Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay

Toxicology in Vitro

Volumn 27, Issue 2, 2013, Pages 651-661

  Lalko, J F ^a   Dearman, R J ^a   Gerberick, G F ^b   Troutman, J A ^b   Api, A M ^c   Kimber, I ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

Author keywords

Chemical allergens; Hazard identification; Peptide reactivity; Respiratory sensitization; Skin sensitization

Indexed keywords

ALLERGEN; CHLORHEXIDINE; CYSTEINE; ETHYLENEDIAMINE; HAPTEN; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LYSINE; PEPTIDE; PEROXIDASE; PIPERAZINE;

ALLOIMMUNITY; ARTICLE; CHROMATOGRAPHY; CLINICAL FEATURE; HUMAN; MASS SPECTROMETRY; SENSITIZATION;

ALLERGENS; BIOLOGICAL ASSAY; CYSTEINE; HAPTENS; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LYSINE; PEPTIDES; RESPIRATORY HYPERSENSITIVITY;

ARMORACIA RUSTICANA;

EID: 84870876983     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.10.016     Document Type: Article

References (39)

1. Abuknesha R.A., Jeganathan F., Wu J., Baalawy Z. Labeling of biotin antibodies with horseradish peroxidase using cyanuric chloride. Nat. Protoc. 2009, 4:452-460.
2. Aleksic M., Thain E., Roger D., Saib O., Davies M., Li J., Aptula A., Zazzeroni R. Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment. Toxicol. Sci. 2009, 108:40-411.
3. Aptula A.O., Patlewicz G., Roberts D.W., Schultz T.W. Non-enzymatic glutathione reactivity and in vitro toxicity: a non-animal approach to skin sensitisation. Toxicol. In Vitro 2006, 20:239-247.
4. Azevedo A.M., Martins V.C., Prazeres D.F.M., Vojinovic V., Cabral J.M.S., Fonseca L.P. Horseradish peroxidase: a valuable tool in biotechnology. Biotechnol. Annu. Rev. 2003, 9:199-247.
5. Barbosa J., Hernandez-Cassou S., Sanz-Nebot V., Toto I. Variation of acidity constants of peptides in acetonitrile-water mixtures with solvent composition: effect of preferential solvation. J. Peptide Res. 1997, 50:14-24.
6. Basketter D.A., Kimber I. Assessing the potency of respiratory allergens: uncertainties and challenges. Regul. Toxicol. Pharmacol. 2011, 61:365-372.
7. Bernstein D.I., Cartier A., Cote J., Malo J.L., Boulet L.P., Wanner M., L'Archeveque J., Trudeau C., Lummus Z. Diisocyanate antigen stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma. Am. J. Respir. Crit. Care Med. 2002, 166:445-450.
8. Bernstein I.L., Chan-Yeung M., Malo J.-L., Bernstein D.I. Asthma in the Workplace 2006, Taylor and Francis, New York, NY. third ed.
9. Cartier A., Grammer L., Malo J.-L., Lagier F., Ghezzo H., Harris K., Patterson R. Specific serum antibodies against isocyanates: association with occupational asthma. J. Allergy Clin. Immunol. 1989, 84:507-514.
10. Chipinda I., Ajibola R.O., Morakinyo M.K., Ruwona T.B., Simoyi R.H., Siegel P.D. Rapid and simple kinetic screening assay for electrophilic dermal sensitizers using nitrobenzenethiol. Chem. Res. Toxicol. 2010, 23:918-925.
11. Enoch S.J., Roberts D.W., Cronin M.T.D. Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. Chem. Res. Toxicol. 2009, 22:1447-1453.
12. Enoch S.J., Roberts D.W., Cronin M.T.D. Mechanistic category formation for the prediction of respiratory sensitization. Chem. Res. Toxicol. 2010, 23:1547-1555.
13. Gerberick G.F., Vassallo J.D., Bailey R.E., Chaney J.G., Morrall S.W., Lepoittevin J.P. Development of a peptide reactivity assay for screening contact allergens. Toxicol. Sci. 2004, 81:332-343.
14. Gerberick G.F., Ryan C.A., Kern P.S., Schlatter H., Dearman R.J., Kimber I., Patlewicz G.Y., Basketter D.A. Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 2005, 16:157-202.
15. Gerberick G.F., Vassallo J.D., Foertsch L.M., Price B.B., Chaney J.G., Lepoittevin J.P. Quantification of a chemical peptide reactivity for screening contact allergens: a classification tree model approach. Toxicol. Sci. 2007, 97:417-427.
16. Gerberick G.F., Troutman J.A., Foertsch L.M., Vassallo J.D., Quijano M., Dobson R.L.M., Goebel C., Lepoittevin J.-P. Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system. Toxicol. Sci. 2009, 112:164-174.
17. HSE (Health and Safety Executive), 2001. Asthmagen? Critical assessments of the evidence for agents implicated in occupational asthma. Available from: http://www.hse.gov.uk/asthma/asthmagen.pdf.
