Severe anion gap metabolic acidosis from acetaminophen use secondary to 5-oxoproline (pyroglutamic acid) accumulation

American Journal of the Medical Sciences

Volumn 344, Issue 6, 2012, Pages 501-504

  Zand, Ladan ^a   Muriithi, Angela ^a   Nelsen, Eric ^a   Franco, Pablo M ^a   Greene, Eddie L ^a   Qian, Qi ^a   El Zoghby, Ziad M ^a  

^a MAYO CLINIC   (United States)

Author keywords

5 Oxoproline; Acetaminophen; Anion gap metabolic acidosis; Pyroglutamic acid

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BICARBONATE; HYPERTENSIVE FACTOR; PARACETAMOL; PYROGLUTAMIC ACID;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL ABUSE; AMINO ACID URINE LEVEL; ANION GAP; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE REPORT; CHOLECYSTITIS; CHRONIC LIVER DISEASE; CHRONIC PANCREATITIS; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG URINE LEVEL; DRUG WITHDRAWAL; EMERGENCY WARD; FEMALE; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL STROMAL TUMOR; HIGH ANION GAP METABOLIC ACIDOSIS; HUMAN; INGESTION; LETHARGY; LIVER TRANSPLANTATION; METABOLIC ACIDOSIS; SEPTIC SHOCK; WOUND DEHISCENCE;

EID: 84870875721     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e318259bd45     Document Type: Article

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