp. 12-16
-
-
Weatherly, G.T.1
Pielak, G.J.2
-
36
-
-
77955044557
-
Macromolecular crowding remodels the energy landscape of a protein by favoring a more compact unfolded state
-
Hong, J. and Gierasch, L. M. (2010) Macromolecular crowding remodels the energy landscape of a protein by favoring a more compact unfolded state J. Am. Chem. Soc. 132, 10445-10452
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 10445-10452
-
-
Hong, J.1
Gierasch, L.M.2
-
37
-
-
0027310845
-
The control of protein stability and association by weak interactions with water: How do solvents affect these processes?
-
Timasheff, S. N. (1993) The control of protein stability and association by weak interactions with water: How do solvents affect these processes? Annu. Rev. Biophys. Biomol. Struct. 22, 67-97
-
(1993)
Annu. Rev. Biophys. Biomol. Struct.
, vol.22
, pp. 67-97
-
-
Timasheff, S.N.1
-
38
-
-
33749365298
-
A molecular mechanism for osmolyte-induced protein stability
-
Street, T. O., Bolen, D. W., and Rose, G. D. (2006) A molecular mechanism for osmolyte-induced protein stability Proc. Natl. Acad. Sci. U.S.A. 103, 13997-14002
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 13997-14002
-
-
Street, T.O.1
Bolen, D.W.2
Rose, G.D.3
-
39
-
-
80052319202
-
Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains
-
Auton, M., Rösgen, J., Sinev, M., Holthauzen, L. M. F., and Bolen, D. W. (2011) Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains Biophys. Chem. 159, 90-99
-
(2011)
Biophys. Chem.
, vol.159
, pp. 90-99
-
-
Auton, M.1
Rösgen, J.2
Sinev, M.3
Holthauzen, L.M.F.4
Bolen, D.W.5
-
40
-
-
0023443673
-
On the separation ability of various Ficoll gradient solutions in zonal centrifugation
-
Lavrenko, P. N., Mikriukova, O. I., and Okatova, O. V. (1987) On the separation ability of various Ficoll gradient solutions in zonal centrifugation Anal. Biochem. 166, 287-297
-
(1987)
Anal. Biochem.
, vol.166
, pp. 287-297
-
-
Lavrenko, P.N.1
Mikriukova, O.I.2
Okatova, O.V.3
-
41
-
-
0019888281
-
The stabilization of proteins by sucrose
-
Lee, J. C. and Timasheff, S. N. (1981) The stabilization of proteins by sucrose J. Biol. Chem. 256, 7193-7201
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 7193-7201
-
-
Lee, J.C.1
Timasheff, S.N.2
-
42
-
-
0014722597
-
Enthalpy-entropy compensation phenomena in water solutions of proteins and small molecules: A ubiquitous property of water
-
Lumry, R. and Rajender, S. (1970) Enthalpy-entropy compensation phenomena in water solutions of proteins and small molecules: A ubiquitous property of water Biopolymers 9, 1557-1559
-
(1970)
Biopolymers
, vol.9
, pp. 1557-1559
-
-
Lumry, R.1
Rajender, S.2
|