18. Isola D., Kimber I., Sarlo K., Lalko J., Sipes I.G. Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty?. J. Appl. Toxicol. 2008, 28:249-253.
19. Kato H., Okamoto M., Yamashita K., Nakamura Y., Fukumori Y., Nakai K., Kaneko H. Peptide-binding assessment using mass spectrometry as a new screening method for skin sensitization. J. Toxicol. Sci. 2003, 28:19-24.
20. Kern P.S., Gerberick G.F., Ryan C.A., Kimber I., Aptula A., Basketter D.A. Local lymph node data for the evaluation of skin sensitization alternatives: a second compilation. Dermatitis 2010, 21:8-32.
21. Kimber I., Agius R., Basketter D.A., Corsini A., Cullinan P., Dearman R.J., Gimenez-Arnau E., Greenwell L., Hartung T., Kuper F., Maestrelli P., Roggen E., Rovida C. Chemical respiratory allergy: opportunities for hazard identification and characterization. The report and recommendations of ECVAM workshop 60. ATLA 2007, 35:243-265.
22. Kimber I., Basketter D.A., Dearman R.J. Chemical allergens: what are the issues?. Toxicology 2010, 268:139-142.
23. Kimber I., Basketter D.A., Gerberick G.F., Ryan C.A., Dearman R.J. Chemical allergy: translating biology into hazard characterization. Toxicol. Sci. 2011, 120:S238-S268.
24. Lalko J.F., Kimber I., Dearman R.J., Gerberick G.F., Sarlo K., Api A.M. Chemical reactivity measurements: potential for characterization of respiratory chemical allergens. Toxicol. In Vitro 2011, 25:433-445.
25. Lalko J.F., Kimber I., Gerberick G.F., Foertsch L.M., Api A.M., Dearman R.J. The direct peptide reactivity assay: selectivity of chemical respiratory allergens. Toxicol. Sci. 2012, 129:421-431.
26. Layton G.T., Stanworth D.R., Amos H.E. The specificity of murine polyclonal and monocloncal antibodies to the haptenic drug chlorhexidine induced by chlorine-generated chlorhexidine-protein conjugates. Clin. Exp. Allergy 1987, 69:157-165.
27. Lepoittevin J.-P., Basketter D.A., Goossens A., Karlberg A.-T. Allergic Contact Dermatitis: The Molecular Basis 1998, Springer, Berlin.
28. Molin S.O., Nygren H., Dolonius L., Hansson H.A. A kinetic study of the reaction between glutaraldehyde and horseradish peroxidase. J. Histochem. Cytochem. 1978, 25:1053-1056.
29. Modesto R.R., Pesce A.J. Use of tolylene diisocyanate for the preparation of a peroxidase-labelled antibody conjugate - quantitation of the amount of diisocyanate bound. Biochim. Biophys. Acta Protein Struct. 1973, 295:283-295.
30. Natsch A., Gfeller H., Rothaupt M., Ellis G. Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. Toxicol. In Vitro 2007, 21:1220-1226.
31. Natsch A., Gfeller H. LC-MS-based characterization of the peptide reactivity of chemicals to improve the in vitro prediction of the skin sensitization potential. Toxicol. Sci. 2008, 106:464-478.
32. O'Brien A.M., Smith A.T., Fagain C. Effects of phthalic anhydride modification on horseradish peroxidase stability and activity. Biotechnol. Bioeng. 2003, 81:233-240.
33. Reichardt C. Solvents and Solvent Effects in Organic Chemistry 2010, Wiley-VCH, Weinheim.
34. Schultz T.W., Yarbrough J.W., Johnson E.L. Structure-activity relationships for reactivity of carbonyl-containing compounds with glutathione. SAR QSAR Environ. Res. 2005, 16:313-322.
35. Smith C., Hotchkiss S.A.M. Allergic Contact Dermatitis: Chemical and Metabolic Mechanisms 2001, Informa Healthcare, London.
36. Troutman J.A., Foertsch L.M., Kern P.S., Dai H.J., Quijano M., Dobson R.L.M., Lalko J.F., Lepoittevin J.-P., Gerberick G.F. The incorporation of lysine into the peroxidase peptide reactivity assay for skin sensitization assessments. Toxicol. Sci. 2011, 2:422-436.
37. Vandenplas O., Toren K., Blanc P.D. Health and socioeconomic impact of work-related asthma. Eur. Respir. J. 2003, 22:689-697.
38. Weltzien H.U., Moulon C., Martic S., Padovan E., Hartmann U., Kohler J. T cell immune responses to haptens. Structural models for allergic and autoimmune reactions. Toxicology 1996, 107:141-151.
39. Wisnewski A.V., Hettick J.M., Siegel P.D. Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin. Chem. Res. Toxicol. 2011, 24:1686-1693.