Fetal brain lesions in tuberous sclerosis complex: TORC1 activation and inflammation

Brain Pathology

Volumn 23, Issue 1, 2013, Pages 45-59

  Prabowo, Avanita S ^a   Anink, Jasper J ^a   Lammens, Martin ^b   Nellist, Mark ^c   Van Den Ouweland, Ans M W ^c   Adle Biassette, Homa ^d   Sarnat, Harvey B ^e   Flores Sarnat, Laura ^f   Crino, Peter B ^g   Aronica, Eleonora ^a,h  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d HÔPITAL ROBERT DEBRÉ   (France)

^e ALBERTA CHILDREN'S HOSPITAL   (Canada)

^f UNIVERSITY OF CALGARY   (Canada)

^g HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^h STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

Author keywords

development; giant cells; major histocompatibility complex (MHC) class I; microglia; phosphorylated ribosomal protein S6; TORC1 signaling; tubers

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; INITIATION FACTOR 4E BINDING PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYC PROTEIN; PROTEIN P70; PROTEIN S6; TARGET OF RAPAMYCIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUBERIN; TUBEROUS SCLEROSIS COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; BRAIN DAMAGE; BRAIN DEVELOPMENT; BRAIN MALFORMATION; FEMALE; FETUS; FETUS DISEASE; GESTATION PERIOD; GIANT CELL; HUMAN; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBEPENDYMAL GIANT CELL ASTROCYTOMA; T LYMPHOCYTE;

ANTIGENS, CD; BRAIN; DNA MUTATIONAL ANALYSIS; ENCEPHALITIS; FEMALE; FETUS; GENE EXPRESSION REGULATION, NEOPLASTIC; GESTATIONAL AGE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MULTIPROTEIN COMPLEXES; MUTATION; NERVE TISSUE PROTEINS; PREGNANCY; PRENATAL DIAGNOSIS; RECEPTORS, IMMUNOLOGIC; TOLL-LIKE RECEPTORS; TOR SERINE-THREONINE KINASES; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 84870873020     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2012.00616.x     Document Type: Article

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