Research progress of autophagy and pulmonary diseases

Progress in Biochemistry and Biophysics

Volumn 39, Issue 9, 2012, Pages 861-868

  Yang, Li ^a   Xiao, Ling ^a   Chen, Lin Xi ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Autophagy; COPD; Lung cancer; Pulmonary emphysema; Pulmonary hypertension; Pulmonary tuberculosis

Indexed keywords

EUKARYOTA;

EID: 84870838894     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2011.00429     Document Type: Review

References (39)

1. Bursch W. The autophagosomal lysosomal compartment in programmed cell death. Cell Death Differ, 2001,8(6): 569-581 (Pubitemid 32590778)
2. Sapunar D, Vilovic K, England M, el al. Morphological diversity of dying cells during regression of the human tail. Ann Anat, 2001, 183(3): 217-222 (Pubitemid 32447737)
3. Mizushima N, Levine B, Cuervo A M, et al. Autophagy fights disease through cellular self-digestion. Nature, 2008, 451(7182): 1069-1075 (Pubitemid 351317450)
4. Pak O, Aldashev A, Welsh D, et al. The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J, 2007, 30(2): 364-372 (Pubitemid 47201724)
5. Ng C S, Wan S, Yim A P. Pulmonary ischaemia-reperfusion injury: Role of apoptosis. Eur Respir, 2005, 25(2): 356-363 (Pubitemid 40246539)
6. Pauwels R A, Buist A S, Ma P, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National heart, lung, and blood institute and world health organization global initiative for chronic obstructive lung disease (GOLD). Respir Care, 2001,46(8): 798-825 (Pubitemid 33759920)
7. Kim H P, Wang X, Chen Z H, et al. Autophagic proteins regulate cigarette smoke-induced apoptosis: Protective role of heme oxygenase-1. Autophagy, 2008,4(7): 887-895
8. Chen Z H, Kim H P, Sciurba F C, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One, 2008,3(10): e3316
9. Weinberger B, Laskin J D, Sunil V R, et al. Sulfur mustard-induced pulmonary injury: Therapeutic approaches to mitigating toxicity. Pulm Pharmacol Ther, 2011,24(1): 92-99
10. Malaviya R, Sunil V R, Cervelli J, et al. Inflammatory effects of inhaled sulfur mustard in rat lung. Toxicol Appl Pharmacol, 2010, 248(2): 89-99
11. Chen G L, Liu H L, Sun Y, et al. PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol, 2009, 1(1): 37-45
12. Lee S J, Ryter S W, Xu J F, et al. Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. Am J Respir Cell Mol Biol, 2011,45(4): 867-873
13. Li J J, Hartono D, Ong C N, et al. Autophagy and oxidative stress associated with gold nanoparticles. Biomaterials, 2010, 31 (23): 5996-6003
14. Chandel N S, McClintock D S, Feliciano C E, et al. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1 alpha during hypoxia: A mechanism of O2 sensing. J Biol Chem, 2000,275(33): 25130-25138
15. Zhang H, Bosch-Marce M, Shimoda L A, et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem, 2008, 283(16): 10892-10903
16. Inoue D, Kubo H, Taguchi K, et al. Inducible disruption of autophagy in the lung causes airway hyper-responsiveness. Biochem Biophys Res Commun, 2011,405(1): 13-18
17. Chen Z H, Lam H C, Jin Y, et al. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci USA, 2010,107(44): 18880-18885
18. Kondo Y, Kanzawa T, Sawaya R, et al. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer, 2005,5(9): 726-734 (Pubitemid 41486365)
19. Liang X H, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature, 1999, 402(6762): 672-676 (Pubitemid 129516338)
20. Yue Z, Jin S, Yang C, et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA, 2003,100(25): 15077-15082 (Pubitemid 37518019)
21. Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest, 2003,112(12): 1809-1820 (Pubitemid 38063704)
22. Gills J J, Lopiccolo J, Tsurutani J, et al. Nelfinavir, a lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res, 2007,13(17): 5183-5194 (Pubitemid 47502088)
23. Zois C E, Giatromanolaki A, Kainulainen H, et al. Lung autophagic response following exposure of mice to whole body irradiation, with and without amifostine. Biochem Biophys Res Commun, 2011,404(1): 552-558
24. Karpathiou G, Sivridis E, Koukourakis M I, et al. Light-chain 3A autophagic acivity and prognostic significance in non-small cell lung carcinomas. Chest, 2010,140(1): 127-134
25. Yue Z, Jin S, Yang C, et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA, 2003,100(25): 15077-15082 (Pubitemid 37518019)
26. Han W, Pan H, Chen Y, et al. EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One, 2011,6(6): e18691
27. Ohtani S, Iwamaru A, Deng W, et al. Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy. Cancer Res, 2007,67(13): 6293-6303 (Pubitemid 47037512)
28. William N H, Jin S K, Yang J M. A matter of life or death(or both): understanding autophagy in caner. Clin Cancer Res, 2006, 12(7): 1961-1965
29. Zheng L W, Li Y, Ge D, et al. Synthesis of novel oxime-containing pyrazole derivatives and discovery of regulators for apoptosis and autophagy in A549 lung cancer cells. Bioorg Med Chem Lett, 2010, 20(16): 4766-4770
30. Li J, Wang X L, Fang Y C, et al. Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells. J Asian Nat Prod Res, 2010,12(11): 992-1000
31. Choi C H, Jung Y K, Oh S H. Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines. Free Radie Biol Med, 2010,49(2): 245-257
32. Fu X, Pan Y, Wang J, et al. The role of autophagy in human lung cancer cell line A549 induced by Vinorelbine. Chin J Lung Cancer, 2008,11(3): 345-348 (Pubitemid 351976665)
33. Moreira-Leite F F, Harrison L R, Mironov A, et al. Inducible EGFR T790M-mediated gefitinib resistance in non-small cell lung cancer cells does not modulate sensitivity to P1103 provoked autophagy. J Thorac Oncol, 2010, 5(6): 765-777
34. Schmid K, Bago-Horvath Z, Berger W, et al. Dual inhibition of EGFR and mTOR pathways in small cell lung cancer. Br J Cancer, 2010,103(5): 622-628
35. Kim K. W, Moretti L, Mitchell L R, et al. Combined Bcl-2/ mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model. Clin Cancer Res, 2009, 15(19): 6096-6105
36. Kim K W, Hwang M, Moretti L, et al. Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy, 2008,4(5): 659-668
37. Peng P L, Kuo W H, Tseng H C, et al. Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death. Int J Radiat Oncol Biol Phys, 2008,70(2): 529-542
38. Intemann C D, Thye T, Niemann S, et al. Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog, 2009,5(9): e1000577
39. Lee S J, Smith A, Guo L, et al. Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med, 2011,183(5): 649-658